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Scholar Results 1 - 10 of about 101 related to Chiasson: The efficacy of acarbose in the treatment of patients with non-insulin-dependent.... (0.08 sec) 

The efficacy of acarbose in the treatment of patients with non-insulin-dependent diabetes …

- annals.org
JL Chiasson, RG Josse, JA Hunt, C Palmason … - Annals of internal medicine, 1994 - Am Coll Physicians
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Objective: To evaluate the long-term efficacy of acarbose, an -glucosidase ...
Cited by 354 - Related articles - BL Direct - All 6 versions

Multicenter, placebo-controlled trial comparing acarbose (BAY g 5421) with placebo, …


RF Coniff, JA Shapiro, TB Seaton, GA Bray - The American Journal of Medicine, 1995 - Elsevier
All active treatments were superior (P <0.05) to placebo in reducing
postprandial hyperglycemia and HbA 1c levels. The ranking in order of efficacy
was: acarbose-plus-tolbutamide, tolbutamide, acarbose, and placebo. The ...
Cited by 104 - Related articles - BL Direct - All 7 versions

Efficacy of 24-week monotherapy with acarbose, glibenclamide, or placebo in NIDDM …


J Hoffmann, M Spengler - Diabetes Care, 1994 - Am Diabetes Assoc
OBJECTIVE--To compare the different therapeutic principles of alpha-glucosidase
inhibitors and sulphonylureas as first-line treatment in non-insulin-dependent
diabetes mellitus (NIDDM) patients with dietary failure. RESEARCH DESIGN ...
Cited by 101 - Related articles - BL Direct - All 10 versions

A double-blind placebo-controlled trial evaluating the safety and efficacy of acarbose for the …


RF Coniff, JA Shapiro, TB Seaton, BJ … - Diabetes Care, 1995 - Am Diabetes Assoc
OBJECTIVE--To determine whether a forced titration of acarbose (from 50 to 300
mg three times daily) administered over a 24-week period, in conjunction with
diet and insulin therapy, improves glycemic control and reduces daily ...
Cited by 74 - Related articles - BL Direct - All 5 versions

Therapeutic potentials of acarbose as first-line drug in NIDDM insufficiently treated with diet …


M Hanefeld, S Fischer, J Schulze, M Spengler … - Diabetes Care, 1991 - Am Diabetes Assoc
OBJECTIVE: Acarbose inhibits alpha-glucosidases of the small intestine and thus
delays glucose release from complex carbohydrates. Therefore, its efficacy and
acceptability as a first-line drug in non-insulin-dependent diabetes ...
Cited by 120 - Related articles - All 6 versions

Reduction of glycosylated hemoglobin and postprandial hyperglycemia by acarbose in …


RF Coniff, JA Shapiro, D Robbins, R … - Diabetes Care, 1995 - Am Diabetes Assoc
OBJECTIVE--To compare the safety and efficacy of three doses of acarbose (100,
200, and 300 mg three times daily) with placebo for the treatment of
non-insulin-dependent diabetes mellitus (NIDDM) in patients maintained on ...
Cited by 107 - Related articles - BL Direct - All 6 versions

Long-term Efficacy and Safety of Acarbose in the Treatment of Obese Subjects With Non-- …


RF Coniff, JA Shapiro, TB Seaton - Archives of Internal Medicine, 1994 - archinte.highwire.org
Background:Acarbose delaysthe release ofglucosefrom complex carbohydrates and
disaccharides by inhibiting intestinal \g=a\-glucosidases,attenuating
postprandial in- crements in blood glucose and insulin. This multicenter ...
Cited by 60 - Related articles - BL Direct - All 5 versions

Efficacy and safety of acarbose in insulin-treated patients with type 2 diabetes.

- diabetesjournals.org [PDF] 
DE Kelley, P Bidot, Z Freedman, B Haag, D … - Diabetes Care, 1998 - Am Diabetes Assoc
It can be difficult to control postprandial hype rglycemia in patients with type
2 diabetes. Impaired insulin secretion, par- ticularly during the early prandial
phase, is a key factor in an inefficient prandial sup- p ression of ...
Cited by 69 - Related articles - BL Direct - All 6 versions

A randomized double-blind trial of acarbose in type 2 diabetes shows improved glycemic …

- diabetesjournals.org [PDF] 
RR Holman, CA Cull, RC Turner - Diabetes Care, 1999 - Am Diabetes Assoc
Patients Of 3,309 patients attending UKPDS clinics (8) between May and September
1994, 1,946 (59%) agreed to take part in a 3-year, double-blind,
placebo-controlled trial of acarbose given in addition to their pre e x- ...
Cited by 193 - Related articles - BL Direct - All 8 versions

Therapeutic comparison of metformin and sulfonylurea, alone and in various combinations. A …


LS Hermann, B Schersten, PO Bitzen, T … - Diabetes Care, 1994 - Am Diabetes Assoc
OBJECTIVE--To assess and compare the therapeutic efficacy and safety of
metformin (M) and sulfonylurea (glyburide, G), alone and in various
combinations, in patients with non-insulin-dependent diabetes mellitus ...
Cited by 233 - Related articles - BL Direct - All 7 versions


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