G Fousteri, M von Herrath - Diabetes, 2008 - Am Diabetes Assoc Type 1 diabetes results from immune-mediated destruction of insulin-producing
β-cells of the pancreas. The disease manifests itself symptomatically when the
resident β-cells become unable to maintain normoglycemia. In human ... Related articles - BL Direct - All 3 versions
G Fousteri, M von Herrath - DIABETES, 2008 - Am Diabetes Assoc T ype 1 diabetes results from immune-mediated destruction of insulin-producing
-cells of the pancreas. The disease manifests itself symptom- atically when the
resident -cells become unable to maintain normoglycemia. In human ... Related articles
M KING, T Pearson, LD Shultz, J Leif, R … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2007 - interscience.wiley.com Abstract : The use of "humanized" mice represents an appealing translational
model for studies of the pathogenesis of immune-mediated diseases and for the
evaluation of potential therapeutics. The utility of humanized mice depends ... Cited by 5 - Related articles - BL Direct - All 8 versions
K Brands, E Colvin, LJ Williams, R Wang, RB … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The use of human fetal pancreatic tissue may provide a potential
source of transplantable β-cells as a therapy for type 1 diabetes. Human fetal
pancreas has a remarkable capacity to grow and differentiate in vivo and ... Cited by 7 - Related articles - BL Direct - All 4 versions
LD Shultz, T Pearson, M KING, L GIASSI, L … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2007 - interscience.wiley.com Abstract : There are many rodent models of autoimmune diabetes that have been
used to study the pathogenesis of human type 1 diabetes (T1D), including the
non-obese diabetic (NOD) mouse, the biobreeding (BB) rat, and the ... Cited by 9 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org P In't Veld, D Lievens, J De Grijse, Z Ling, B … - Diabetes, 2007 - Am Diabetes Assoc Antibodies against islet cell antigens are used as predictive markers of type 1
diabetes, but it is unknown whether they reflect an ongoing autoimmune process
in islet tissue. We investigated whether organs from adult donors that are ... Cited by 12 - Related articles - BL Direct - All 4 versions
B Hirshberg - Current Diabetes Reports, 2009 - Springer Introduction: Although it is well established that individuals with type 1
diabetes mellitus (T1DM) can minimize their risk for long-term complications by
maintaining near-normal blood glucose [1], it is equally well established ... Related articles - All 2 versions
B Hirshberg - Current Diabetes Reports, 2008 - Springer Introduction: Diabetic nephropathy occurs in 20% to 40% of patients with
diabetes and is the single lead- ing cause of end-stage renal disease. Mortality
is high in diabetic patients requiring dialysis. Among patients with ... Related articles - All 2 versions
- ►pubget.com [PDF] AE Butler, R Galasso, JJ Meier, R Basu, RA … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Type 1 diabetes is characterised by a deficit in beta
cell mass thought to be due to immune- mediated increased beta cell apoptosis.
Beta cell turnover has not been examined in the context of new-onset type 1 ... Cited by 20 - Related articles - BL Direct - All 3 versions
