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Scholar Results 1 - 10 of about 101 related to Gelber: Quality-of-life evaluation in a clinical trial of zidovudine therapy in patients.... (0.09 sec) 

Quality-of-life evaluation in a clinical trial of zidovudine therapy in patients with …


RD Gelber, WR Lenderking, DJ Cotton, BF … - Annals of Internal …, 1992 - Am Coll Physicians
▪ Objective: To evaluate the effects of zidovudine therapy in patients with mildly symptomatic
HIV infection using Q-TWiST (quality-adjusted: Time Without Symptoms and Toxicity). ...
Design: Analysis of a previously reported multicenter, randomized, placebo-controlled ...
Cited by 67 - Related articles - All 4 versions

Evaluation of the quality of life associated with zidovudine treatment in …


WR Lenderking, RD Gelber, DJ Cotton, BF … - New England Journal …, 1994 - content.nejm.org
Results The average time with neither a progression of disease nor an adverse event (symptom
or laboratory finding) was 15.7, 15.6, and 14.8 months for patients receiving placebo, 500 mg
of zidovudine, and 1500 mg of zidovudine, respectively. The incidence of severe ...
Cited by 117 - Related articles - BL Direct - All 5 versions

Quality of life in a placebo-controlled trial of zidovudine in patients with AIDS and …


AW Wu, WC Mathews, LT Brysk, JH Atkinson, … - JAIDS Journal of …, 1990 - journals.lww.com
Journal of Acquired Immune Deficiency Syndromes 3:683-690 © 1990 Raven Press, Ltd., New
York Quality of Life in a Placebo-Controlled Trial of Zidovudine in Patients with AIDS and
AIDS-Related Complex *Albert W. Wu, *William С Mathews, tLucy T. Brysk, tHJ. Hampton ...
Cited by 99 - Related articles - All 2 versions

Functional Status and Weil-Being in a Placebo-Controlled Trial of Zidovudine in …


AW Wu, HR Rubin, WC Mathews, LM Brysk, … - JAIDS Journal of …, 1993 - journals.lww.com
Summary: To determine the effect of zidovudine on functional status and well-being in patients
with early symptomatic human immunodeficiency virus (HIV) infection, 70 subjects in a
randomized, placebo-controlled trial (ACTG Protocol 016) were observed for 1 year using ...
Cited by 61 - Related articles - BL Direct - All 3 versions

Quality-of-life-adjusted evaluation of adjuvant therapies for operable breast cancer


RD Gelber, A Goldhirsch, F Cavalli - Annals of internal medicine, 1991 - Am Coll Physicians
Objective: To evaluate a single cycle of adjuvant chemotherapy compared with longer duration
chemotherapy for premenopausal women or chemoendocrine therapy for postmenopausal women
with operable breast cancer using a quality-of-life-oriented end point, Q-TWiST (quality- ...
Cited by 100 - Related articles - All 4 versions

Health-related quality of life in persons with acquired immune deficiency syndrome


PD Cleary, FJ Fowler Jr, J Weissman, MP Massagli, I … - Medical care, 1993 - jstor.org
Page 1. MEDICAL CARE Volume 31, Number 7, pp 569-580 ? 1993, JB Lippincott Company
Health-Related Quality of Life in Persons with Acquired Immune Deficiency Syndrome
PAUL D. CLEARY, PHD,*'t'' ? FLOYD J. FOWLER, JR., PHD,?, ...
Cited by 111 - Related articles - BL Direct - All 4 versions

Changes in quality of life among persons with HIV infection


DP Lubeck, JF Fries - Quality of Life Research, 1992 - Springer
Health-related quality of life (QOL) is an important component of the evaluation of patient outcome
in HIV infection where disease is progressive and debilitating. This paper compares patient-reported
QOL obtained from questionnaires which cover func- tional ability, social functioning, ...
Cited by 83 - Related articles - All 3 versions

Describing the health-related quality of life impact of HIV infection: Findings from a …


PA Ganz, CAC Schag, B Kahn, L Petersen, K Hirji - Quality of Life Research, 1993 - Springer
PA Ganz,* CA Coscarelli Schag, 6. Kahn, L. Petersen and K. Hirji Department of Medicine, UCLA
School of Medicine (PA Ganz, CA Coscarelli Schag), Department of Health Services, UCLA School
of Public Health (PA Ganz), Division of Cancer Control, Jonsson Comprehensive Cancer ...
Cited by 57 - Related articles - All 3 versions

Quality of life in clinical trials of adjuvant therapies. International Breast Cancer …


RD Gelber, A Goldhirsch, C Hürny, J … - Journal of the National …, 1992 - ncbi.nlm.nih.gov
Clinical trials of adjuvant therapies usually measure the effectiveness of treatments by comparing
disease-free survival or overall survival. These take into consideration only indirectly the quality
of life experienced by the patients. We present some approaches that were developed to ...
Cited by 19 - Related articles - BL Direct - All 2 versions

Comparing treatments using quality-adjusted survival: The Q-TWiST method


RD Gelber, BF Cole, S Gelber, A Goldhirsch - The American Statistician, 1995 - questia.com
The evaluation of treatments in terms of quality of life is becoming increasingly important in clinical
research (Schumacher, Olschewski, and Schulgen 1991; Cox et al. 1992). In particular, there
is a need to develop methods for comparing the palliative effects of treatment options ...
Cited by 64 - Related articles - BL Direct - All 4 versions


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