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Scholar Results 1 - 10 of about 101 related to ABERNETHY: Verapamil pharmacodynamics and disposition in young and elderly hypertensive patients:.... (0.15 sec) 

Verapamil pharmacodynamics and disposition in young and elderly hypertensive patients: …


DR ABERNETHY, JB SCHWARTZ, EL TODD, … - Annals of internal medicine, 1986 - Am Coll Physicians
We studied verapamil pharmacodynamics and disposition in seven young, ten
elderly, and seven very elderly hypertensive males. Maximal decrease in mean (±
SD) blood pressure tended to be greater in the elderly (-13.5 ± 5.9 mm Hg) ...
Cited by 75 - Related articles - All 3 versions

Responses to intravenous and oral diltiazem in elderly and younger patients with systemic …


JB Schwartz, DR Abernethy - The American journal of cardiology, 1987 - ncbi.nlm.nih.gov
1: Am J Cardiol. 1987 May 1;59(12):1111-7. Responses to intravenous and oral diltiazem
in elderly and younger patients with systemic hypertension. ...
Cited by 37 - Related articles - All 2 versions

Stereoselective verapamil disposition and dynamics in aging during racemic verapamil …


DR Abernethy, IW Wainer, JA Longstreth, NS … - Journal of Pharmacology and Experimental …, 1993 - ASPET
Page 1. Vol. 266, No.2 Printed in USA ABSTRACT 0022.3565/93/2662.0904$03.OO/
O THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS ...
Cited by 34 - Related articles - BL Direct - All 3 versions

Aging alters verapamil elimination and dynamics: single dose and steady-state responses


JB Schwartz - Journal of Pharmacology and Experimental …, 1990 - ASPET
Page 1. Vol. 255, No. 1 Printed in USA ABSTRACT ABBREVIATIONS: AV, atnoventncular;
PA, time from onset of P wave to onset of A wave on the surface ...
Cited by 27 - Related articles - All 3 versions

Effects of amlodipine, a long-acting dihydropyridine calcium antagonist in aging …


DR Abernethy, J Gutkowska, LM Winterbottom - Clinical Pharmacology & Therapeutics, 1990 - nature.com
Pharmacodynamics and disposition of amlodipine, a dihydropyridine calcium
antagonist, were compared between elderly and young patients with hypertension.
Elderly (mean SD; age, 68 3 years) and young (35 5 years) patients received ...
Cited by 67 - Related articles - All 3 versions

Aging effects on stereoselective pharmacokinetics and pharmacodynamics of verapamil


JB Schwartz, IF Troconiz, D Verotta, S Liu, H … - Journal of Pharmacology and Experimental …, 1993 - ASPET
Departments of Medicine (JBS) and Pharmacy (JBS, SL, HC), Laboratory Medicine
(IFT, DV.), Anesthesia (DV.) and the Cardiovascular ... Research Institute
(JBS), University of California, San Francisco, California
Cited by 26 - Related articles - BL Direct - All 3 versions

Calcium antagonists in the elderly. A risk-benefit analysis.


JB Schwartz - Drugs & aging, 1996 - ncbi.nlm.nih.gov
Calcium antagonists are effective in lowering blood pressure, relieving anginal
symptoms and improving exercise tolerance in older and younger patients with
coronary artery disease. Verapamil and diltiazem are effective in slowing ...
Cited by 23 - Related articles - BL Direct - All 2 versions

Age-related changes in the pharmacokinetics and pharmacodynamics of nifedipine.

- nih.gov [PDF] 
DR Robertson, DG Waller, AG Renwick, CF … - British journal of clinical pharmacology, 1988 - pubmedcentral.nih.gov
1 Theeffects of age on the pharmacology ofnifedipine were investigated in 11
young and six elderly normotensive volunteers. 2 Following 2.5 mg of nifedipine
iv the plasma clearance of nifedipine was 348 ą 83 (sd) ml min-1 in the ...
Cited by 71 - Related articles - All 5 versions

Aging of women alters S-verapamil pharmacokinetics and pharmacodynamics


JB Schwartz, H Capili, J Daugherty - Clinical Pharmacology & Therapeutics, 1994 - nature.com
Pharmacokinetics and pharmacodynamics of S-verapamil were studied in 25 healthy
nonsmoking women ranging in age from 23 to 33 years (young) and from 63 to 79
years (elderly) after 15-minute intravenous infusions of 0.10 to 0.11 ...
Cited by 42 - Related articles - BL Direct - All 3 versions

Verapamil pharmacodynamics and disposition in obese hypertensive patients


DR Abernethy, JB Schwartz - Journal of cardiovascular pharmacology, 1988 - journals.lww.com
210 DR ABERNETHY AND JB SCHWARTZ Unfortunately, little is known about alteration
in drug effect in obese hypertensive patients; how- ever, for cardiovascularly
active drugs such as ve- rapamil, alteration in pharmacodynamics may occur ...
Cited by 20 - Related articles - All 4 versions


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