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Scholar Results 1 - 10 of about 101 related to GALE: Chronic lymphocytic leukemia: recent advances in biology and treatment. (0.14 sec) 

Chronic lymphocytic leukemia: recent advances in biology and treatment


RP GALE, KA FOON - Annals of internal medicine, 1985 - Am Coll Physicians
Chronic lymphocytic leukemia is a hematologic neoplasm characterized by
proliferation and accumulation of mature-appearing lymphocytes. Most cases
involve a clonal proliferation of B lymphocytes. The cells typically have ...
Cited by 117 - Related articles - All 5 versions

Chlorambucil pharmacokinetics and DNA binding in chronic lymphocytic leukemia …

- aacrjournals.org [PDF] 
BB Bank, D Kanganis, LF Liebes, R Silber - Cancer Research, 1989 - AACR
Chlorambucil (CLB) uptake by chronic lymphocytic leukemia lympho cytes was
studied using a radiometrie and a newly developed high- performance liquid
chromatography assay. CLB labeled with 14Cin either the chloroethyl group ...
Cited by 29 - Related articles - All 3 versions

The Uptake and Utilization of Chlorambucil by Lymphocytes from Patients with Chronic …

- nih.gov [PDF] 
BT Hill, KR Harrap - British Journal of Cancer, 1972 - pubmedcentral.nih.gov
]DIFFERENCES in the utilization of chlorambucil following its uptake by cells in
vitro have been demonstrated using an experimental animal tumour system (Harrap
and Hill, 1970): cells of a drug- resistant strain of the Yoshida ascites ...
Cited by 11 - Related articles - All 2 versions

[CITATION] The selectivity of action of alkylating agents and drug resistance. 3. The uptake and …


KR Harrap, BT Hill - Biochemical pharmacology, 1970 - ncbi.nlm.nih.gov
1: Biochem Pharmacol. 1970 Jan;19(1):209-17. The selectivity of action of
alkylating agents and drug resistance. 3. The uptake and ...
Cited by 14 - Related articles

Lack of drug-induced DNA cross-links in chlorambucil-resistant Chinese hamster ovary cells

- aacrjournals.org [PDF] 
BZ Jiang, BB Bank, YH Hsiang, T Shen, M … - Cancer Research, 1989 - AACR
Chlorambucil (CLB) is an alkylating agent commonly used in the treatment of
several neoplastic disorders. The mechanisms underlying resistance to this drug
are not fully defined. We used the DNA alkaline elution technique to study ...
Cited by 15 - Related articles - All 2 versions

[CITATION] Studies on the transport and cellular distribution of chlorambucil in the Yoshida ascites …


BT Hill - Biochemical pharmacology, 1972 - ncbi.nlm.nih.gov
1: Biochem Pharmacol. 1972 Feb 15;21(4):495-502. Studies on the transport and cellular
distribution of chlorambucil in the Yoshida ascites sarcoma. Hill BT. ...
Cited by 24 - Related articles

[PDF] Isolation and characterization of a Chinese hamster ovary cell line resistant to bifunctional …


CN Robson, J Alexander, AL Harris, ID … - Cancer Res, 1986 - AACR
ABSTRACT A drug-resistant derivative of a Chinese hamster ovary cell line has
been generated by chronic exposure to progressively higher concentra tions of
chlorambucil. The cells exhibit greater than 20-fold resistance to the ...
Cited by 26 - Related articles - All 4 versions

[CITATION] Combination chemotherapy with cyclophosphamide, vincristine, and prednisone in the …


MM Oken, ME Kaplan - Cancer treatment reports, 1979 - ncbi.nlm.nih.gov
1: Cancer Treat Rep. 1979 Mar;63(3):441-7. Combination chemotherapy with
cyclophosphamide, vincristine, and prednisone in the treatment ...
Cited by 36 - Related articles

Phase II trial of recombinant leukocyte A interferon in patients with advanced chronic …


KA Foon, GC Bottino, PG Abrams, MF Fer, … - The American journal of medicine, 1985 - cat.inist.fr
Phase II trial of recombinant leukocyte A interferon in patients with advanced
chronic lymphocytic leukemia. KA FOON, GC BOTTINO, PG ...
Cited by 73 - Related articles - All 4 versions

Transport, metabolism, and DNA interaction of melphalan in lymphocytes from patients with …

- aacrjournals.org [PDF] 
L Panasci, D Henderson, SJ Torres-Garcia, V … - Cancer Research, 1988 - AACR
The nitrogen mustards are an important group of alkylating agents with activity
against several human tumors (1-4). Many of the nitrogen mustard analogues enter
cells by carrier-me diated transport systems and alkylate DNA, RNA, and ...
Cited by 42 - Related articles - All 3 versions


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