JS WOLFSON, DC HOOPER - Annals of internal medicine, 1988 - Am Coll Physicians Norfloxacin is an oral fluoroquinolone antimicrobial agent recently released for
the treatment of uncomplicated and complicated urinary tract infections. The
drug antagonizes DNA gyrase, an enzyme essential for bacterial DNA ... Cited by 48 - Related articles - All 4 versions
R Wise - J Antimicrob Chemother, 1984 - Br Soc Antimicrob Chemo A review of the pharmacokinetics of the highly active quinoline derivative,
norfloxacin, is presented. The compound appears to be rapidly absorbed. The
serum half-life is about 3-5 h and 30% of a given dose is recovered in the ... Cited by 34 - Related articles - All 3 versions
C Cherubin, S Stilwell - Scandinavian journal of infectious diseases. …, 1986 - ncbi.nlm.nih.gov As part of a multicenter randomized trial of the treatment of complicated
urinary infections in hospitalized patients, we treated 35 patients of whom 28
were evaluable (16 patients given parenteral therapy and 12 norfloxacin). ... Cited by 13 - Related articles - All 2 versions
CE Cox, RE McCabe, C Grad - The American journal of medicine, 1987 - ncbi.nlm.nih.gov In a multiclinic, randomized trial, oral norfloxacin, a fluoroquinolone
antibacterial, was compared with several standard parenteral regimens for the
treatment of nonbacteremic, hospital-acquired urinary tract infections. ... Cited by 15 - Related articles
A Lublin, S Mechani, M Malkinson, Y … - Avian Diseases, 1993 - jstor.org SUMMARY. The efficacy of the antimicrobial drug norfloxacin for treating
infectious coryza was examined in 26-week-old male broiler breeders. Chickens
were inoculated in the infra- orbital sinus with the causal organism, ... Cited by 5 - Related articles - BL Direct - All 3 versions
ML Corrado, C Grad, J Sabbaj - The American journal of medicine, 1987 - ncbi.nlm.nih.gov A retrospective analysis of data from the treatment of 95 men with nonbacteremic
urinary tract infections (UTIs) (clean-catch urinary bacterial count greater
than or equal to 10(5) colony-forming units/ml) who received norfloxacin ... Cited by 8 - Related articles
HG De Vries-Hospers, GW Welling, D Van der … - Progress in clinical and biological research, 1985 - ncbi.nlm.nih.gov During five consecutive days three different dosages of 200, 400 and 800 mg
norfloxacin were administered to ten healthy males. Cultures of feces and oral
washings revealed that even the lowest dose was effective in eliminating ... Cited by 10 - Related articles
C Edlund, T Bergan, K Josefsson, R Solberg, … - Scandinavian Journal of Infectious Diseases, 1987 - Informa Pharma Science INTRODUCTION Norfloxacin has a wide antibacterial spectrum directed primarily
against enterobacteria, branhamella, gonococci and haemophilus (1-3). Its
therapeutic effect is particularly good in urinary tract infections, ... Cited by 26 - Related articles - All 6 versions
EM Brown, R Morris, TP Stephenson - The Journal of antimicrobial chemotherapy, 1986 - ncbi.nlm.nih.gov The efficacy of ciprofloxacin in the treatment of chronic Pseudomonas aeruginosa
urinary tract infection was assessed in 16 patients with functional or
anatomical abnormalities of the urinary tract. Depending on renal function ... Cited by 13 - Related articles
- ►nih.gov [PDF] TD Gootz - Clinical Microbiology Reviews, 1990 - Am Soc Microbiol 0893-8512/90/010013-19$02.00/0 Copyright C) 1990, American Society for
Microbiology ... Discovery and Development of New Antimicrobial Agents ...
THOMAS D. GOOTZ Pfizer Central Research, Groton, Connecticut 06340 Cited by 30 - Related articles - All 6 versions