E Israel, P Rubin, JP Kemp, J Grossman, W … - Annals of internal medicine, 1993 - Am Coll Physicians Add to CiteULike Add to Complore Add to Connotea Add to Del.icio.us Add to Digg
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Objective: To evaluate the effectiveness of inhibiting the formation of the ... Cited by 226 - Related articles - BL Direct - All 4 versions
E Israel, R Dermarkarian, M Rosenberg, R … - New England Journal of Medicine, 1990 - content.nejm.org BACKGROUND. The enzyme 5-lipoxygenase catalyzes the metabolism of arachidonic
acid to form products that have been implicated in the airway obstruction of
asthma. We hypothesized that if products of the 5-lipoxygenase pathway are ... Cited by 231 - Related articles - All 4 versions
SL Spector, LJ Smith, M Glass - American journal of respiratory and critical care …, 1994 - 171.66.122.149 The efficacy of 6 wk of therapy with oral ICI 204,219, a selective leukotriene
D4 (LTD4) receptor antagonist, was evaluated in subjects with moderate asthma
during a multicenter, double-blind, randomized, placebo-controlled, ... Cited by 207 - Related articles - BL Direct - All 5 versions
E Israel, AR Fischer, MA Rosenberg, CM Lilly, … - The American review of respiratory disease, 1993 - ncbi.nlm.nih.gov 1: Am Rev Respir Dis. 1993 Dec;148(6 Pt 1):1447-51. The pivotal role of 5-lipoxygenase
products in the reaction of aspirin-sensitive asthmatics to aspirin. ... Cited by 256 - Related articles - BL Direct - All 2 versions
- ►nih.gov [PDF] KP Hui, IK Taylor, GW Taylor, P Rubin, J … - British Medical Journal, 1991 - thorax.bmj.com Abstract The effect of a single oral dose (800 mg) of zileuton (A-64077), a
specific 5-lipoxy- genase inhibitor, on the early and late airway responses to
inhaled allergen was studied in a randomised, double blind, placebo ... Cited by 99 - Related articles - All 7 versions
IK Taylor, KM O'shaughnessy, RW Fuller, CT … - Lancet, 1991 - ncbi.nlm.nih.gov The effects of a highly selective leukotriene D4 receptor antagonist, ICI
204.219, on allergen-induced bronchoconstriction and changes in airway
reactivity were evaluated in a double-blind, placebo-controlled, crossover ... Cited by 287 - Related articles - All 5 versions
E Israel, J Cohn, L Dube, JM Drazen - Jama, 1996 - Am Med Assoc OBJECTIVE: To study the effect of 3 months of treatment with zileuton, an
inhibitor of the enzymatic pathway (5-lipoxygenase) leading to leukotriene
formation, on disease control in patients with mild to moderate asthma. ... Cited by 178 - Related articles - BL Direct - All 6 versions
KP Hui, NC Barnes - Lancet, 1991 - ncbi.nlm.nih.gov In a double-blind study ten asthmatic patients with impaired lung function
received the cysteinyl-leukotriene receptor antagonist ICI 204,219 (40 mg by
mouth) and placebo in random order on 2 days at least 1 week apart. The ... Cited by 156 - Related articles - All 4 versions
JN Gaddy, DJ Margolskee, RK Bush, VC … - The American review of respiratory disease, 1992 - be-md.ncbi.nlm.nih.gov 1: Am Rev Respir Dis. 1992 Aug;146(2):358-63. Bronchodilation with a potent
and selective leukotriene D4 (LTD4) receptor antagonist ... Cited by 103 - Related articles - All 4 versions
PJ Manning, RM Watson, DJ Margolskee, VC … - New England Journal of Medicine, 1990 - content.nejm.org BACKGROUND. Exercise is a common stimulus of bronchoconstriction in subjects
with asthma, who also have bronchoconstriction after inhaling the sulfidopeptide
leukotriene D4 (LTD4). The purpose of this study was to investigate the ... Cited by 251 - Related articles - All 5 versions
