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Scholar Results 1 - 10 of about 101 related to BROWNLEE: Nonenzymatic glycosylation and the pathogenesis of diabetic complications. (0.11 sec) 

Nonenzymatic glycosylation and the pathogenesis of diabetic complications


M BROWNLEE, H VLASSARA, A CERAMI - Annals of internal medicine, 1984 - Am Coll Physicians
Glucose chemically attaches to proteins and nucleic acids without the aid of
enzymes. Initially, chemically reversible Schiff base and Amadori product
adducts form in proportion to glucose concentration. Equilibrium is reached ...
Cited by 599 - Related articles - All 4 versions

Accelerated age-related browning of human collagen in diabetes mellitus

- pnas.org [PDF] 
VM Monnier, RR Kohn, A Cerami - Proceedings of the National Academy of Sciences, 1984 - National Acad Sciences
Page 1. Proc. Nati. Acad. Sci. USA Vol. 81, pp. 583-587, January 1984 Medical Sciences
Accelerated age-related browning of human collagen in diabetes mellitus ...
Cited by 402 - Related articles - All 9 versions

Relation between complications of type I diabetes mellitus and collagen-linked fluorescence


VM Monnier, V Vishwanath, KE Frank, CA … - New England Journal of Medicine, 1986 - content.nejm.org
Nonenzymatically glycosylated proteins gradually form fluorescent cross-linked
protein adducts--a process termed "browning." The rate of this reaction
increases with the glucose concentration. Assaying for the presence of ...
Cited by 356 - Related articles - All 3 versions

Aging of proteins: isolation and identification of a fluorescent chromophore from the reaction …

- pnas.org [PDF] 
S Pongor, PC Ulrich, FA Bencsath, A Cerami - Proceedings of the National Academy of Sciences, 1984 - National Acad Sciences
Page 1. Proc. Natl. Acad. Sci. USA Vol. 81, pp. 2684-2688, May 1984
Biochemistry Aging of proteins: Isolation and identification ...
Cited by 219 - Related articles - All 8 versions

Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking


M Brownlee, H Vlassara, A Kooney, P Ulrich, … - Science, 1986 - sciencemag.org
REFERENCES AND NOTES 1. S. J. Tzartos and JM Lindstrom, Proc. Natl. Acad. Sci.
USA 77, 755 (1980). 2. S. J. Tzartos, DE Rand, BL Einarson, J. M. Lindstrom, J.
Biol. Cbem. 256, 8635 (1981). 3. LW Swanson ct at., Pmc. Nati. Acad. Sci. ...
Cited by 732 - Related articles - All 5 versions

Non-enzymatic glycosylation and the chronic complications of diabetes: an overview


L Kennedy, JW Baynes - Diabetologia, 1984 - Springer
Even before the introduction of insulin therapy in 1922, retinopathy, neuropathy
and proteinuria had all been described in association with diabetes mellitus.
How- ever, as the use of insulin has permitted long-term sur- vival of ...
Cited by 196 - Related articles - All 3 versions

[CITATION] Advanced glycosylation end products in tissue and the biochemical basis of diabetic …


M Brownlee, A Cerami, H Vlassara - New England Journal of Medicine, 1988 - content.nejm.org
Original Article from The New England Journal of Medicine -- Advanced glycosylation
end products in tissue and the biochemical basis of diabetic complications.
Cited by 1568 - Related articles - All 3 versions

Nonenzymatic browning in vivo: possible process for aging of long-lived proteins


VM Monnier, A Cerami - Science, 1981 - sciencemag.org
The incubation of lens proteins with reducing sugars leads to the formation of
fluorescent yellow pigments and cross-like similar to those reported in aging
and cataractous human lenses. Called nonenzymatic browning or the Maillard ...
Cited by 420 - Related articles - All 3 versions

Structure elucidation of a senescence cross-link from human extracellular matrix. Implication …

- jbc.org [PDF] 
DR Sell, VM Monnier - Journal of Biological Chemistry, 1989 - ASBMB
Page 1. THE JOURNAL 0 1989 by The American Society for Biochemistry and Molecular
Biology, Inc OF BIOLOGICAL CHEMISTRY Vol. 264, No . 36. ...
Cited by 659 - Related articles - All 3 versions

Covalent attachment of soluble proteins by nonenzymatically glycosylated collagen. Role in …

- rupress.org [PDF] 
M Brownlee, S Pongor, A Cerami - Journal of Experimental Medicine, 1983 - jem.rupress.org
Hyperglycemia appears to be the major risk factor for the development of
diabetic microvascular disease (1-3). However, the sequence of events leading
from abnormal glucose homeostasis to irreversible tissue damage remains to ...
Cited by 106 - Related articles - All 4 versions


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