PM Stewart, JW Tomlinson - Diabetes, 2009 - Am Diabetes Assoc An exciting era is upon us in terms of new therapies for patients with diabetes,
obesity, and metabolic syndrome. One such advance is the ability to selectively
manipulate tissue levels of glucocorticoids through targeted inhibition of ... Cited by 1 - Related articles - All 3 versions
JE McCutcheon, AS Fisher, E Guzdar, SA … - European Journal of Neuroscience, 2008 - interscience.wiley.com Genetic background affects animal phenotype and therefore is of particular
relevance to studies using genetically manipulated mice. Strain differences in
hypothalamic–pituitary–adrenocortical (HPA) axis activity may ... Cited by 5 - Related articles - BL Direct - All 3 versions
R Basu, DS Edgerton, RJ Singh, A … - Diabetes, 2006 - ncbi.nlm.nih.gov Eight dogs underwent combined hepatic/portal vein catheterization and infusion
of D4-cortisol in order to determine the relative contributions of the viscera
and liver to splanchnic cortisol production. D4-cortisol concentrations ... Cited by 5 - Related articles - BL Direct - All 3 versions
- ►ed.ac.uk [PDF] RH Stimson, J Andersson, R Andrew, DN … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE—11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) regenerates
cortisol from cortisone. 11β-HSD1 mRNA and activity are increased in vitro in
subcutaneous adipose tissue from obese patients. Inhibition of 11β-HSD1 is ... Cited by 5 - Related articles - All 6 versions
B Walker, J Seckl - International textbook of obesity. Chichester: John …, 2001 - ttdinhduong.org Cortisol is the principal glucocorticoid hormone in humans, contributing to
homeostatic regulation of basal metabolism and salt and water balance, and
modulating the response to stress. Normal adult human adrenal glands ... Cited by 6 - Related articles - View as HTML - All 3 versions
KA Hughes, SP Webster, BR Walker - Expert Opin. Investig. Drugs, 2008 - informahealthcare.com Background: Glucocorticoids such as cortisol are important regulators of fuel
metabolism during starvation and stress. Chronic glucocorticoid excess induces
obesity with multiple features of the metabolic syndrome. Objective: In ... Cited by 7 - Related articles - BL Direct - All 7 versions
- ►cjb.net JLW Yau, KM McNair, J Noble, D Brownstein, … - Journal of Neuroscience, 2007 - neuro.cjb.net Glucocorticoids are pivotal in the maintenance of memory and cognitive functions
as well as other essential physiological processes including energy metabolism,
stress responses, and cell proliferation. Normal aging in both rodents and ... Cited by 7 - Related articles - All 6 versions
R Sukhija, P Kakar, V Mehta, JL Mehta - The American journal of cardiology, 2006 - Elsevier Metabolic syndrome, with its attendant cardiovascular complications, is reaching
epidemic proportions worldwide; hence, there is intense interest in
understanding the pathogenesis of and developing therapy for these common ... Cited by 9 - Related articles - All 17 versions
R Basu, A Basu, M Grudzien, P Jung, P … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Ratios of arterial and portal vein D4 cortisol/cortisol total (0.06 ±
0.01 vs. 0.06 ± 0.01) and D4 cortisol/D3 cortisol (1.80 ± 0.14 vs. 1.84 ±
0.14) did not differ, indicating that no visceral cortisol production or ... Cited by 3 - Related articles - All 3 versions
AT Spijker, EF Van Rossum, E Hoencamp, RH … - Bipolar Disorders, 2009 - interscience.wiley.com Objectives: In affective disorders, dysregulation of the
hypothalamus-pituitary-adrenal (HPA) axis is a frequently observed phenomenon.
Subtle changes in glucocorticoid receptor (GR) functioning caused by ... Cited by 6 - Related articles - All 3 versions
