LR Peterson, P Herrero, J McGill, KB Schechtman, Z … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—To test the hypotheses that in humans with type 1
diabetes, myocardial glucose and fatty acid metabolism can be manipulated by altering plasma
free fatty acid (FFA) and insulin levels, we quantified myocardial oxygen consumption ... Cited by 9 - Related articles - BL Direct - All 3 versions
D Gordin, M Rönnback, C Forsblom, O Heikkilä, M … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Augmentation index (AIx) and pulse wave velocity (PWV), both measures
of arterial stiffness, consti- tute risk factors for cardiovascular disease. Notably, hyper- glycaemia
during an acute cardiovascular event is associated with poor prognosis. The objective of ... Cited by 7 - Related articles - BL Direct - All 5 versions
P Herrero, J McGill, DS Lesniak, CS Dence, SW … - Journal of Nuclear …, 2008 - Springer Background. Our objective was to determine, in the hearts of women with type 1 diabetes mellitus
(T1DM), whether the fate of extracted glucose is altered and, if so, what the impact of dobutamine
is on myocardial substrate metabolism. In experimental models of T1DM, myocardial ... Cited by 3 - Related articles - All 3 versions
P Herrero, CS Dence, AR Coggan, Z Kisrieva- … - Journal of Nuclear …, 2007 - Soc Nuclear Med Lactate is a key myocardial energy source. Lactate metabolism is altered in a variety of
conditions, such as exercise and diabetes mellitus. However, to our knowledge, noninvasive
quantitative measurements of myocardial lactate metabolism have never been performed ... Cited by 5 - Related articles - BL Direct - All 3 versions
LD Monti, G Lucignani, C Landoni, RM Moresco, P … - Diabetes, 1995 - Am Diabetes Assoc Myocardial and whole-body glucose metabolism was assessed in 19 insulin-dependent diabetes
mellitus (IDDM) patients. A hyperglycemic clamp was performed 1) in the absence of insulin
at free fatty acid (FFA) levels of 1.0 mmol/l (test 1); 2) in the absence of insulin at low FFA ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►snmjournals.org KI Shoghi, RJ Gropler, T Sharp, P Herrero, N … - Journal of Nuclear …, 2008 - Soc Nuclear Med Diabetic cardiomyopathy is associated with abnormalities in glucose metabolism. We evaluated
myocardial glucose metabolism in a rodent model of type 2 diabetes, namely the Zucker diabetic
fatty (ZDF) rat, and validated PET measurements of glucose uptake against gene and ... Cited by 6 - Related articles - All 3 versions
- ►leidenuniv.nl [PDF] S Hammer - 2008 - openaccess.leidenuniv.nl Objectives: An association has been suggested between elevated plasma non-esterified fatty
acid (NEFA) levels, myocardial triglyceride (TG) accumulation and myocardial function. The objective
of the present study was to investigate the effects of an elevation of plasma NEFAs by a ... Related articles - View as HTML - All 3 versions
S Hammer, JT Jonker, HJ Lamb, RW van der Meer, W … - Myocardial Triglycerides - nve.nl Chapter 8 116 Summary Objectives: Patients with type 1 diabetes mellitus (DM1) suffer from
frequent episodes of hyper- glycemia and high plasma levels of non-esterified fatty acids
(NEFAs) despite insulin treatment. The aim of this study was to evaluate the effects of ... Related articles - View as HTML - All 2 versions
- ►diabetesjournals.org S Hammer, JT Jonker, HJ Lamb, RW van der Meer, … - Diabetes care, 2008 - Am Diabetes Assoc RESULTS—Mean insulin infusion rate was 45 ± 5 units at baseline, whereas it was 27 ± 5 units
during hyperglycemia (per 24 h, P < 0.001). Plasma glucose levels increased from 8.4 ± 0.6 to
15.9 ± 0.8 mmol/l (P < 0.001), and plasma levels of nonesterified fatty acids from 0.31 ± ... Related articles - All 6 versions
A Bashir, RJ Gropler - Cardiology Clinics, 2009 - Elsevier Flexibility in myocardial substrate metabolism for energy production is fundamental to cardiac
health. This loss in plasticity or flexibility leads to overdependence on the metabolism of an individual
category of substrates, with the predominance in fatty acid metabolism characteristic of ... Related articles - All 22 versions
