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Scholar Results 1 - 10 of about 101 related to HENNESSEY: The equivalency of two L-thyroxine preparations. (0.10 sec) 

The equivalency of two L-thyroxine preparations


JV HENNESSEY, KD BURMAN, L … - Annals of internal …, 1985 - Am Coll Physicians
Differences in blood levels of thyroid hormones have been reported when patients taking synthetic
L-thyroxine were shifted from one manufactured form of the hormone to another. Because recent
formulation changes have rendered these earlier data obsolete, we did a crossover study ...
Cited by 24 - Related articles - All 3 versions

A study in normal human volunteers to compare the rate and extent of …


JA Berg, GH Mayor - The Journal of Clinical Pharmacology, 1992 - jclinpharm.highwire.org
Page 1. http://www.jclinpharm.org Pharmacology The Journal of Clinical 1992; 32; 1135 J. Clin.
Pharmacol. JA Berg and GH Mayor Synthroid and Levoxine A study in normal human volunteers
to compare the rate and extent of levothyroxine absorption from ...
Cited by 14 - Related articles - BL Direct - All 5 versions

Oral thyroxine: variation in biologic action and tablet content


CT SAWIN, MI SURKS, M LONDON, C … - Annals of internal …, 1984 - Am Coll Physicians
Thirty-two patients with primary hypothyroidism were given oral thyroxine as Levothroid or Synthroid
to see if the two preparations had similar effects. The serum thyroxine was used as an index
of bioavailability and the serum thyrotrophin as an index of biologic activity. The serum ...
Cited by 19 - Related articles - All 3 versions

Assessment of interchangeability of two brands of levothyroxine preparations with …


DA Escalante, N Arem, R Arem - The American journal of medicine, 1995 - Elsevier
Twenty-three of the 31 patients with long-standing primary hypothyroidism (6 men, 25
women; age range 30 to 71 years, mean 47.2 ± 2.2 SEM) were switched from Synthroid to Levoxine
(group 1) and the remaining patients from Levoxine to Synthroid (group 2). After ...
Cited by 15 - Related articles - All 6 versions

Comparative bioavailability of two oral L-thyroxine formulations after multiple dose …


M Vaisman, LD Spina, LF Eksterman, MJ dos … - Arzneimittel- …, 2001 - ncbi.nlm.nih.gov
The aim of the present study was to evaluate the bioequivalence and therapeutic equivalence
of the two most commonly prescribed L-thyroxine (monsodium L-thyroxine hydrate, CAS
25416-65-3) formulations in Brazil in patients treated for hypothyroidism. Twenty-four ...
Cited by 6 - Related articles - BL Direct - All 3 versions

[CITATION] Bioequivalence of levothyroxine preparations: shortcomings and implications of a …


L Wartofsky - The Endocrinologist, 1997
Cited by 9 - Related articles

Levothyroxine: therapeutic use and regulatory issues related to bioequivalence


L Wartofsky - eop, 2002 - informahealthcare.com
Levothyroxine is the overwhelming choice of clinicians for the treatment of hypothyroidism and
for the suppression of goitre and thyroid nodules in selected cases. The monitoring of serum
levels of thyroid stimulating hor- mone is necessary for appropriate dosage adjustment of ...
Cited by 11 - Related articles - All 4 versions

Levothyroxine a New Drug? Since When? How Could That Be?


JV Hennessey - Thyroid, 2003 - liebertonline.com
THE FOOD AND DRUG ADMINISTRATION (FDA) announced that orally administered drug products
containing levothyroxine sodium were new drugs on Thursday August 14, 1997 (1). My world
did not shake, quiver or turn upside down (but it should have). If I had been paying ...
Cited by 12 - Related articles - BL Direct - All 2 versions

Bioäquivalenz eines Kombinationspräparates aus Levothyroxin und Jodid im …


G Förster, C Hansen, F Mörsch, K Al-Hakim, J Beyer, G … - Medizinische Klinik, 1998 - Springer
Medizinisehe Klinik 1998;93:401-6 (Nr, 7), 9 Urban & Vogd, M™ ... Bio/iquivalenz eines
Kombinationspr/iparates aus Levothyroxin und Jodid im Vergleich zum Monopr/iparat Levothyroxin
... Gregor F/Srster, Christiane Hansen, Frederike M6rsch, Kafim A1-Hakim, J™ Beyer, ...
Cited by 4 - Related articles

Limitations of Levothyroxine Bioequivalence Evaluation: Analysis of An Attempted …


GH Mayor, T Orlando, NM Kurtz - American journal of therapeutics, 1995 - ncbi.nlm.nih.gov
The relative bioavailability and therapeutic comparability of four levothyroxine products (two
proprietary and two nonbranded) were determined in an open-label, block-randomized,
four-way crossover trial with no washout periods in 24 presumed hypothyroid ambulatory ...
Cited by 16 - Related articles


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