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Scholar Results 1 - 10 of about 101 related to KURZROCK: Rearrangement in the breakpoint cluster region and the clinical course in Philadelphia-.... (0.10 sec) 

Rearrangement in the breakpoint cluster region and the clinical course in …


R KURZROCK, MB BLICK, M TALPAZ, WS … - Annals of internal …, 1986 - Am Coll Physicians
We have followed one patient with Philadelphia (Ph)-negative chronic myelogenous leukemia
and identified an additional four patients from the literature who showed the rearrangement in
the breakpoint cluster region (bcr) on chromosome 22 characteristic of Ph-positive ...
Cited by 50 - Related articles - All 3 versions

Do oncogenes determine clinical features in chronic myeloid leukaemia?


O Dreazen, F Rassool, RS Sparkes, I Klisak, JM … - The Lancet, 1987 - Elsevier
Oncogene abnormalities are thought to have a central role in some human malignant
disorders, particularly Burkitt leukaemia/ lymphoma and chronic myeloid leukaemia (CML).
However, the extent to which specific oncogene changes determine the clinical features ...
Cited by 39 - Related articles - All 4 versions

Rearrangement of the bcr gene in Philadelphia chromosome-negative chronic …

- hematologylibrary.org [PDF] 
TS Ganesan, F Rassool, AP Guo, KH Th'ng, … - …, 1986 - bloodjournal.hematologylibrary.org
. Hematology; all rights reserved Copyright 2007 by The American Society of DC 20036. by the
American Society of Hematology, 1900 M St, NW, Suite 200, Washington Blood (print ISSN
0006-4971, online ISSN 1528-0020), is published semimonthly ... For personal use only. ...
Cited by 67 - Related articles - All 6 versions

Genomic diversity correlates with clinical variation in Ph′-negative chronic …


CM Morris, AE Reeve, PH Fitzgerald, PE Hollings, MEJ … - 1986 - nature.com
The Philadelphia chromosome (Ph') is found in the blood cells of about 90% of patients with
chronic myeloid leukaemia (CML) and usually results from the reciprocal chromosome translocation
t(9; 22) 1,2 . This translocation relocates the proto-oncogene c-abl, normally found on ...
Cited by 90 - Related articles - All 4 versions

C-abl and bcr are rearranged in a Ph1-negative CML patient.

- nih.gov [PDF] 
CR Bartram, E Kleihauer, A De Klein, G … - The EMBO …, 1985 - pubmedcentral.nih.gov
Department of Pediatrics II, University of Ulm, D-7900, FRG, 1Department of Cell Biology and
Genetics, Erasmus University, 3000 DR Rotterdam, The Netherlands,
2Histology-Embryology-Cytogenetics Laboratory, University Hospital, F-51092 Reims, ...
Cited by 113 - Related articles - All 4 versions

Philadelphia-negative chronic myelogenous leukemia with breakpoint cluster …

- ascopubs.org [PDF] 
M Shtalrid, M Talpaz, M Blick, P Romero, H … - Journal of Clinical …, 1988 - jco.ascopubs.org
PATIENTS with Philadelphia (Ph)-positive chronic myelogenous leukemia (CML) have characteristic
clinical and morphological fea- tures: splenomegaly, a hypercellular bone mar- row with granulocytic
hyperplasia, impressive neutrophilia, basophilia, frequent thrombocyto- sis, and a low ...
Cited by 35 - Related articles - All 5 versions

Identification of molecular variants of p210bcr-abl in chronic myelogenous …

- bloodjournal.org [PDF] 
R Kurzrock, WS Kloetzer, M Talpaz, M Blick, R Walters, … - Blood, 1987 - Am Soc Hematology
. Hematology; all rights reserved Copyright 2007 by The American Society of DC 20036. by the
American Society of Hematology, 1900 M St, NW, Suite 200, Washington Blood (print ISSN
0006-4971, online ISSN 1528-0020), is published semimonthly ... For personal use only. ...
Cited by 44 - Related articles - All 4 versions

Philadelphia chromosome-negative chronic myelogenous leukemia without …

- hematologylibrary.org [PDF] 
R Kurzrock, HM Kantarjian, M Shtalrid, JU … - …, 1990 - bloodjournal.hematologylibrary.org
HE KARYOTYPIC hallmark of chronic myelogenous T leukemia (CML) is a shortened chromosome
22, desig- ... From the Department of Clinical Immunology and Biological Therapy and the Department
of Hematology, The University of Texas, MD Anderson Cancer Center, Houston, TX. ...
Cited by 80 - Related articles - All 4 versions

Ph 1 -negative chronic granulocytic leukemia: a nonentity


LB Travis, RV Pierre, GW DeWald - American journal of clinical pathology, 1986 - cat.inist.fr
Ph 1 -negative chronic granulocytic leukemia: a nonentity. LB TRAVIS, RV PIERRE,
GW DEWALD American journal of clinical pathology 85:22, 186-193, American Society
of Clinical Pathologists, 1986. L'étude porte sur 24 ...
Cited by 58 - Related articles - All 3 versions

What is the contribution of molecular studies to the diagnosis of BCR-ABL-positive …


H Kantarjian, M Talpaz, E Estey, S Ku, R Kurzrock - The American journal of …, 1994 - Elsevier
The detection of BCR-ABL transcripts by polymerase chain reaction and hybridization protection
assay was investigated in 59 adults with acute leukemia in whom the Philadelphia chromosome
(Ph) abnormality was not documented by cytogenetic analysis. These included 35 ...
Cited by 13 - Related articles - BL Direct - All 4 versions


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