- ►diabetesjournals.org [PDF] V Butty, C Campbell, D Mathis, C Benoist - Diabetes, 2008 - Am Diabetes Assoc Page 1. Genetic determinants of Type 1 DM progression Impact of diabetes
susceptibility loci on progression from pre-diabetes to ... Related articles - All 2 versions
- ►diabetesjournals.org V Butty, C Campbell, D Mathis, C Benoist - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The unfolding of type 1 diabetes involves a number of steps:
defective immunological tolerance, priming of anti-islet autoimmunity, and
destruction of insulin-producing β-cells. A number of genetic loci ... Cited by 4 - Related articles - All 5 versions
C Guja, L Guja, S Nutland, H Rance, M … - J. Cell. Mol. Med, 2004 - interscience.wiley.com Most cases of type 1 diabetes (T1DM) are due to an immune-mediated destruction
of the pancreatic beta cells, a process that is conditioned by multiple genes
and environmental factors. The main susceptibility genes are represented by ... Cited by 9 - Related articles - BL Direct - All 2 versions
[CITATION] Ionescu--Tirgoviste C
H Ueda, JM Howson, L Esposito, J Heward, H … - Savage DA, Maxwell AP, Carson DJ, Patterson CC, …, 2003 Cited by 4 - Related articles
[CITATION] lonescu-Tirgoviste C
D Smyth, JD Cooper, JE Collins, JM Heward, … - Savage DA, Dunger DB, Widmer B, Strachan DP, Ring … Cited by 3 - Related articles
LB Nielsen, HB Mortensen, F Chiarelli, R Holl … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 71–74 DOI 10.1007/s00125-005-0042-1 SHORT COMMUNICATION
LB Nielsen . HB Mortensen . F. Chiarelli . R. Holl . P. Swift . ... Cited by 11 - Related articles - BL Direct - All 5 versions
- ►endojournals.org MJ Redondo, S Babu, A Zeidler, T Orban, L Yu … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Objective: The objective of the study was to analyze whether HLA DQ alleles
influence the development of antiislet autoantibodies, the progression to T1DM
among autoantibody-positive relatives, or both. ... Design: The Diabetes ... Cited by 11 - Related articles - BL Direct - All 4 versions
[CITATION] Diabetes Incidence in Sweden Study Group; Swedish Childhood Diabetes Study Group. …
- ►nih.gov V Butty, M Roy, P Sabeti, W Besse, C Benoist, … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences The three members of the costimulatory receptor family, CD28, CTLA-4, and ICOS,
have complementary effects on T cell activation, and their balance controls the
overall outcome of immune and autoimmune responses. They are encoded in a ... Cited by 15 - Related articles - BL Direct - All 9 versions
AF Moore, JC Florez, 2008 - Annual Reviews Despite major advances in our knowledge of glycemic pathophysiology and the
availability of multiple therapeutic options to confront type 2 diabetes,
unraveling the complex link between genetic risk and environmental factors ... Cited by 17 - Related articles - BL Direct - All 3 versions