- ►nih.gov [PDF] DW Rahn, SE Malawista - Western Journal of Medicine, 1991 - pubmedcentral.nih.gov Lyme disease is a tick-borne immune-mediated inflam- matory disorder caused by a newly recognized
spiro- chete, Borrelia burgdorferi. Over the past 15 years it has progressed from a medical curiosity
to the most frequently recognized vector-borne illness in the United States. Its clini- cal ... Cited by 227 - Related articles - BL Direct - All 11 versions
EM Massarotti, SW Luger, DW Rahn, RP Messner, … - The American journal of …, 1992 - Elsevier : Fifty-five patients with erythema migrans and two patients with flu-like symptoms alone and
fourfold changes in antibody titers to Borrelia burgdorferi were randomized to receive (1) oral
azithromycin, 500 mg on the first day followed by 250 mg once a day for 4 days; (2) oral ... Cited by 108 - Related articles - All 5 versions
AC STEERE, RT SCHOEN, E TAYLOR - Annals of internal medicine, 1987 - Am Coll Physicians To determine the clinical evolution of Lyme arthritis, 55 patients who did not receive antibiotic
therapy for erythema chronicum migrans were followed longitudinally for a mean duration of
6 years. Of the 55 patients, 11 (20%) had no subsequent manifestations of Lyme disease. ... Cited by 378 - Related articles - All 3 versions
RJ Dattwyler, DJ Volkman, SM Conaty, SP Platkin, BJ … - The Lancet, 1990 - Elsevier 72 adults with erythema migrans (early Lyme borreliosis) were enrolled in a randomised prospective
trial comparing amoxycillin 500 mg plus probenecid 500 mg three times a day with doxycycline
100 mg twice a day for 21 days. These antibiotic regimens were chosen because of the ... Cited by 97 - Related articles - All 6 versions
… , JH NEWMAN, DW RAHN, LH SIGAL, PN … - Annals of Internal …, 1983 - Am Coll Physicians Lyme disease, caused by a tick-transmitted spirochete, typically begins with a unique skin
lesion, erythema chronicum migrans. Of 314 patients with this skin lesion, almost half developed
multiple annular secondary lesions; some patients had evanescent red blotches or ... Cited by 468 - Related articles - All 5 versions
BW Stechenberg - Pediatric Infectious Disease Journal, 1988 - pdfs.journals.lww.com Vol. 7, No. 6 STECHENBERG 403 shore.10 Case-control studies of patients, mainly chil- dren
and young adults, and their neighbors revealed that patients did not have more outdoor activities
but were more likely to have a cat or farm animal, a pet with ticks or a tick bite in the year ... Cited by 26 - Related articles - All 5 versions
BS Schwartz, MD Goldstein, JM Ribeiro, TL Schulze, SI … - JAMA, 1989 - Am Med Assoc To evaluate the interlaboratory and intralaboratory agreement in the performance of Lyme disease
serological testing, we sent serum specimens from 132 outdoor workers in New Jersey to as
many as four independent laboratories. These included one state department of health ... Cited by 97 - Related articles - All 4 versions
RB Nadelman, SW Luger, E Frank, M … - Annals of internal …, 1992 - Am Coll Physicians Objective: To compare the efficacy of cefuroxime axetil and doxycycline in the treatment of patients
with Lyme disease associated with erythema migrans. ... Design: Randomized, multicenter, investigatorblindedclinical
trial with clinical evaluations during treatment (8 to 12 days) and at 1 to 5 days and 1, 3, 6, ... Cited by 108 - Related articles - All 3 versions
AC Steere, E Taylor, GL McHugh, EL Logigian - Jama, 1993 - Am Med Assoc OBJECTIVE--To analyze the diagnoses, serological test results, and treatment results of the patients
evaluated in a Lyme disease clinic, both prior to referral and from current evaluation.
DESIGN--Retrospective case survey of prescreened patients. SETTING--Research and ... Cited by 250 - Related articles - BL Direct - All 3 versions
ED Shapiro, MA Gerber, NB Holabird, AT … - New England Journal …, 1992 - content.nejm.org BACKGROUND. Borrelia burgdorferi, which causes Lyme disease, is transmitted by deer ticks
(lxodes dammini) in the northeastern and midwestern United States. Although deer-tick bites
are common in areas in which the disease is endemic, there is uncertainty about how to ... Cited by 124 - Related articles - BL Direct - All 4 versions
