HQ Qu, SFA Grant, JP Bradfield, C Kim, E Frackelton, H … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Two European population samples were studied: 1)
one case-control cohort of 514 type 1 diabetic subjects and 2,027 control subjects and 2) one
family cohort of 483 complete type 1 diabetic case-parent trios (total 997 affected). A total ... Cited by 12 - Related articles - All 5 versions
C Brorsson, R Bergholdt, M Sjögren, S Eising, KM … - Molecular Genetics and …, 2008 - Elsevier Common complex diseases like type 1 diabetes (T1D) are believed to result from interactions
between multiple risk-conferring genes and environmental factors. The understanding of the
underlying factors of diabetes development is important for predicting who is at risk of ... Cited by 6 - Related articles - All 2 versions
H Gohlke, U Ferrari, K Koczwara, E … - The Review of …, 2008 - pubmedcentral.nih.gov It was recently shown that the major allele of the SLC30A8 (zinc transporter 8, ZnT8) single nucleotide
polymorphism (SNP) rs13266634 was associated with type 2 diabetes and with reduced insulin
secretion in non-diabetic relatives. Because of its role in beta-cell function, we ... Cited by 11 - Related articles - All 4 versions
[CITATION] The decline in circulating Slc30A8 autoantibodies track falling post-prandial C- …
JK Hertel, S Johansson, H Raeder, K Midthjell, V … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Recent genome-wide association studies performed in selected patients
and control participants have provided strong support for several new type 2 diabetes susceptibility
loci. To get a better estimation of the true risk conferred by these novel loci, we tested a ... Cited by 13 - Related articles - BL Direct - All 2 versions
JM Wenzlau, Y Liu, L Yu, O Moua, KT Fowler, S … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Sera from 224 subjects (53%) were reactive to Arg 325 probes, from 185 (44%)
to Trp 325 probes, and from 142 (34%) to Gln 325 probes. Sixty subjects reacted only with Arg
325 constructs, 31 with Trp 325 only, and 1 with Gln 325 only. The restriction to either Arg ... Cited by 12 - Related articles - All 4 versions
- ►nih.gov M Borowiec, R Thompson, C Powers, R Xu, T Dickey, A … - Diabetologia, 2007 - Springer Page 1. RESEARCH LETTER Mutations in the SLC30A8 gene are not a major cause
of MODYor other forms of early-onset, autosomal dominant type 2 diabetes M. Borowiec
& R. Thompson & C. Powers & R. Xu & T. Dickey & A. Doria ... Cited by 6 - Related articles - BL Direct - All 4 versions
C Murgia, C Devirgiliis, E Mancini, G Donadel, P … - Nutrition, Metabolism and …, 2009 - Elsevier As limited information was available on the biochemical properties of ZnT8 and on its endogenous
expression, we have raised a specific polyclonal antibody and immunostained protein
extracts, cell lines and tissue sections. We show that ZnT8 forms a very stable dimer that ... Cited by 7 - Related articles - All 14 versions
- ►jleukbio.org S Overbeck, P Uciechowski, ML Ackland, … - Journal of Leukocyte …, 2008 - Soc Leukocyte Biology Intracellular zinc homeostasis is strictly regulated by zinc binding proteins and zinc
transporters. In the present study, we quantified in a first global view the expression of all characterized
human zinc exporters (hZnT-1-9) in different leukocyte subsets in response to zinc ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►nih.gov SM Raj, JMM Howson, NM Walker, JD Cooper, DJ … - Diabetologia, 2009 - Springer Abstract Aims/hypothesis We used recently confirmed type 2 diabe- tes gene regions to investigate
the genetic relationship between type 1 and type 2 diabetes, in an average of 7,606 type 1 diabetic
individuals and 8,218 controls, providing >80% power to detect effects as small as an OR ... Cited by 1 - Related articles - All 4 versions