L Agius - Diabetes, 2009 - Am Diabetes Assoc Glucokinase (hexokinase IV) has a major role in the control of blood glucose
homeostasis because it is the predominant hexokinase expressed in the liver, has
a very high control strength on hepatic glucose disposal (1), and is the ... Related articles - All 4 versions
- ►physiology.org VA Payne, C Arden, AJ Lange, L Agius - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc The insulin-resistant Zucker fa/fa rat has elevated hepatic glycolysis and
activities of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2
(PFK2). The latter catalyzes the formation and degradation of fructose-2,6- ... Cited by 6 - Related articles - BL Direct - All 5 versions
L Agius - Biochemical Journal, 2008 - eng.auburn.edu Conversion of glucose into glycogen is a major pathway that contributes to the
removal of glucose from the portal vein by the liver in the postprandial state.
It is regulated in part by the increase in blood-glucose concentration in ... Cited by 10 - Related articles - View as HTML - All 5 versions
- ►physiology.org JS Shin, TP Torres, REL Catlin, EP Donahue, … - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc Effect of stimulation of glucokinase (GK) export from the nucleus by small
amounts of sorbitol on hepatic glucose flux in response to elevated plasma
glucose was examined in 6-h fasted Zucker diabetic fatty rats at 10 wk of ... Cited by 4 - Related articles - BL Direct - All 5 versions
[CITATION] DESIR Study Group: The common P446L polymorphism in GCKR inversely modulates fasting …
M Coghlan, B Leighton - Expert Opin. Investig. Drugs, 2008 - informahealthcare.com Type 2 diabetes is a chronic metabolic disease that adversely affects both the
quality and longevity of life. The disease is characterised by elevated blood
glucose (hyperglycaemia) that is associated with microvascular ... Cited by 12 - Related articles - BL Direct - All 6 versions
- ►physiology.org DV Chirieac, HL Collins, J Cianci, JD Sparks, … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Triglyceride-rich lipoprotein (TRL) production was studied in Zucker diabetic
fatty (ZDF) rats, a model of insulin-resistant type 2 diabetes progression. TRL
production was measured in vivo by blocking catabolism with Triton WR-1339. ... Cited by 15 - Related articles - All 4 versions
L Agius - Best Practice & Research Clinical Endocrinology & …, 2007 - Elsevier Type-2 diabetes is associated with impaired glucose clearance by the liver in
the postprandial state, and with elevated glucose production in the
post-absorptive state. New targets within the liver are currently being ... Cited by 17 - Related articles - All 17 versions
M Orho-Melander, O Melander, C Guiducci, P … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—We performed association studies in 12 independent
cohorts comprising >45,000 individuals representing several ancestral groups
(whites from Northern and Southern Europe, whites from the US, African ... Cited by 21 - Related articles - All 11 versions
