M BARZA - Annals of internal medicine, 1985 - Am Coll Physicians Imipenem, the first of a new class of carbapenem antibiotics, has potent activity against most
clinically important species of bacteria, including isolates resistant to other antibiotics. The drug
is well distributed to most tissues and fluids after intravenous administration; however, ... Cited by 51 - Related articles - All 4 versions
GB Calandra, M Hesney, C Grad - European Journal of Clinical Microbiology & …, 1984 - Springer Imipenem/cilastatin (MK0787/MK0791; N-formimi- doyl thienamcycin/inhibitor) is a broad-spectrum
carbapenem antibiotic with in vitro activity against almost all gram-positive and gram-negative
aerobic and anaerobic bacteria (1,2): In the first comparative clinical trials imipenem/ ... Cited by 19 - Related articles - All 3 versions
RL Yost, JD Lee, JP O'Leary - The American surgeon, 1977 - ncbi.nlm.nih.gov Our patient was severely injured, and had a prolonged period of hypotension. After operation
she received moderate doses of cefazolin, intravenously, in the face of acute renal failure. Seizures
associated with a serum cefazolin level of 455 mg/ml were observed. Although a cause ... Cited by 20 - Related articles
- ►nih.gov [PDF] S Hori, S Kurioka, M Matsuda, J Shimada - Antimicrobial agents and …, 1985 - Am Soc Microbiol ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Apr. 1985, p. 650-651 ... Inhibitory Effect
of Cephalosporins on y-Aminobutyric Acid ... SEIJI HORI,l* SUSUMU KURIOKA,1 MAKOTO
MATSUDA,1 ... Department of Biochemistry' and Second Department ofInternal ... Cited by 28 - Related articles - All 7 versions
GG Jackson - Reviews of Infectious Diseases, 1983 - jstor.org Three generations of aminoglycoside antibiotics have been produced for the purpose (and with
the net effect) of decreasing the prevalence of resistant bacterial strains and diminishing the
toxic effects of the drugs on the host. A considerable measure of success in the former ... Cited by 8 - Related articles
RB Sykes, DP Bonner - The American Journal of Medicine, 1985 - Elsevier A novel screening procedure led to isolation of the structurally unique, bacterially produced,
monocyclic beta-lactam antibiotics early in 1979. These naturally occurring “monobactams” were
not clinically useful as antibiotics because of their poor antibacterial properties. They ... Cited by 32 - Related articles - All 2 versions
RA Salata, RL Gebhart, DL Palmer, BH Wade, … - The American journal of …, 1985 - ncbi.nlm.nih.gov In an open, prospective, multicenter trial the efficacy and tolerance of imipenem/cilastatin for
the treatment of bacterial pneumonia was investigated. Forty-three adults were studied: 29 with
nosocomial and 14 with community-acquired infections. Significant underlying disease ... Cited by 36 - Related articles
FP Tally, CE Sullivan - Pharmacotherapy - ncbi.nlm.nih.gov Metronidazole is a 5-nitroimidazole that has selective activity against anaerobic
microorganisms, including bacteria and protozoa. Intravenous metronidazole has recently been
approved by the US Food and Drug Administration for the treatment of serious anaerobic ... Cited by 15 - Related articles
JG Bartlett - Medical Clinics of North America, 1982 - csa.com Chloramphenicol. JG Bartlett Medical Clinics of North America 66:11, 91-102, 1982.
Chloramphenicol is produced by an actinomycete, Streptomyces venezuelae , which
was initially found in soil sample in Venezuela in 1947. ... Cited by 15 - Related articles - All 3 versions