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Scholar Results 1 - 10 of about 101 related to Rosenberg: New approaches to the immunotherapy of cancer using interleukin-2. (0.08 sec) 

New approaches to the immunotherapy of cancer using interleukin-2


SA Rosenberg, MT LOTZE, JJ MULE - Annals of internal medicine, 1988 - Am Coll Physicians
Experimental studies in animals have shown that therapy with high-dose
interleukin-2 either alone or in combination with lymphokine-activated killer
cells can reduce established pulmonary and hepatic metastases. Based on ...
Cited by 151 - Related articles - All 3 versions

A pilot study of intralymphatic interleukin-2. II. Clinical and biological effects


G Sarna, J Collins, R Figlin, P Robertson, B … - Journal of Immunotherapy, 1990 - journals.lww.com
Summary: Interleukin-2 (recombinant methionyl human interleukin-2 alanine 125;
IL-2) was administered intralymphatically to 12 patients with advanced cancer in
a phase I trial. Doses were administered once a week for 6 weeks in a ...
Cited by 18 - Related articles - All 2 versions

Intratumoral echo-guided injection of interleukin-2 and lymphokine-activated killer cells in …


L Gandolfi, L Solmi, GC Pizza, F Bertoni, R … - Hepato-gastroenterology, 1989 - cat.inist.fr
Intratumoral echo-guided injection of interleukin-2 and lymphokine-activated
killer cells in hepatocellular carcinoma. L GANDOLFI ...
Cited by 21 - Related articles - All 3 versions

Intra-lymphatic administration of interleukin-2 (IL-2) in cancer patients: a pilot study.


G Pizza, D Viza, C De Vinci, PJM Vich, L … - Lymphokine research, 1988 - ncbi.nlm.nih.gov
Seven patients suffering from advanced metastatic tumours, unresponsive to
standard therapies, were treated with 3 to 5 intra-lymphatic injections of
interleukin-2 (IL-2) and IL-2-activated-peripheral blood lymphocytes (PBL). ...
Cited by 16 - Related articles - All 2 versions

Hematopoietic growth factors: biology and clinical application.


JL Gabrilove, A Jakubowski - Journal of the National Cancer Institute. Monographs, 1990 - ncbi.nlm.nih.gov
A number of recently identified cytokines have been implicated in the
development of blood cells and their functional activation. These include
granulocyte colony-stimulating factor (G-CSF), granulocyte/macrophage ...
Cited by 23 - Related articles

High-dose recombinant interleukin 2 in the treatment of patients with disseminated cancer. …


MT Lotze, AE Chang, CA Seipp, C Simpson, … - Jama, 1986 - Am Med Assoc
Experience with the administration of high doses of interleukin 2 (IL-2) alone
is described herein. Ten patients with a variety of malignant disorders
unresponsive to conventional treatments were treated with at least 30,000 ...
Cited by 305 - Related articles - All 3 versions

Lymphokines and cytokines as cancer treatment: immunotherapy realized


EC Borden, PM Sondel, T Biosciences, H … - CA A Cancer Journal for Clinicians - interscience.wiley.com
Human proteins with identified effects on host responses to malignant cells have
been established as effective therapeutic techniques in cancer. Lymphokines,
products of activated cells of the immune system, have pleiotropic ...
Cited by 80 - Related articles - All 2 versions

[CITATION] Cytokines: structure, function and synthesis.


A Kelso - Current opinion in immunology, 1989 - ncbi.nlm.nih.gov
1: Curr Opin Immunol. 1989 Dec;2(2):215-25. Cytokines: structure, function
and synthesis. Kelso A. Walter and Eliza Hall Institute ...
Cited by 63 - Related articles

Local administration of cells containing an inserted IL-2 gene and producing IL-2 inhibits …


J Bubenik, NN Voitenok, J Kieler, VS … - Immunology letters, 1988 - ncbi.nlm.nih.gov
We have prepared a retroviral expression construct, pPS-IL-2, in which human
IL-2 cDNA has been inserted into the polylinker region, and have used the
retroviral vector to introduce the functional IL-2 gene into a fibroblast ...
Cited by 55 - Related articles

Metastatic renal cancer treated with interleukin-2 and lymphokine-activated killer cells: A phase …


RI FISHER, CA COLTMAN Jr, JH DOROSHOW … - Annals of internal medicine, 1988 - Am Coll Physicians
RICHARD I. FISHER, MD; CHARLES A. COLTMAN, Jr., MD; JAMES H. DOROSHOW, MD;
ANTHONY A. RAYNER, MD; MICHAEL J. HAWKINS, MD; JAMES W. MIER, MD; PETER WIERNIK,
MD; JOHN D. MCMANNIS, Ph.D.; GEOFFREY R. WEISS, MD; KIM A. MARGOLIN, MD; ...
Cited by 265 - Related articles - All 4 versions


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