DA Ahlquist, DB McGill, S Schwartz, WF … - Annals of internal …, 1984 - Am Coll Physicians HemoQuant, an assay based on heme-derived porphyrin, quantifies both total fecal hemoglobin
and that fraction already converted to porphyrin by gut flora (the intestinal converted
fraction). Recovery by HemoQuant of blood added to stools exceeded 99% and was not ... Cited by 48 - Related articles - All 5 versions
- ►clinchem.org [PDF] S Schwartz, J Dahl, M Ellefson, D Ahlquist - Clinical Chemistry, 1983 - Am Assoc Clin Chem We describe a new, specific, quantitative method for fecal blood, based on conversion of nonfluorescing
heme to fluorescing porphyrins, that obviates serious deficiencies inherent in currently used
tests. A two-reagent system is used to determine the two hemoglobin-related fractions that ... Cited by 86 - Related articles - All 4 versions
DA Ahlquist, DB McGill, S Schwartz, WF … - New England Journal …, 1985 - content.nejm.org We tested HemoQuant, a quantitative assay of fecal blood based on the fluorescence of
heme-derived porphyrin, in 106 healthy volunteers, 170 patients with gastrointestinal symptoms
but with normal diagnostic studies, 44 patients with gastrointestinal cancer, 75 patients ... Cited by 115 - Related articles - All 4 versions
M Goldschmiedt, DA Ahlquist, HS Wieand, DB … - Digestive Diseases and …, 1988 - Springer Hemoglobin-heme is variably converted to porphyrin during enterocolic transit. This intestinal
converted fraction, as measured by HemoQuant, was elevated as a predictor of the occult bleeding
site in 152 patients with discrete lesions. The intestinal converted fraction, expressed as ... Cited by 16 - Related articles - All 3 versions
S Schwartz, M Ellefson - Gastroenterology, 1985 - ncbi.nlm.nih.gov Blood, meat, or fish, or any combination thereof, were ingested by 9 normal volunteers to permit
studies of the contained hemes during total gastrointestinal transit. Quantitative analysis of ingested
heme and of fecal heme and its degradation products was made possible by a new ... Cited by 39 - Related articles - All 4 versions
GH Barrows, RM Burton, DD Jarrett, GG … - American journal of …, 1978 - ncbi.nlm.nih.gov Current methods for testing stool samples for hemoglobin utilize peroxidase oxidation of chemical
indicators such as guaiac or benzidine. These tests have frequent false-positive and false-negative
results, complicating random screening for occult gastrointestinal bleeding. The authors ... Cited by 47 - Related articles - All 2 versions
[CITATION] Faecal lactoferrin, a novel marker of colorectal cancer in rats: A longitudinal in vivo …
JR Stroehlein, VF Fairbanks, VL Go, WF … - Mayo Clinic …, 1976 - ncbi.nlm.nih.gov Stoll samples mixed with 0 to 38 mg of hemoglobin per gram of stool were tested for occult blood
by the Hemoccult (HO) method when fresh and after storage for 1 to 14 days. The intensity of
the HO reaction in fresh stool samples was directly related to the hemoglobin ... Cited by 38 - Related articles
… AHLQUIST, S SCHWARTZ, J ISAACSON, M … - Annals of internal …, 1988 - Am Coll Physicians Despite widespread fecal blood testing, the technique of gathering stool for sampling has remained
uncontrolled. We sought to describe how patients have contended with this awkward step, to
study artifact caused by toilet water, and to construct a collection device that prevents ... Cited by 21 - Related articles - All 4 versions
A CA - CA A Cancer Journal for Clinicians - interscience.wiley.com An immunochemical test for fecal occult blood was developed for use in colon cancer
screening. The test employs high titer monospecific antisera to intact human hemoglobin in a
radial immunodiffusion assay. Patient smears on specially treated filter paper allow ... Cited by 70 - Related articles - All 2 versions
