- ►diabetesjournals.org KJ Gaulton, CJ Willer, Y Li, LJ Scott, KN Conneely, AU … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—In a case-control study of 1,161 type 2 diabetic subjects
and 1,174 control Finns who are normal glucose tolerant, we genotyped 3,531 tagSNPs and
annotation-based SNPs and imputed an additional 7,498 SNPs, providing 99.9% ... Cited by 12 - Related articles - All 6 versions
- ►diabetesjournals.org SS Rich, JM Norris, JI Rotter - Diabetes, 2008 - Am Diabetes Assoc Diabetes, and particularly type 2 diabetes, is one of the most significant public health problems
facing Western civilization. Every day, 4,100 people in the US are diagnosed with diabetes. Of
those with diabetes, each day, 230 have their legs amputated, 120 are newly placed on ... Cited by 1 - Related articles - All 3 versions
[CITATION] Markov model for rapid haplotyping and genotype imputation in genome wide …
- ►spendocrinologia.org.pe [PDF] H Staiger, F Machicao, A Fritsche, HU Haring - Endocrine Reviews, 2009 - Endocrine Soc Type 2 diabetes mellitus is a complex metabolic disease that is caused by insulin resistance
and β-cell dysfunction. Furthermore, type 2 diabetes has an evident genetic component and
represents a polygenic disease. During the last decade, considerable progress was ... Related articles - All 4 versions
- ►umich.edu [PDF] KN Conneely - deepblue.lib.umich.edu Methods for large-scale genetic association studies ... A dissertation submitted in partial fulfillment
of the requirements for the degree of Doctor of Philosophy (Biostatistics) in The University of
Michigan 2008 ... Professor Michael L. Boehnke, Chair Associate Professor Gonçalo ... Related articles - View as HTML - All 2 versions
M Snyder, S Weissman, M Gerstein - Molecular Systems Biology, 2009 - pubmedcentral.nih.gov With the cost of DNA sequencing decreasing rapidly, it is likely that the genome sequences of
many individuals will be determined. In fact, if half of the individuals in industrialized countries
choose to have their genomes sequenced, then well over 500 million personal genome ... Cited by 1 - Related articles - All 4 versions
A Jablensky - Springer Abstract Schizophrenia is a complex disorder, whose phenotypic variation and likely extensive
genetic het- erogeneity is not adequately captured by current clinical classifications. Despite
a century of research, the field abounds in inconsistent empirical findings and con- ... Related articles
PJ Bilan, V Samokhvalov, A Koshkina, JD Schertzer, … - 2009 - Informa Pharma Science Obesity is associated with insulin resistance and increased risk for developing type 2
diabetes. Enlarged adipocytes develop resistance to the anti-lipolytic action of insulin. Elevated
levels of fatty acids in the plasma and interstitial fluids lead to whole-body insulin ... Related articles - All 5 versions
- ►cftwinsibstudy.com [PDF] SM Blackman, S Hsu, SE Ritter, KM Naughton, FA … - Diabetologia, 2009 - Springer Abstract Aims/hypothesis Insulin-requiring diabetes affects 25–50% of young adults with cystic
fibrosis (CF). Although the cause of diabetes in CF is unknown, recent heritability studies in CF
twins and siblings indicate that genetic modifiers play a substantial role. We sought to ... Related articles - All 3 versions
