MB Sporn, AB Roberts - Annals of internal medicine, 1992 - Am Coll Physicians Add to CiteULike Add to Complore Add to Connotea Add to Del.icio.us Add to Digg Add to Facebook Add
to Reddit Add to Technorati Add to Twitter What's this? ... From the National Cancer Institute,
Bethesda, Maryland. For current ... Cited by 121 - Related articles - All 3 versions
… , GT Oehrtman, L Walker, HS Wiley - Proceedings of the …, 1998 - National Acad Sciences Autocrine ligands are important regulators of many normal tissues and have been implicated in a
number of disease states, including cancer. However, because by definition autocrine ligands are
synthesized, secreted, and bound to ... Cited by 36 - Related articles - BL Direct - All 9 versions
- ►nih.gov [PDF] KE Forsten, DA Lauffenburger - Biophysical journal, 1992 - Elsevier Autocrine ligands have been demonstrated to regulate cell proliferation, cell adhesion, and cell
migration in a number of different systems and are believed to be one of the underlying causes of
malignant cell transformation. ... Cited by 27 - Related articles - All 7 versions
GT Oehrtman, HS Wiley, DA … - Biotechnology and …, 1998 - interscience.wiley.com We have developed an experimental system for testing mathematical model predictions concerning
escape of autocrine ligands into the extracellular bulk medium. This system employs anti-receptor
blocking antibodies against the ... Cited by 26 - Related articles - BL Direct - All 6 versions
KE FORSTEN, DA LAUFFENBURGER - Journal of Computational …, 1994 - liebertonline.com Page 1. Probability of Autocrine Ligand Capture by Cell-Surface Receptors: Implications for Ligand
Secretion Measurements KIMBERLY E. FORSTEN and DOUGLAS A. LAUFFENBURGER ABSTRACT Autocrine ligands regulate
important cell behavioral functions in both physiological and pathological conditions. ... Cited by 19 - Related articles - All 3 versions
- ►nih.gov [PDF] KE Forsten, DA Lauffenburger - Biophysical journal, 1992 - Elsevier Stimulation of cell behavioral functions by ligand/receptor binding can be accomplished in autocrine
fashion, where cells secrete ligand capable of binding to receptors on their own surfaces. This
proximal secretion of autocrine ... Cited by 17 - Related articles - All 11 versions
BH Will, DA Lauffenburger, HS Wiley - Tissue Engineering, 1995 - liebertonline.com Page 1. TISSUE ENGINEERING Volume 1, Number 1, 1995 Mary Ann Liebert, Inc., Publishers Studies on
Engineered Autocrine Systems: Requirements for Ligand Release from Cells Producing an Artificial Growth
Factor BIRGIT H. WILL, Ph.D., 1 DOUGLAS A. LAUFFENBURGER, Ph.D., 2 and H. STEVEN WILEY, Ph.D. 1 ... Cited by 13 - Related articles - All 2 versions
- ►rupress.org HS Wiley, MF Woolf, LK Opresko, PM Burke, B … - Journal of Cell …, 1998 - jcb.rupress.org Autocrine EGF-receptor (EGFR) ligands are normally made as membrane-anchored precursors that are
proteolytically processed to yield mature, soluble peptides. To explore the function of the
membrane-anchoring domain of EGF, ... Cited by 43 - Related articles - BL Direct - All 8 versions
- ►biologists.org AE DeWitt, JY Dong, HS Wiley, DA … - Journal of Cell …, 2001 - jcs.biologists.org Autocrine signaling is important in normal tissue physiology as well as pathological conditions. It
is difficult to analyze these systems, however, because they are both self-contained and recursive.
To understand how parameters such ... Cited by 43 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] SY Shvartsman, HS Wiley, WM Deen, DA … - Biophysical Journal, 2001 - Elsevier Autocrine loops formed by growth factors and their receptors have been identified in a large number
of developmental, physiological, and pathological contexts. In general, the spatially distributed
and recursive nature of autocrine ... Cited by 63 - Related articles - BL Direct - All 13 versions
