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Scholar Results 1 - 10 of about 101 related to van Hoek: Predicting type 2 diabetes based on polymorphisms from genome-wide association.... (0.11 sec) 

Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: …

- diabetesjournals.org
M van Hoek, A Dehghan, J Witteman, CM van … - Diabetes, 2008 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—We investigated 18 polymorphisms from recent GWA
studies on type 2 diabetes in the Rotterdam Study, a prospective,
population-based study among homogeneous Caucasian individuals of 55 years ...
Cited by 33 - Related articles - All 4 versions

Assessing the combined impact of 18 common genetic variants of modest effect sizes on type …


H Lango, CNA Palmer, AD Morris, E Zeggini, … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVES—Genome-wide association studies have dramatically increased the
number of common genetic variants that are robustly associated with type 2
diabetes. A possible clinical use of this information is to identify ...
Cited by 28 - Related articles - All 5 versions

Post genome-wide association studies of novel genes associated with type 2 diabetes show …


S Cauchi, D Meyre, E Durand, C Proença, M … - PloS one, 2008 - pubmedcentral.nih.gov
In the same French population analyzed in our previous GWA study (3,295 T2D and
3,595 NGT), strong associations with T2D were found for CDKAL1 (OR rs7756992 =
1.30[1.19–1.42], P = 2.3×10 −9 ), CDKN2A/2B (OR rs10811661 = ...
Cited by 21 - Related articles - All 7 versions

[CITATION] Diabetes Genetics Consortium, Palmer CN, Morris AD, Zeggini E, Hattersley AT, McCarthy MI …


H Lango - Diabetes, 2008
Cited by 8 - Related articles

Genotype score in addition to common risk factors for prediction of type 2 diabetes


JB Meigs, P Shrader, LM Sullivan, JB … - The New England Journal of Medicine, 2008 - nejm.highwire.org
From the General Medicine Division (JB Meigs, PS), the Department of Medicine
(JB Meigs, PS, JCF), and the Center for Human Genetic Research and Diabe- tes
Unit, Department of Medicine (JB McAteer, JCF), Massachusetts General ...
Cited by 43 - Related articles - All 3 versions

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study

- diabetesjournals.org
M Vaxillaire, J Veslot, C Dina, C Proença, S … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS— The GCK (Glucokinase) −30A allele was associated with increased
type 2 diabetes risk at the end of the follow-up study (adjusted OR 1.34 [95% CI
1.07–1.69]) under an additive model, as supported in independent French ...
Cited by 34 - Related articles - BL Direct - All 4 versions

The impact of genotype frequencies on the clinical validity of genomic profiling for …

- prsjournal.net
ACJW Janssens, R Moonesinghe, Q Yang, EW … - Genetics in Medicine, 2007 - journals.lww.com
Purpose: Single genetic variants in multifactorial disorders typically have
small effects, so major increases in disease risk are expected only from the
simultaneous exposure to multiple risk genotypes. We investigated the ...
Cited by 21 - Related articles - BL Direct - All 7 versions

Clinical risk factors, DNA variants, and the development of type 2 diabetes


V Lyssenko, A Jonsson, P Almgren, N Pulizzi, … - The New England Journal of Medicine, 2008 - nejm.highwire.org
From the Department of Clinical Sciences, Lund University, Malmö, Sweden (VL,
AJ, PA, GB, PN, LG); the University of Pisa, Pisa, Italy (NP); the Folkhalsan
Research Center (BI, TT) and Helsinki University Central Hospital and the ...
Cited by 58 - Related articles - All 4 versions

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 …

- diabetesjournals.org [PDF] 
N Grarup, CS Rose, EA Andersson, G Andersen … - Diabetes, 2007 - Am Diabetes Assoc
Page 1. Studies of Association of Variants Near the HHEX, CDKN2A/B, and IGF2BP2
Genes With Type 2 Diabetes and Impaired Insulin Release ...
Cited by 60 - Related articles - BL Direct - All 3 versions

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, …


N Grarup, G Andersen, NT Krarup, A … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS— Homozygous carriers of the minor diabetes risk G-allele of the
CDC123/CAMK1D rs12779790 showed an 18% decrease in insulinogenic index (95% CI
10–27%; P = 4 × 10 −5 ), an 18% decrease in corrected insulin response ...
Cited by 16 - Related articles - All 6 versions


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