M PACKER - Annals of internal medicine, 1985 - Am Coll Physicians Vasodilator drugs were initially administered to patients with primary pulmonary
hypertension based on the unproven hypothesis that pulmonary vasoconstriction
played an important role in the pathogenesis of the disease. There were ... Cited by 99 - Related articles - All 4 versions
RG PEARL, MH ROSENTHAL, JS SCHROEDER … - Annals of Internal Medicine, 1983 - Am Coll Physicians Therapy of pulmonary hypertension is limited by the low potency and adverse
effects of current pulmonary vasodilators. The hemodynamic effects of
nitroglycerin in human pulmonary hypertension are not known. We ... Cited by 50 - Related articles - All 3 versions
M Packer, B Greenberg, B Massie, H Dash - New England Journal of Medicine, 1982 - content.nejm.org Thirteen consecutive patients with primary and secondary pulmonary hypertension
who had normal left ventricular function were treated with hydralazine in an
effort to reduce pulmonary vascular resistance and clinical symptoms. ... Cited by 113 - Related articles - All 3 versions
JT Reeves, BM Groves, D Turkevich - The American review of respiratory disease, 1986 - ncbi.nlm.nih.gov The treatment of primary pulmonary hypertension with pulmonary vasodilator
agents is controversial. Some patients have benefited, while others have not. To
shed light on the mater we reviewed published reports of 117 patients ... Cited by 90 - Related articles - All 3 versions
- ►ahajournals.org [PDF] S Rich, BH Brundage, PS Levy - Circulation, 1985 - Am Heart Assoc ABSTRACT The short- and long-term hemodynamic effects of vasodilators in
patients with primary pulmonary hypertension have been studied, but whether they
affect survivalis unknown. We measured the short-term response to ... Cited by 74 - Related articles - All 5 versions
MD McGoon, RE Vlietstra - Mayo Clinic proceedings. Mayo Clinic, 1984 - ncbi.nlm.nih.gov Primary pulmonary hypertension is an uncommon but serious disease that often
results in debilitating symptoms and early death. One approach to treatment has
been to attempt reduction of pulmonary arterial pressure and right ... Cited by 22 - Related articles - All 2 versions
HI Palevsky, AP Fishman - Annual review of medicine, 1985 - Annual Reviews Primary pulmonary hypertension is a clinical syndrome characterized by pulmonary
hypertension in the absence of sufficient underlying heart or lung disease to
account for it (1-3). In essence, it is "unexplained" pulmonary arterial ... Cited by 13 - Related articles - All 4 versions
LJ Rubin, RH Peter - New England Journal of Medicine, 1980 - content.nejm.org To evaluate the hemodynamic effects of hydralazine in four patients with primary
pulmonary hypertension, we catheterized the right side of the heart before and
48 hours after starting therapy with oral hydralazine, 50 mg every six ... Cited by 132 - Related articles - All 5 versions
- ►ahajournals.org [PDF] LJ Rubin, BM Groves, JT Reeves, M Frosolono … - Circulation, 1982 - Am Heart Assoc SUMMARY To evaluate the effects ofprostacyclin (prostaglandin 12) on pulmonary
vascular tone in primary pulmonary hypertension (PPH), we performed right-heart
catheterization on seven patients with PPH and made hemodynamic ... Cited by 167 - Related articles - All 4 versions
… , D BAMBACH, MJ THOMPSON, P HUSS, … - Annals of Internal Medicine, 1982 - Am Coll Physicians Ten women with primary pulmonary hypertension had resting hemodynamic
measurements taken before and after the nonparenteral administration of various
vasodilators and prostaglandin inhibitors. Only sublingual isoproterenol, ... Cited by 44 - Related articles - All 2 versions