GA Rutter - Diabetes, 2009 - Am Diabetes Assoc Despite being a subject under investigation for more than 35 years (6), just how
the effects of glucose are achieved at the level of individual α-cells is still
disputed and has become an area of vigorous research in recent times ... Related articles - All 3 versions
- ►diabetesjournals.org AC Hauge-Evans, AJ King, D Carmignac, CC … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE— Somatostatin (SST) is secreted by islet δ-cells and by extraislet
neuroendocrine cells. SST receptors have been identified on α- and β-cells,
and exogenous SST inhibits insulin and glucagon secretion, consistent with ... Cited by 5 - Related articles - All 8 versions
- ►endojournals.org RM Luque, RD Kineman - Endocrinology, 2007 - Endocrine Soc It has been previously reported that male and female somatostatin (SST) knockout
mice (Sst–/–) release more GH, compared with Sst+/+ mice, due to enhanced
GH-secretory vesicle release. Endogenous SST may also regulate GH secretion ... Cited by 7 - Related articles - BL Direct - All 3 versions
SJ Bailey, MA Ravier, GA Rutter - Diabetes, 2007 - Am Diabetes Assoc The mechanism(s) by which glucose regulates glucagon secretion both acutely and
in the longer term remain unclear. Added to isolated mouse islets in the
presence of 0.5 mmol/l glucose, γ-aminobutyric acid (GABA) inhibited ... Cited by 10 - Related articles - BL Direct - All 7 versions
I Leclerc, E Fernadez-Millan, M Nyirenda, GA … - Diabet Med, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 1 - Related articles
- ►diabetesjournals.org N Quoix, R Cheng-Xue, L Mattart, Z Zeinoun, … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—In 0.5 mmol/l glucose, [Ca 2+ ] c oscillated in some -cells and was
basal in the others. Increasing glucose to 15 mmol/l decreased [Ca 2+ ] c by 30%
in oscillating cells and was ineffective in the others. -Cell I KATP was ... Cited by 1 - Related articles - All 3 versions
E Vieira, A Salehi, E Gylfe - Diabetologia, 2007 - Springer Abstract Aims/hypothesis The mechanisms by which glucose regu- lates glucagon
release are poorly understood. The present study aimed to clarify the direct
effects of glucose on the glucagon-releasing alpha cells and those effects ... Cited by 24 - Related articles - BL Direct - All 4 versions
YM Leung, I Ahmed, L Sheu, X Gao, M Hara, … - Endocrinology, 2006 - Endocrine Soc Glucose regulates pancreatic islet -cell glucagon secretion directly by its
metabolism to generate ATP in -cells, and indirectly via stimulation of
paracrine release of ß-cell secretory products, particularly insulin. How ... Cited by 21 - Related articles - All 4 versions
- ►cell.com P Rorsman, SA Salehi, F Abdulkader, M … - Trends in Endocrinology & Metabolism, 2008 - Elsevier Glucagon, secreted by the α-cells of the pancreatic islets, is the most
important glucose-increasing hormone of the body. The precise regulation of
glucagon release remains incompletely defined but has been proposed to ... Cited by 4 - Related articles - All 5 versions
