AM LEVINE, PS GILL, J COHEN, JG … - Annals of internal …, 1986 - Am Coll Physicians The human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) requires
reverse transcriptase for viral replication. We treated 12 patients who had acquired immunodeficiency
syndrome and active HTLV-III/LAV viremia with suramin, a potent competitive inhibitor of ... Cited by 70 - Related articles - All 3 versions
BD Cheson, AM Levine, D Mildvan, LD Kaplan, P Wolfe … - Jama, 1987 - Am Med Assoc Suramin sodium is a reverse transcriptase inhibitor with in vitro activity against the human immunodeficiency
virus (HIV), the causative agent of acquired immunodeficiency syndrome (AIDS). Ninety-eight
patients with AIDS manifest as opportunistic infections (n = 38), AIDS with Kaposi's ... Cited by 57 - Related articles - All 4 versions
E De Clercq - Cancer letters, 1979 - ncbi.nlm.nih.gov Suramin--a well-known antitrypanosomal agent--was found to exert a strong inhibitory effect
on the RNA-directed DNA polymerase (reverse transcriptase) activity of several oncornaviruses
such as Moloney murine leukemia virus, murine Rauscher leukemia viruses, Moloney ... Cited by 151 - Related articles
S Broder, JM Collins, PD Markham, RR Redfield… - The Lancet, 1985 - Elsevier Suramin was given to ten outpatients with acquired immunodeficiency syndrome (AIDS) presenting
as Kaposi's sarcoma (KS) or as an AIDS-related complex (ARC). Side-effects associated with
the administration of 6·2 g of suramin over 5 weeks included fevers, rashes, urinary ... Cited by 106 - Related articles - All 6 versions
LD Kaplan, PR Wolfe, PA Volberding, P … - American Journal of …, 1987 - grande.nal.usda.gov Record Detail. Return to previous page, Save: Title: Lack of response to suramin
in patients with AIDS and AIDS-related complex. Author: Kaplan, LD : Wolfe, PR :
Volberding, PA : Feorino, P : Levy, JA : Abrams, DI : Kiprov, D ... Cited by 24 - Related articles - Cached - All 4 versions
H Mitsuya, M Popovic, R Yarchoan, S Matsushita, RC … - Science, 1984 - sciencemag.org Approximately 3 years ago, an appar- ently new and unexplained disorder called acquired immune
deficiency syn- drome (AIDS) was recognized (1-3). The disorder is a pandemic
immunosuppres- sive disease that predisposes to life- threatening infections with ... Cited by 241 - Related articles - All 7 versions
F Hawking - Adv Pharmacol Chemother, 1978 - books.google.com Suramin: With Special Reference to Onchocerciasis F. HAWKING The Commonwealth Institute
of Helminthology St. Albans, England I. Introduction 289 II. Chemistry 290 A. Physical Characteristics
290 B. Methods of Estimation 291 C. Relation of Structure and Activity 291 III. Absorption ... Cited by 182 - Related articles - All 3 versions
JM Collins, RW Klecker… - The Journal of Clinical …, 1986 - jclinpharm.highwire.org On behalf of: American College of Clinical Pharmacology ... Jerry M. Collins PhD, Raymond
W. Klecker, Jr, MD, Robert Yarchoan, MD, ... H. Clifford Lane, MD, Anthony S. Fauci, MD, Robert
R. Redfield, MD, ... Samuel Broder, MD, and Charles E. Myers, MD Cited by 71 - Related articles - All 5 versions
P Feuillan, M Raffeld, CA Stein, N Lipford, D … - Journal of Clinical …, 1987 - Endocrine Soc There have been reports of adrenal failure in patients treated with suramin, an agent that has
recently been used as therapy for acquired immune deficiency syndrome. We conducted this
study to assess the effect of suramin on adrenal function and structure in a primate, the ... Cited by 21 - Related articles - All 5 versions
- ►ascopubs.org [PDF] CA Stein, RV LaRocca, R Thomas, N McAtee, … - Journal of Clinical …, 1989 - jco.ascopubs.org From the Medicine Branch, Clinical Oncology Program, National Cancer Institute, National Institutes
of Health, Bethesda, MD. Submitted August 9, 1988; accepted November 21, 1988. Address
reprint requests to Charles E. Myers, MD, Medi- cine Branch, Clinical Oncology Program, ... Cited by 250 - Related articles - All 5 versions
