CE Cross, B HALLIWELL, ET BORISH, WA … - Annals of internal …, 1987 - Am Coll Physicians Toxic oxygen free radicals have been implicated as important pathologic mediators in many
clinical disorders. We discuss the chemistry of oxygen radical production and the roles of iron
and of various antioxidants as well as the diseases that have received active attention in ... Cited by 965 - Related articles - All 4 versions
BA Freeman, JD Crapo - Laboratory investigation; a journal of technical …, 1982 - ncbi.nlm.nih.gov A free radical is any molecule that has an odd number of electrons. Free radicals, which can
occur in both organic (ie, quinones) and inorganic molecules (ie, O(2)), are highly reactive
and, therefore, transient. Free radicals are generated in vivo as by products of normal ... Cited by 1715 - Related articles - All 2 versions
- ►nih.gov [PDF] MS Paller, JR Hoidal, TF Ferris - Journal of Clinical Investigation, 1984 - pubmedcentral.nih.gov Abst ract. During renal ischemia, ATP is de- graded to hypoxanthine. When xanthine oxidase
converts hypoxanthine to xanthine in the presence of molecular oxygen, superoxide radical
(O°) is generated. We studied the role ofO° and its reduction product OH * in mediating ... Cited by 602 - Related articles - All 6 versions
JM McCord - New England Journal of Medicine, 1985 - content.nejm.org It is now clear that oxygen-derived free radicals play an important part in several models of experimentally
induced reperfusion injury. Although there are certainly multiple components to clinical ischemic
and reperfusion injury, it appears likely that free-radical production may make a major ... Cited by 3813 - Related articles - All 4 versions
DA Parks, GB Bulkley, DN Granger - Surgery, 1983 - ncbi.nlm.nih.gov Evidence is presented that supports a role of oxygen free radicals in the pathogenesis of various
disorders of the digestive system. In the intestine, there is evidence that oxygen radicals play
an important role in the endothelial and epithelial damage associated with certain models ... Cited by 274 - Related articles - All 2 versions
PA Southorn, G Powis - Mayo Clin Proc, 1988 - grande.nal.usda.gov Record Detail. Return to previous page, Save: Title: Free radicals in medicine. I.
Chemical nature and biologic reactions. Author: Southorn, PA : Powis, G Citation:
Mayo-Clin-Proc. 1988 Apr; 63(4): 381-9 Abstract: Free radicals ... Cited by 313 - Related articles - Cached - All 3 versions
B Halliwell, JMC Gutteridge, CE Cross - The Journal of laboratory and clinical …, 1992 - cat.inist.fr Free radicals, antioxidants, and human disease: where are we now? B HALLIWELL,
JMC GUTTERIDGE, CE CROSS The Journal of laboratory and clinical medicine
119:66, 598-620, Elsevier, 1992. Homme; Human; Hombre ... Cited by 2218 - Related articles - BL Direct - All 9 versions
L Baud, R Ardaillou - American Journal of Physiology- Renal …, 1986 - Am Physiological Soc BAUD, LAURENT, AND RAYMOND ARDAILLOU. Reactive oxygen species: production and
role in the kidney. Am. J. Physiol. 251 (Renal Fluid Elec- trolyte Physiol. 20):
F765-F776,1986.-Reactive oxygen species (ROS) are formed by incomplete reduction of ... Cited by 190 - Related articles - All 3 versions
- ►ahajournals.org [PDF] R Bolli, WX Zhu, CJ Hartley, LH Michael, JE Repine, … - Circulation, 1987 - Am Heart Assoc ROBERTO BOLLI, MD, WEI-XI ZHU, MD, CRAIG J. HARTLEY, PH.D., LLOYD H. MICHAEL,
PH.D., ... JOHN E. REPINE, MD, MICHAEL L. HESS, MD, RAKESH C. KUKREJA, PH.D., ... ABSTRACT
The mechanism for the prolonged contractile dysfunction observed in myocardium Cited by 145 - Related articles - All 4 versions