PW STACPOOLE, AC LORENZ, RG THOMAS … - Annals of internal medicine, 1988 - Am Coll Physicians An open, prospective evaluation of the effects of dichloroacetate on morbidity
and survival time was done in 29 pediatric and adult patients with lactic
acidosis. Dichloroacetate was administered intravenously over 30 minutes as ... Cited by 77 - Related articles - All 5 versions
- ►nih.gov [PDF] R Park, AI Arieff, W Leach, VC Lazarowitz - Journal of Clinical Investigation, 1982 - pubmedcentral.nih.gov ABSTRACT Lactic acidosis is a clinical condition due to accumulation of H+ ions
from lactic acid, char- acterized by blood lactate levels >5 mM and arterial pH
<7.25. In addition to supportive care, treatment usually consists of ... Cited by 47 - Related articles - All 4 versions
PW Stacpoole, EM Harman, SH Curry, TG … - New England Journal of Medicine, 1983 - content.nejm.org We administered dichloroacetate, which prevents or reverses hyperlactatemia in
animals and lowers plasma lactate levels in human beings, to 13 patients with
lactic acidosis of various causes. All had hypotension, and their acidemia ... Cited by 122 - Related articles - All 2 versions
- ►ahajournals.org [PDF] RM Bersin, AI Arieff - Circulation, 1988 - Am Heart Assoc ABSTRACT Carbicarb is a mixture of Na2CO3/NaHCO3 that buffers similarly ...
N2). Dogs with HLA (n = 28) were then treated with 2.5 meq/kg of either NaHCO3
or carbicarb over ... 1 hr. Measurements were made, after 1 hr of hypoxia ... Cited by 84 - Related articles - All 4 versions
PW Stacpoole, EC Wright, TG Baumgartner, … - New England Journal of Medicine, 1992 - content.nejm.org BACKGROUND. Mortality is very high in lactic acidosis, and there is no
satisfactory treatment other than treatment of the underlying cause.
Uncontrolled studies have suggested that dichloroacetate, which stimulates ... Cited by 137 - Related articles - BL Direct - All 4 versions
JH Sun, GF Filley, K Hord, NB Kindig, EJ … - Surgery, 1987 - grande.nal.usda.gov Record Detail. Return to previous page, Save: Title: Carbicarb: an effective
substitute for NaHCO3 for the treatment of acidosis. ... Cited by 36 - Related articles - Cached - All 3 versions
A Yatani, T Fujino, K Kinoshita, M Goto - Journal of molecular and cellular cardiology, 1981 - ncbi.nlm.nih.gov 1: J Mol Cell Cardiol. 1981 Feb;13(2):147-61. Excess lactate modulates ionic
currents and tension components in frog atrial muscle. ... Cited by 31 - Related articles
DJ Cooper, KR Walley, BR Wiggs, JA Russell - Annals of Internal Medicine, 1990 - Am Coll Physicians Add to CiteULike Add to Complore Add to Connotea Add to Del.icio.us Add to Digg
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Study Objective: To determine whether correction of acidemia using ... Cited by 203 - Related articles - All 4 versions
