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Scholar Results 1 - 10 of about 101 related to O'DWYER: 2'-Deoxycoformycin (Pentostatin) for lymphoid malignancies: Rational development.... (0.09 sec) 

2'-Deoxycoformycin (Pentostatin) for lymphoid malignancies: Rational development of an …


PJ O'DWYER, B WAGNER, B LEYLAND- … - Annals of Internal Medicine, 1988 - Am Coll Physicians
A new antimetabolite, 2'-deoxycoformycin (pentostatin), has striking antitumor
activity in several lymphoid neoplasms. Isolated from cultured soil organisms,
this purine analogue is a potent inhibitor of adenosine deaminase (ADA), ...
Cited by 75 - Related articles - All 2 versions

Low-dose deoxycoformycin in lymphoid malignancy

- ascopubs.org [PDF] 
MR Grever, JM Leiby, EH Kraut, HE Wilson, JA … - Journal of Clinical Oncology, 1985 - jco.ascopubs.org
Deoxycoformycin (dCF), a potent inhibitor of adeno- sine deaminase (ADA), was
explored for its antineo- plastic potential in 28 patients with advanced
lymphoid malignancy. Both normal and malignant B lymphocytes have low ...
Cited by 113 - Related articles - All 5 versions

Pentostatin in chronic lymphocytic leukemia: A phase II trial of Cancer and Leukemia Group …

- jcojournal.org [PDF] 
RO Dillman, R Mick, OR McIntyre - Journal of Clinical Oncology, 1989 - jcojournal.org
From the University of California San Diego School of Medicine, La Jolla;
Harvard School of Public Health, Boston; and Norris Cotton Cancer Center,
Hanover, NH. Submitted August 1, 1988; accepted November 16, 1988. This ...
Cited by 106 - Related articles - All 6 versions

Response to pentostatin in hairy-cell leukemia refractory to interferon-alpha. The …

- jcojournal.org [PDF] 
AD Ho, J Thaler, F Mandelli, F Lauria, R … - Journal of Clinical Oncology, 1989 - jcojournal.org
DURING the last 6 years, clinical trials in hairy-cell leukemia (HCL) have shown
dramatic activity for interferon-alfa (IFN-a) and 2'-deoxycoformycin
(pentostatin; DCF).14 Summarizing the results from several multi- center ...
Cited by 45 - Related articles - All 5 versions

Deoxycoformycin in the treatment of mature B-cell malignancies.


C Dearden, D Catovsky - British Journal of Cancer, 1990 - pubmedcentral.nih.gov
Full text is available as a scanned copy of the original print version. Get a
printable copy (PDF file) of the complete article (430K), or click on a page
image below to browse page by page. Links to PubMed are also available for ...
Cited by 31 - Related articles - All 2 versions

Pentostatin in refractory chronic lymphocytic leukemia: a phase II trial of the European …

- oxfordjournals.org [PDF] 
AD Ho, J Thaler, P Stryckmans, B Coiffier, M … - JNCI Journal of the National Cancer Institute, 1990 - jnci.oxfordjournals.org
Pentostatin was used to treat 26 patients with advanced B-cell chronic lympho-
cytic leukemia resistant to conventional treatment. Twenty patients had pro-
gressive disease on previous regimens and six had had partial remission and ...
Cited by 60 - Related articles - All 5 versions

The biochemical and clinical consequences of 2'-deoxycoformycin in refractory …

- hematologylibrary.org [PDF] 
MR Grever, MF Siaw, WF Jacob, JA Neidhart, … - Blood, 1981 - bloodjournal.hematologylibrary.org
. Hematology; all rights reserved Copyright 2007 by The American Society of DC
20036. by the American Society of Hematology, 1900 M St, NW, Suite 200,
Washington Blood (print ISSN 0006-4971, online ISSN 1528-0020), is ...
Cited by 141 - Related articles - All 4 versions

Phase II trial of pentostatin in refractory lymphomas and cutaneous T-cell disease

- ascopubs.org [PDF] 
FJ Cummings, K Kim, RS Neiman, RL Comis, … - Journal of Clinical Oncology, 1991 - jco.ascopubs.org
Thirty-seven patients with refractory lymphoma or cutaneous T-cell lymphoma were
treated with 2'- deoxycoformycin (pentostatin; dCF), 5 mg/m2 intrave- nous (IV)
bolus for 3 consecutive days of every 3-week cycle in this Eastern ...
Cited by 63 - Related articles - All 7 versions

An investigation of 2'-deoxycoformycin in the treatment of cutaneous T-cell lymphoma

- hematologylibrary.org [PDF] 
MR Grever, E Bisaccia, DA Scarborough, EN … - Blood, 1983 - bloodjournal.hematologylibrary.org
. Hematology; all rights reserved Copyright 2007 by The American Society of DC
20036. by the American Society of Hematology, 1900 M St, NW, Suite 200,
Washington Blood (print ISSN 0006-4971, online ISSN 1528-0020), is ...
Cited by 74 - Related articles - All 4 versions

Clinical response to deoxycoformycin in chronic lymphoid neoplasms and biochemical changes …

- bloodjournal.org [PDF] 
AD Ho, K Ganeshaguru, WU Knauf, G Dietz, I … - Blood, 1988 - Am Soc Hematology
. Hematology; all rights reserved Copyright 2007 by The American Society of DC
20036. by the American Society of Hematology, 1900 M St, NW, Suite 200,
Washington Blood (print ISSN 0006-4971, online ISSN 1528-0020), is ...
Cited by 18 - Related articles - All 5 versions


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