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Scholar Results 1 - 10 of about 101 related to Natanson: Selected treatment strategies for septic shock based on proposed mechanisms of.... (0.12 sec) 

Selected treatment strategies for septic shock based on proposed mechanisms of …

- annals.org
C Natanson, WD Hoffman, AF Suffredini, PQ … - Annals of Internal Medicine, 1994 - Am Coll Physicians
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Purpose: To review selected new therapies for septic shock designed to ...
Cited by 417 - Related articles - BL Direct - All 3 versions

Gram-negative bacterial sepsis and the sepsis syndrome


V Lazaron, RA Barke - Urologic Clinics of North America, 1999 - Elsevier
The incidence of serious infection in hospitalized patients has increased over
the last 3 decades. These infections have major consequences in morbidity,
mortality, and increased medical expenditures. Particular attention has ...
Cited by 16 - Related articles - BL Direct - All 13 versions

Anti-inflammatory therapies to treat sepsis and septic shock: a reassessment


F Zeni, B Freeman, C Natanson - Critical care medicine, 1997 - journals.lww.com
This issue of Critical Care Medicine reports the results of the second phase III
double-blinded multicenter trial of interleukin-1 receptor antagonist (IL-1ra)
[1] . In a clear presentation and discussion of the data, Dr. Opal and ...
Cited by 568 - Related articles - BL Direct - All 4 versions

Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients …


E Abraham, R Wunderink, H Silverman, TM … - Jama, 1995 - Am Med Assoc
OBJECTIVE--To evaluate the efficacy and safety of anti-tumor necrosis factor
alpha monoclonal antibody (TNF-alpha MAb) in the treatment of patients with
sepsis syndrome. DESIGN--Randomized, prospective, multicenter, ...
Cited by 580 - Related articles - BL Direct - All 3 versions

Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein


CJ Fisher, JM Agosti, SM Opal, SF Lowry, RA … - New England Journal of Medicine, 1996 - content.nejm.org
Methods To evaluate the safety and efficacy of TNFR:Fc in the treatment of
septic shock, we conducted a randomized, double-blind, placebo-controlled,
multicenter trial. A total of 141 patients were randomly assigned to ...
Cited by 767 - Related articles - BL Direct - All 7 versions

[CITATION] Septic Shock: Mechanisms, Cardiovascular Abnormalities, and New


T Approaches - The Critically Ill Cardiac Patient: Multisystem …, 1996 - Lippincott Williams & Wilkins
Related articles

Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody …

- critcaremed.org
K Reinhart, C Wiegand-Lohnert, F Grimminger, … - Critical care medicine, 1996 - journals.lww.com
From the Department of Anaesthesiology and Operative Intensive Care (Dr.
Reinhart), Friedrich-Schiller-University, Jena, Germany; Steglitz University
Medical Centre (Dr. Wiegand-Lohnert), Berlin, Germany; Department of ...
Cited by 245 - Related articles - BL Direct - All 4 versions

New strategies for combatting sepsis: The magic bullets missed the mark… but the search …


ZMN Quezado, SM Banks, C Natanson - Trends in Biotechnology, 1995 - Elsevier
Despite the high expectations of scientists and industry, multiple clinical
trials of anti-endotoxin- and anti-cytokine-based therapies for sepsis have
failed to demonstrate benefit. Indeed, in some cases, the agents used were ...
Cited by 50 - Related articles - All 5 versions

A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the …


RL Greenman, RM Schein, MA Martin, RP … - Jama, 1991 - Am Med Assoc
OBJECTIVE: To assess the efficacy of adjunctive monoclonal antibody
antiendotoxin immunotherapy in patients with gram-negative sepsis. DESIGN:
Double-blind, randomized, placebo-controlled trial. SETTING: Thirty-three ...
Cited by 503 - Related articles - All 3 versions

Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis …


CJ Fisher Jr, JFA Dhainaut, SM Opal, JP … - Jama, 1994 - Am Med Assoc
Charles J. Fisher, Jr, MD; Jean-Francois A. Dhainaut, MD, PhD; Steven M. Opal,
MD; John P. Pribble, PharmD; Robert A. Balk, MD; Gus J. Slotman, MD; Thomas J.
Iberti, MD; Eric C. Rackow, MD; Marc J. Shapiro, MD; Richard L. Greenman, ...
Cited by 626 - Related articles - BL Direct - All 4 versions


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