X Zhang, DCY Yeung, M Karpisek, D Stejskal … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Serum FGF21 levels in overweight/obese subjects were significantly
higher than in lean individuals. Serum FGF21 correlated positively with
adiposity, fasting insulin, and triglycerides but negatively with HDL ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►endojournals.org I Dostalova, P Kavalkova, D Haluzikova, Z … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Context: Fibroblast growth factor 19 (FGF19) and FGF21 are novel metabolic
regulators that improve insulin sensitivity and decrease adiposity in mice.
However, little is known about the nutritional regulation of these factors ... Cited by 9 - Related articles - All 3 versions
WW Chen, L Li, GY Yang, K Li, XY Qi, W Zhu, … - Experimental and clinical endocrinology & diabetes: …, 2008 - ncbi.nlm.nih.gov 1: Exp Clin Endocrinol Diabetes. 2008 Jan;116(1):65-8. Epub 2007 Oct 9.
Circulating FGF-21 levels in normal subjects and in newly ... Cited by 14 - Related articles - BL Direct - All 3 versions
W Wente, AM Efanov, M Brenner, A … - Diabetes, 2006 - Am Diabetes Assoc Fibroblast growth factor-21 (FGF-21) is a recently discovered metabolic
regulator. Here, we investigated the effects of FGF-21 in the pancreatic
β-cell. In rat islets and INS-1E cells, FGF-21 activated extracellular ... Cited by 56 - Related articles - BL Direct - All 4 versions
T Lundåsen, MC Hunt, LM Nilsson, S Sanyal, … - Biochemical and biophysical research communications, 2007 - Elsevier The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic
properties in animal models of diabetes and obesity. Using quantitative RT-PCR,
we here show that the hepatic gene expression of FGF21 is regulated by the ... Cited by 35 - Related articles - All 4 versions
Y Izumiya, HA Bina, N Ouchi, Y Akasaki, A … - FEBS letters, 2008 - Elsevier Fibroblast growth factor-21 (FGF21) functions as a metabolic regulator. The
FGF21 transcript is reported to be abundantly expressed in liver, but little is
known about the regulation of FGF21 expression in other tissues. In this ... Cited by 15 - Related articles - All 4 versions
T Coskun, HA Bina, MA Schneider, JD Dunbar … - Endocrinology, 2008 - Endocrine Soc Fibroblast growth factor 21 (FGF21) is a metabolic regulator that provides
efficient and durable glycemic and lipid control in various animal models.
However, its potential to treat obe- sity, a major health concern affecting ... Cited by 15 - Related articles - All 3 versions
C Gälman, T Lundåsen, A Kharitonenkov, HA … - Cell Metabolism, 2008 - Elsevier FGF21 is a critical metabolic regulator, pivotal for fasting adaptation and
directly regulated by PPARα in rodents. However, the physiological role of
FGF21 in man is not yet defined and was investigated in our study. Serum ... Cited by 17 - Related articles - All 4 versions
- ►endojournals.org A Kharitonenkov, VJ Wroblewski, A Koester, … - Endocrinology, 2007 - Endocrine Soc Fibroblast growth factor (FGF)-21 has been recently characterized as a potent
metabolic regulator. Systemic administration of FGF-21 reduced plasma glucose
and triglycerides to near normal levels in genetically compromised diabetic ... Cited by 59 - Related articles - BL Direct - All 4 versions
- ►aspetjournals.org ES Muise, B Azzolina, DW Kuo, M El- … - Molecular Pharmacology, 2008 - ASPET Adipose tissue is a metabolically responsive endocrine organ that secretes a
myriad of adipokines. Antidiabetic drugs such as peroxisome
proliferator-activated receptor (PPAR) agonists target adipose tissue gene ... Cited by 10 - Related articles - All 3 versions
