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Scholar Results 1 - 10 of about 101 related to Tang: Evidence for a role of superoxide generation in glucose-induced β-cell dysfunction in vivo. (0.14 sec) 

Evidence for a role of superoxide generation in glucose-induced β-cell dysfunction in vivo

- shouxi.net
C Tang, P Han, AI Oprescu, SC Lee, AV … - Diabetes, 2007 - Am Diabetes Assoc
RESULTS— A 48-h glucose infusion decreased glucose-stimulated insulin
secretion (GSIS) and elevated reactive oxygen species (ROS), total superoxide,
and mitochondrial superoxide in freshly isolated islets. TPO prevented the ...
Cited by 24 - Related articles - BL Direct - All 4 versions

Defective glucose-stimulated insulin release in the diabetic Goto-Kakizaki (GK) rat coincides …

- endojournals.org
H Mosen, A Salehi, P Alm, R Henningsson, J … - Endocrinology, 2005 - Endocrine Soc
The Goto-Kakizaki (GK) rat displays a markedly reduced insulin response to
glucose, a defect that is thought to be coupled to an impaired glucose signaling
in the ß-cell. We have examined whether carbon monoxide (CO), derived from ...
Cited by 10 - Related articles - All 4 versions

Nitric oxide inhibits, and carbon monoxide activates, islet acid {alpha}-glucoside hydrolase …

- endocrinology-journals.org
H Mosen, A Salehi, R Henningsson, I … - Journal of Endocrinology, 2006 - Soc Endocrinology
We have studied the influence of nitric oxide (NO) and carbon monoxide (CO),
putative messenger molecules in the brain as well as in the islets of
Langerhans, on glucose-stimulated insulin secretion and on the activities ...
Cited by 10 - Related articles - BL Direct - All 3 versions

Carbon monoxide blocks oxidative stress-induced hepatocyte apoptosis via inhibition of the …

- rug.nl [PDF] 
L Conde de la Rosa, TE Vrenken, RA … - Free Radical Biology and Medicine, 2008 - Elsevier
Most chronic liver diseases are accompanied by oxidative stress, which may
induce apoptosis in hepatocytes and liver injury. Oxidative stress induces heme
oxygenase-1 (HO-1) expression. This stress-responsive cytoprotective ...
Cited by 3 - Related articles - All 4 versions

Haeme-oxygenase 1 expression in rat pancreatic beta cells is stimulated by …


JC Jonas, Y Guiot, J Rahier, JC Henquin - Diabetologia, 2003 - Springer
Aim/hypothesis. Increased expression of haeme-oxyge- nase 1 (HO1) and other
antioxidant enzymes could im- prove pancreatic beta-cell survival under
stressful condi- tions, including hyperglycaemia. However, how hyper- ...
Cited by 20 - Related articles - BL Direct - All 5 versions

Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in …


JF Ndisang, N Lane, A Jadhav - Journal of Hypertension, 2008 - journals.lww.com
Background: Aldosterone is a mineral corticoid hormone that is produced in
response to angiotensin-II, and like angiotensin-II, stimulates inflammation,
oxidative stress, and fibrosis by activating nuclear factor-κB and ...
Cited by 13 - Related articles - BL Direct - All 3 versions

Cardiac expression of adiponectin and its receptors in streptozotocin-induced diabetic rats


Z Guo, Z Xia, VG Yuen, JH McNeill - Metabolism, 2007 - Elsevier
Adiponectin can improve both glucose metabolism and insulin resistance via the
adenosine monophosphate–activated protein kinase (AMPK) signaling pathway.
Activated AMPK phosphorylates a variety of intracellular proteins, ...
Cited by 12 - Related articles - All 16 versions

Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase …

- endocrinology-journals.org
Y Liu, Y Nakagawa, Y Wang, L Liu, H Du, W … - Journal of Molecular Endocrinology, 2008 - Soc Endocrinology
Intracellular glucocorticoid (GC) receptor (GR) function determines tissue
sensitivity to GCs and strongly affects the development of type 2 diabetes and
obesity. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) mediates ...
Cited by 5 - Related articles - All 3 versions

Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-{kappa} B …

- physiology.org
Y Wei, JR Sowers, SE Clark, W Li, CM … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc
Reduced insulin sensitivity is a key factor in the pathogenesis of type 2
diabetes and hypertension. Skeletal muscle insulin resistance is particularly
important for its major role in insulin-mediated glucose disposal. ...
Cited by 18 - Related articles - BL Direct - All 3 versions

Adiponectin and its potential in the treatment of obesity, diabetes and insulin resistance.


M Haluzik - Current opinion in investigational drugs (London, …, 2005 - ncbi.nlm.nih.gov
Adiponectin is a protein hormone produced exclusively by adipocytes. Its
circulating levels are decreased in individuals with obesity, atherosclerosis
and insulin resistance, suggesting that its deficiency may have a causal ...
Cited by 17 - Related articles - BL Direct - All 3 versions


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