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Drugs five years later: bromocriptine


MLEE VANCE, WS EVANS, MO … - Annals of internal …, 1984 - Am Coll Physicians
Bromocriptine, a specific dopamine receptor agonist, has been used for the treatment of various
hyperprolactinemic conditions and as adjunctive therapy for acromegaly (with or without concomitant
hyperprolactinemia) and Parkinson's disease. Bromocriptine is extremely effective in ...
Cited by 64 - Related articles - All 3 versions

Withdrawal of bromocriptine after long-term therapy for macroprolactinomas: effect …


JW Van't Verlaat, RJM Croughs - Obstetrical & Gynecological Survey, 1991 - journals.lww.com
566 Obstetrical and Gynecological Survey vaginal bleeding, ranging between 10 and 22
days. Not only might this limit patient accepta- bility of this form of treatment, it also suggests that
hormonal alterations are not limited to a decrease in androgen synthesis.—Ed.) ...
Cited by 48 - Related articles - All 5 versions

Resistance to cabergoline as compared with bromocriptine in hyperprolactinemia: …

- endojournals.org
A Di Sarno, ML Landi, P Cappabianca, F Di … - Journal of Clinical …, 2001 - Endocrine Soc
After 24 months, PRL normalization and tumor shrinkage after CAB and BRC treatments,
respectively, were obtained in 82.1% and 46.4% of macroprolactinomas (P < 0.001) and in
90% vs. 56.8% of microprolactinomas (P < 0.001). The median doses of CAB and BRC ...
Cited by 88 - Related articles - BL Direct - All 8 versions

The natural history of untreated hyperprolactinemia: a prospective analysis


J Schlechte, K Dolan, B Sherman, F Chapler, A … - Journal of Clinical …, 1989 - Endocrine Soc
This report describes the results of a long term prospective study of 30 women with hyperprolactinemia
who were not treated and who underwent yearly clinical, hormonal, and radiographic evaluation
for an average of 5.2 yr (range 3–7 yr). At entry into the study 18 women had amenorrhea, ...
Cited by 125 - Related articles - All 3 versions

The natural history of untreated microprolactinomas.


DA Sisam, JP Sheehan, LR Sheeler - Fertility and sterility, 1987 - ncbi.nlm.nih.gov
The development of radioimmunoassay (RIA) for prolactin (PRL) and sensitive high-resolution
computed tomography (HRCT) has resulted in documentation of large numbers of microprolactinomas
(microPRL). To try to define the rate and prevalence of tumor growth, the authors ...
Cited by 71 - Related articles - All 3 versions

Long-term follow-up of prolactinomas: normoprolactinemia after bromocriptine …

- endojournals.org
VQ Passos, JJS Souza, NRC Musolino, MD … - Journal of Clinical …, 2002 - Endocrine Soc
Bromocriptine (BRC) and other dopamine agonist drugs are the first-choice treatment for
prolactinomas. However, the major disadvantage is the need for prolonged therapy. We retrospectively
studied 131 patients [62 microprolactinoma (MIC), 69 macroprolactinoma (MAC)], who ...
Cited by 71 - Related articles - BL Direct - All 7 versions

Effect of dopamine agonist withdrawal after long-term therapy in prolactinomas. …


DG Johnston, K Hall, P Kendall-Taylor, D Patrick, M … - Lancet, 1984 - ncbi.nlm.nih.gov
The clinical, radiological, and biochemical effects of dopamine agonist withdrawal after
long-term treatment were investigated in seven women and eight men who had been treated
for prolactinomas for 1.5 to 7 (mean 3.7) years. Before treatment, serum prolactin ...
Cited by 74 - Related articles - All 4 versions

Long-term treatment of hyperprolactinaemia with bromocriptine: effect of drug …


C Wang, KSL Lam, JTC Ma, T Chan, MY Liu, … - Clin …, 1987 - interscience.wiley.com
Fifty-one patients with hyperprolactinaemia (23 with macroadenoma, 23 with
microadenoma, and five with idiopathic hyperprolactinaemia) were treated with bromocriptine
for 2-12 years (4.9 ± 2.9 years, mean ± SD). During therapy, the serum PRL levels were ...
Cited by 42 - Related articles - All 4 versions

Follow-up of patients with prolactinomas after discontinuation of long-term therapy …


A Zarate, ES Canales, C Cano, CJ Pilonieta - Acta Endocrinologica, 1983 - EFES
Abstract. The effects of bromocriptine discontinuation after a 2 year course of therapy on prolactin
(Prl) serum levels and the radiological size of the sella turcica were investigated in 16 women
with amenorrhoea-galactorrhoea due to prolactinoma. During therapy, all but 2 patients ...
Cited by 36 - Related articles - All 5 versions

Bromocriptine treatment of microprolactinomas: evidence of stable prolactin …


P Moriondo, P Travaglini, M Nissim, A Conti, … - The Journal of clinical …, 1985 - ncbi.nlm.nih.gov
Thirty-six women with PRL-secreting pituitary microadenomas [mean PRL, 114 +/- 12.5 (+/-
SE) ng/ml] were treated with bromocriptine (BRC; 2.5-10 mg/day) for 12 months. During BRC
treatment, serum PRL decreased in all patients. After termination of treatment, mean ...
Cited by 37 - Related articles


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