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Scholar Results 1 - 10 of about 101 related to MEYER: Optimizing metoclopramide control of cisplatin-induced emesis. (0.10 sec) 

Optimizing metoclopramide control of cisplatin-induced emesis


BR MEYER, M LEWIN, DE DRAYER, M … - Annals of internal …, 1984 - Am Coll Physicians
Using an original high-pressure liquid chromatographic assay, we measured serum levels of
metoclopramide and defined a concentration-response relationship for metoclopramide control
of cisplatin-induced emesis. Using a metoclopramide regimen of 2 mg/kg body weight ...
Cited by 52 - Related articles - All 3 versions

High dose metoclopramide-preliminary pharmacokinetic studies.

- nih.gov [PDF] 
WD Taylor, DN Bateman - British Journal of Clinical …, 1983 - pubmedcentral.nih.gov
Nausea and vomiting are amongst the most trouble- some adverse effects of cytotoxic drug therapy
and in some cases may be so intolerable that patients refuse further treatment. Many anti-emetic
drugs have been used to try to prevent these reactions but most are, at best, only ...
Cited by 16 - Related articles - All 3 versions

The relationship between steady state metoclopramide levels and control of …

- nih.gov [PDF] 
DJ Kerr, J Graham, RG Blackie, E … - British Journal of …, 1985 - pubmedcentral.nih.gov
Adjepon-Yamoah, K. K., Woolhouse, NM & Pres- cott, L. F. (1985). The effect of chloroquine on
paracetamol kinetics. Br. J. clin. Pharmac. (in press). Bratton, AC & Marshall, EK (1939). A new
coupling component for sulphanilamide deter- mination. J. biol. Chem., 128, 537-550. ...
Cited by 9 - Related articles - All 3 versions

Optimising antiemesis in cancer chemotherapy: efficacy of continuous versus …

- nih.gov [PDF] 
PS Warrington, SG Allan, MA Cornbleet, JS … - British Medical Journal, 1986 - bmj.com
Page 1. doi:10.1136/bmj.293.6558.1334 1986;293;1334-1337 Br Med J (Clin Res
Ed) C Leonard PS Warrington, SG Allan, MA Cornbleet, JS MacPherson, JF Smyth
and R induced by cisplatin. infusion of high dose metoclopramide ...
Cited by 24 - Related articles - All 6 versions

Clinical pharmacokinetics of high-dose metoclopramide in cancer patients …

- ascopubs.org [PDF] 
JE McDermed, JL Cohen, C Joseph, SB … - Journal of Clinical …, 1985 - jco.ascopubs.org
H IGH-DOSE intravenous (IV) metoclopra- mide (Reglan, AH Robins, Richmond, Va) has been
shown to be effective in preventing chemotherapy-induced nausea and emesis,'-3 but optimal
results are not always achieved in cispla- tin-treated patients receiving the standard high- ...
Cited by 10 - Related articles - All 9 versions

Intravenous metoclopramide. An effective antiemetic in cancer chemotherapy


SB Strum, JE McDermed, RW Opfell, LP Riech - JAMA, 1982 - Am Med Assoc
An open-label clinical trial was conducted to test the safety and efficacy of intravenous metoclopramide
monohydrochloride in preventing chemotherapy-induced nausea and vomiting. Thirty-eight patients
received a total of 83 assessable courses of chemotherapy with cisplatin alone or in ...
Cited by 74 - Related articles - All 2 versions

Metoclopramide kinetics at high-dose infusion rates for prevention of cisplatin- …


R Saller, D Hellenbrecht, L Briemann, A Hellstern, … - Clinical Pharmacology & …, 1985 - nature.com
Eleven male subjects aged 24 to 58 yr received cisplatin, 90 to 120 mg/m 2 iv, in combination
with other cytostatic drugs such as doxorubicin HC1 and bleomycin. To prevent emesis, two
high-dose metoclopramide regimens were started 2 hr before cytostatic therapy. Regimen ...
Cited by 15 - Related articles - All 3 versions

Pharmacokinetics and efficacy of high-dose metoclopramide given by continuous …

- nih.gov [PDF] 
WB Taylor, SJ Proctor, DN Bateman - British Journal of Clinical …, 1984 - pubmedcentral.nih.gov
Page 1. Br. J. clin. Pharmac. (1984), 18, 679-684 Pharmacokinetics and efficacy of
high-dose metoclopramide given by continuous infusion for the control of cytotoxic
drug-induced vomiting WENDY B. TAYLOR', S. J. PROCTOR2 ...
Cited by 20 - Related articles - All 3 versions

High-dose dexamethasone for prevention of cis-platin-induced vomiting


MS Aapro, DS Alberts - Cancer Chemotherapy and Pharmacology, 1981 - Springer
Summary. Severe, debilitating nausea and vomiting are seen in almost 100% of patients treated
with cis-platinum. These side-effects can be so severe and prolonged as to preclude therapy
in a large number of patients. Commonly used antiemetics have had only limited success ...
Cited by 61 - Related articles - All 2 versions

[CITATION] Impairment of recall improves tolerance of cytotoxic chemotherapy.


ML Friedlander, K Sims, JH Kearsley - Lancet, 1983 - ncbi.nlm.nih.gov
1: Lancet. 1983 Sep 17;2(8351):686. Impairment of recall improves tolerance of
cytotoxic chemotherapy. Friedlander ML, Sims K, Kearsley JH. Publication Types:
Clinical Trial; Letter; Randomized Controlled Trial. Mesh Terms ...
Cited by 6 - Related articles - All 2 versions


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