- ►diabetesjournals.org DA Cano, IC Rulifson, PW Heiser, LB Swigart, S … - Diabetes, 2008 - Am Diabetes Assoc Several studies have shown that the adult pancreas possesses a limited potential for β-cell regeneration
upon tissue injury. One of the difficulties in studying β-cell regeneration has been the lack of
a robust, synchronized animal model system that would allow controlled regulation of ... Cited by 15 - Related articles - BL Direct - All 3 versions
Y Bar, HA Russ, S Knoller, L Ouziel-Yahalom, S Efrat - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—In vitro expansion of β-cells from adult human islets could solve the tissue shortage
for cell replacement therapy of diabetes. Culture of human islet cells typically results in <16 cell
doublings and loss of insulin expression. Using cell lineage tracing, we demonstrated that ... Cited by 3 - Related articles - All 4 versions
M von Herrath, GT Nepom - Nature Immunology, 2009 - nature.com Type 1 diabetes is an immune-mediated disease in which pancreatic insulin-producing beta
cells are damaged and destroyed. Animal models have served a prominent function in the development
of the present ideas of pathogenesis and approaches to therapy. This commentary ... Cited by 4 - Related articles - All 3 versions
R Gallo, F Gambelli, B Gava, F Sasdelli, V Tellone … - Cell Death & …, 2007 - nature.com Cellular models and culture conditions for in vitro expansion of insulin-producing cells represent
a key element to develop cell therapy for diabetes. Initial evidence that human -cells could be
expanded after undergoing a reversible epithelial–mesenchymal transition has been ... Cited by 14 - Related articles - BL Direct - All 5 versions
DV SERREZE, MP MARRON, TP … - Annals of the New York …, 2007 - interscience.wiley.com Abstract : The mechanistic basis by which the H2 g7 major histocompatibility complex (MHC)
provides the primary risk factor for the development of T cell–mediated autoimmune type 1 diabetes
(T1D) in non-obese diabetic (NOD) mice involves contributions not only from the unusual ... Cited by 3 - Related articles - BL Direct - All 5 versions
GV Shah, A Muralidharan, M Gokulgandhi, K Soan, … - Journal of Biological …, 2009 - ASBMB Calcitonin, a neuroendocrine peptide, and its receptor are localized in the basal epithelium of
benign prostate but in the secretory epithelium of malignant prostates. The abundance of calcitonin
and calcitonin receptor mRNA displays positive correlation with the Gleason grade of ... Cited by 3 - Related articles - All 3 versions
Z Wang, Y Li, D Kong, S Banerjee, A Ahmad, AS Azmi, … - Cancer research, 2009 - AACR Pancreatic cancer (PC) is a highly aggressive malignant disease, which is ranked as the fourth
leading cause of cancer-related deaths in the United States, with 37,000 newly diagnosed cases
and 34,000 deaths per year in the United States (1). In recent years, novel treatment ... Cited by 4 - Related articles - All 4 versions
- ►diabetesjournals.org ZV Wang, J Mu, TD Schraw, L Gautron, JK Elmquist, BB … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Islet transplantations have been performed clinically, but their practical applications
are limited. An extensive effort has been made toward the identification of pancreatic β-cell stem
cells that has yielded many insights to date, yet targeted reconstitution of β-cell mass ... Cited by 4 - Related articles - All 4 versions
- ►unair.ac.id [PDF] MW Appleby, F Ramsdell - Curr Top Microbiol Immunol, 2008 - Springer Abstract The ability to rapidly and efficiently recognize and eliminate pathogens while sparing
normal self tissue is a hallmark of the mammalian immune system. When it fails, however, autoimmune
disease results. The genetic and environmental factors that control the process of making ... Cited by 4 - Related articles - All 4 versions
A Voulgari, A Pintzas - BBA-Reviews on Cancer, 2009 - Elsevier Epithelial–mesenchymal transition (EMT) is a key step during embryogenesis. Accumulating
evidence suggests a critical role in cancer progression, through which tissue epithelial cancers
invade and metastasise. Cell characteristics are highly affected during EMT, resulting in ... Cited by 5 - Related articles - All 2 versions
