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Scholar Results 1 - 10 of about 101 related to Haffty: Racial differences in the incidence of BRCA1 and BRCA2 mutations in a cohort of early.... (0.28 sec) 

Racial differences in the incidence of BRCA1 and BRCA2 mutations in a cohort of early …

- nih.gov
BG Haffty, A Silber, E Matloff, J Chung, D … - British Medical Journal, 2006 - jmg.bmj.com
Results: Of the 200 patients tested, 131 (65%) had wild type mutations, 34 (17%)
had deleterious mutations, and 35 (18%) had variants of uncertain significance.
There were no significant differences between the white and African ...
Cited by 21 - Related articles - BL Direct - All 10 versions

BRCA1 and BRCA2 mutations in a study of African American breast cancer patients


T Pal, J Permuth-Wey, T Holtje, R Sutphen - Cancer Epidemiology Biomarkers & Prevention, 2004 - AACR
The spectrum of mutations in BRCA1 and BRCA2 among African Americans has not
been well characterized because most studies to date have been done in Caucasian
families. According to Myriad Genetic Laboratories, Inc., only ∼3% of ...
Cited by 23 - Related articles - BL Direct - All 7 versions

Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis …


R Nanda, LP Schumm, S Cummings, JD … - Jama, 2005 - Am Med Assoc
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Cited by 65 - Related articles - BL Direct - All 4 versions

Prevalence of pathogenic BRCA1 mutation carriers in 5 US racial/ethnic groups


EM John, A Miron, G Gong, AI Phipps, A … - Jama, 2007 - Am Med Assoc
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Cited by 37 - Related articles - BL Direct - All 3 versions

BRCA1 variants in a family study of African-American and Latina women


R McKean-Cowdin, H Spencer Feigelson, LY … - Human genetics, 2005 - Springer
Abstract We sequenced the entire coding region of BRCA1 to improve our
understanding of the frequency and nature of BRCA1 variants in African-American
and Latina women identified from a multiethnic cohort in Los Angeles, ...
Cited by 13 - Related articles - All 4 versions

Complete allelic analysis of BRCA1 and BRCA2 variants in young Nigerian breast cancer …

- bmj.com
JD Fackenthal, L Sveen, Q Gao, EK Kohlmeir … - British Medical Journal, 2005 - jmg.bmj.com
Breast cancer is a leading cause of cancer deaths among women, and is expected
to claim the lives of nearly 40 000 individuals in the USA each year (American
Cancer Society Breast Cancer Facts and Figures 2003–2004). Only 5–10% ...
Cited by 18 - Related articles - All 6 versions

Breast cancer genetics in African Americans


O Olopade, J Fackenthal, G Dunston, M … - CA A Cancer Journal for Clinicians - interscience.wiley.com
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degraded, the site should continue to be functional. We recommend using the ...
Cited by 68 - Related articles - BL Direct - All 4 versions

Prevalence of BRCA mutations and founder effect in high-risk Hispanic families

- angrylapdog.com
JN Weitzel, V Lagos, KR Blazer, R Nelson, C … - Cancer Epidemiology Biomarkers & Prevention, 2005 - AACR
Results: Mean age at diagnosis was 37 years (range = 23-59) for the 89 (81%)
probands with invasive breast cancer. Overall, 34 (30.9%) had deleterious
mutations (25 in BRCA1, 9 in BRCA2), 25 (22.7%) had one or more ...
Cited by 40 - Related articles - BL Direct - All 5 versions

Inherited BRCA2 mutations in African Americans with breast and/or ovarian cancer: a study …


Y Kanaan, E Kpenu, K Utley, L Adams- … - Human genetics, 2003 - Springer
Abstract In order to identify the spectrum of BRCA2 mu- tations in African
Americans, breast or ovarian cancer pa- tients from 74 independent families at
elevated risk of germline mutations were investigated. The entire coding ...
Cited by 10 - Related articles - BL Direct - All 3 versions

Protein truncating BRCA1 and BRCA2 mutations in African women with pre-menopausal …


Q Gao, CA Adebamowo, J Fackenthal, S Das, … - Human genetics, 2000 - Springer
In populations indigenous to the African tropics, breast cancer has been
considered to be a rare disease, predomi- nantly afflicting young women.
However, the Interna- tional Agency of Research on Cancer Bulletins and ...
Cited by 22 - Related articles - BL Direct - All 3 versions


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