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Scholar Results 1 - 10 of about 101 related to Lehrer: Neutrophils and host defense. (0.12 sec) 

Neutrophils and host defense


RI Lehrer, T Ganz, ME Selsted, BM Babior, JT … - Annals of internal medicine, 1988 - Am Coll Physicians
Neutrophils, the predominant phagocytes of circulating blood, are the first
cells to arrive at sites of infection. Although neutropenia has long been
recognized to predispose to infection, recently other syndromes marked by ...
Cited by 243 - Related articles - All 3 versions

Current concepts: immunology; neutrophils in human diseases


HL Malech, JI Gallin - The New England journal of medicine, 1987 - cat.inist.fr
Current concepts: immunology; neutrophils in human diseases. HL MALECH,
JI GALLIN The New England journal of medicine 317:1111, 687 ...
Cited by 606 - Related articles - All 3 versions

Tissue injury in inflammation. Oxidants, proteinases, and cationic proteins.

- nih.gov [PDF] 
PM Henson, RB Johnston Jr - Journal of Clinical Investigation, 1987 - pubmedcentral.nih.gov
In circumstancesof acute injury to tissues of the body, it is currently popular
to incriminate byproducts of oxygen metab- olism as the ultimate injurious
agents. A disparate array ofcon- ditions is encompassed in thisconcept, ...
Cited by 471 - Related articles - All 6 versions

Human neutrophil antimicrobial activity


EL Thomas, RI Lehrer, RF Rest - Reviews of Infectious Diseases, 1988 - jstor.org
Fusion of cytoplasmic granules of polymorphonu- clear neutrophilic leukocytes
(PMNs) with phago- somes is accompanied by assembly and activation of an NADPH
oxidase in the phagolysosome mem- brane. The oxidase spans the membrane and ...
Cited by 74 - Related articles - All 2 versions

The role of extracellular bactericidal factors in pulmonary host defense.


JD Coonrod - Seminars in respiratory infections, 1986 - ncbi.nlm.nih.gov
Extracellular killing provides an attractive hypothesis to explain the rapid
alveolar killing of inhaled bacterial pathogens in the absence of conventional
opsonins for phagocytosis. Some evidence of extracellular killing of ...
Cited by 38 - Related articles

Spontaneous and Fas-induced apoptotic cell death in aged neutrophils


C Tortorella, G Piazzolla, F Spaccavento, S … - Journal of clinical immunology, 1998 - Springer
On the basis of the strict analogies between polymorphonuclear cell (PMN)
alterations in the aging and depressed functional capacities displayed by
apoptotic PMN, we investigated the possible occurrence of age-associated ...
Cited by 42 - Related articles - BL Direct - All 5 versions

Changes in apoptosis of human polymorphonuclear granulocytes with aging


T Fülöp Jr, C Fouquet, P Allaire, N Perrin, … - Mechanisms of ageing and development, 1997 - Elsevier
Many alterations with aging occur at the cellular and organic levels in the
immune system ultimately leading to a decrease in the immune response. Our aim
in the present work was to study apoptosis of polymorphonuclear ...
Cited by 55 - Related articles - All 5 versions

Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes.

- nih.gov [PDF] 
T Ganz - Infection and Immunity, 1987 - Am Soc Microbiol
INFECTION AND IMMUNITY, Mar. 1987, p. 568-571 0019-9567/87/030568-04$02.00/0
Copyright C) 1987, American Society for Microbiology ... TOMAS GANZ Department
ofMedicine, Centerfor the Health Sciences, University of California at Los ...
Cited by 139 - Related articles - All 8 versions

Antibiotic proteins of human neutrophils.

- nih.gov [PDF] 
JK Spitznagel - Journal of Clinical Investigation, 1990 - pubmedcentral.nih.gov
Introduction Despite strenuous opposition, Ilya Metchnikov convinced the
scientific world 110 years ago that phagocytosis has a major role in immunity to
infection (1).' Metchnikov conjectured that phagocytes destroy microbes ...
Cited by 109 - Related articles - All 5 versions

Age-related alterations in actin cytoskeleton and receptor expression in human leukocytes


K Rao, MS Currie, J Padmanabhan, HJ … - The Journal of Gerontology, 1992 - geronj.oxfordjournals.org
Page 1. Journal of Gerontology: BIOLOGICAL SCIENCES 1992, Vol.47, No. 2,
B37-44 Copyright 1992 by The Gerontological Society of America ...
Cited by 21 - Related articles - All 3 versions


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