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Scholar Results 1 - 10 of about 101 related to Falchi: Quantitative Linkage Analysis for Pancreatic B-cell Function and Insulin Resistance.... (0.13 sec) 

Quantitative Linkage Analysis for Pancreatic B-cell Function and Insulin Resistance …


M Falchi, SG Wilson, D Paximadas, R Swaminathan, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Genome-wide variance component linkage analysis using 2,231 genetic markers
identified a highly significant quantitative trait locus for BCF on chromosome 10p15 (logarithm
of odds [LOD] 6.2, P = 0.0001), a region recently shown to contain a functional variant for ...
Cited by 1 - Related articles - BL Direct - All 7 versions

Quantitative Trait Loci on Chromosome 8q24 for Pancreatic β-Cell Function and …


P An, BI Freedman, SS Rich, SA Mandel, DK Arnett, RH … - Diabetes, 2006 - Am Diabetes Assoc
Genome-wide linkage scans were carried out using a multipoint variance components method
in white and black families of the NHLBI Hypertension Genetic Epidemiology Network
(HyperGEN) study to identify quantitative trait loci (QTLs) for pancreatic β-cell function and ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Fasting Insulin and Obesity-Related Phenotypes Are Linked to Chromosome 2p


VP Diego, HHH Göring, SA Cole, L Almasy, TD Dyer, J … - Diabetes, 2006 - Am Diabetes Assoc
To localize quantitative trait loci for insulin metabolism and obesity, genome scans/linkage analyses
were performed on >900 members of 32 extended families participating in phase 3 of the Strong
Heart Study, an investigation of the genetic and environmental determinants of ...
Cited by 4 - Related articles - BL Direct - All 7 versions

Genome-wide search for susceptibility genes to type 2 diabetes in West Africans: …


G Chen, A Adeyemo, J Zhou, Y Chen, H Huang, A … - Diabetes Research and …, 2007 - Elsevier
C-peptide is a substance that the pancreas releases into the circulation in equimolar amounts
to insulin and has demonstrated important physiological effects which relate to the vascular
field, in particular the microcirculation. For this analysis, we included 321 full and 36 half ...
Cited by 4 - Related articles - All 4 versions

Genome-wide scan for serum ghrelin detects linkage on chromosome 1p36 in …


VS VORUGANTI, HHH GÖRING, VP DIEGO, G CAI … - Pediatric …, 2007 - journals.lww.com
This study was conducted to investigate genetic influence on serum ghrelin and its relationship
with adiposity-related phenotypes in Hispanic children (n = 1030) from the Viva La Familia study
(VFS). Anthropometric measurements and levels of serum ghrelin were estimated and ...
Cited by 5 - Related articles - BL Direct - All 7 versions

Epistasis between type 2 diabetes susceptibility Loci on chromosomes 1q21-25 …


S Wiltshire, JT Bell, CJ Groves, C Dina, AT … - Annals of Human …, 2006 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 6 - Related articles - BL Direct - All 3 versions

Functional mapping of disease susceptibility loci using cell biology


PA Antinozzi, A Garcia-Diaz, C Hu, JE … - Proceedings of the …, 2006 - National Acad Sciences
In most genome-wide linkage studies, implication of a causative disease gene often requires
years of expanding the study to more families and finer mapping of the initially described
region. Even after such efforts, unobtainable sample sizes can be required to make ...
Cited by 6 - Related articles - BL Direct - All 9 versions

Heritability and genetic correlations of insulin sensitivity measured by the …


LJ Rasmussen-Torvik, JS Pankow, DR Jacobs Jr, … - Diabetic …, 2007 - pt.wkhealth.com
Results: Homeostasis model of insulin resistance (HOMA-IR) and fasting insulin were very highly
phenotypically and genetically correlated (r = 0.99 and r = 0.99). HOMA-IR and insulin sensitivity
measured with the euglycaemic clamp were only moderately genetically correlated (r = ...
Cited by 6 - Related articles - BL Direct - All 4 versions

A comparison of methods for intermediate fine mapping


C Papachristou, S Lin - Genetic epidemiology, 2006 - interscience.wiley.com
The arrival of highly dense genetic maps at low cost has geared the focus of linkage analysis
studies toward developing methods for placing putative trait loci in narrow regions with high
confidence. This shift has led to a new analytic scheme that expands the traditional two- ...
Cited by 7 - Related articles - BL Direct - All 3 versions

Linkage but not association of calpain-10 to type 2 diabetes replicated in northern …

- diabetesjournals.org
E Einarsdottir, S Mayans, K Ruikka, SA Escher, P … - Diabetes, 2006 - Am Diabetes Assoc
We present data from a genome-wide scan identifying genetic factors conferring susceptibility
to type 2 diabetes. The linkage analysis was based on 59 families from northern Sweden, consisting
of a total of 129 cases of type 2 diabetes and 19 individuals with impaired glucose ...
Cited by 8 - Related articles - BL Direct - All 7 versions


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