- ►annals.org JI Gallin, JM Farber, SM Holland, TB Nutman - Annals of internal medicine, 1995 - Am Coll Physicians Interferon- has pleiotropic adjuvant effects on host defenses. These effects
have made interferon- particularly useful for enhancing host defenses in
patients with chronic granulomatous disease of childhood and thus for ... Cited by 105 - Related articles - BL Direct - All 3 versions
HW Murray - The American journal of medicine, 1994 - Elsevier In the 1980s, substantive experimental data and emerging clinical results
suggested that interferon-gamma (IFN-γ), a T-cell-derived lymphokine with broad
macrophage-activating effects, had considerable potential in the treatment ... Cited by 103 - Related articles - BL Direct - All 4 versions
SM Holland, EM Eisenstein, DB Kuhns, ML … - The New England journal of medicine, 1994 - nejm.highwire.org Methods We studied seven patients with refractory disseminated nontuberculous
mycobacterial infections who were not infected with the human immunodeficiency
virus. Three patients were from a family predisposed to the development of ... Cited by 220 - Related articles - BL Direct - All 5 versions
HW Murray - Intensive care medicine, 1996 - Springer Abstract The T cell-derived macro- phage-activating lymphokine, interfer-
on-gamma (IFN-?), is the most broadly acting antimicrobial-inducing and host
defense-enhancing cytokine thus far identified in experimental models of ... Cited by 45 - Related articles - BL Direct - All 4 versions
- ►bloodjournal.org DE Schiff, J Rae, TR Martin, BH Davis, JT … - Blood, 1997 - Am Soc Hematology Recombinant human interferon- (rhIFN- ) decreases the frequency of serious
infections in patients with chronic granulomatous disease (CGD) through an
unknown mechanism. To test the hypothesis that it exerts a beneficial ... Cited by 44 - Related articles - BL Direct - All 4 versions
TW Chin, ER Stiehm, J Falloon, JI Gallin - The Journal of pediatrics, 1987 - Elsevier Two patients with chronic granulomatous disease had obstructive lesions of the
gastrointestinal tract, esophagus, and genitourinary tract, which were
successfully treated with corticosteroids. These obstructive lesions, ... Cited by 80 - Related articles - All 8 versions
SH Jackson, GF Miller, BH Segal, M Mardiney … - Journal of Interferon & Cytokine Research, 2001 - liebertonline.com Chronic granulomatous disease (CGD) is a genetic disorder characterized by
recurrent bacterial and fungal infections and tissue granuloma formation. CGD
phagocytes are unable to generate superoxide because of mutations in any of ... Cited by 23 - Related articles - BL Direct - All 3 versions
MM Walther, H Malech, A Berman, P Choyke, … - The Journal of urology, 1992 - cat.inist.fr The urological manifestations of chronic granulomatous disease. MM WALTHER,
H MALECH, A BERMAN, P CHOYKE, DJ VENZON, WM LINEHAN, JI ... Cited by 30 - Related articles - All 2 versions
CF Nathan, G Kaplan, WR Levis, A Nusrat, … - New England Journal of Medicine, 1986 - content.nejm.org Evidence that interferon-gamma may be a physiologic macrophage-activating
factor, and that macrophage activation may be defective in lepromatous leprosy,
led us to test the effects of intradermal injection of low doses of ... Cited by 209 - Related articles - All 3 versions
JI Gallin, ES Buescher - Inflammation, 1983 - Springer Abstract--A common characteristic of the response to izffection seen in patients
with chronic gmnulomatous disease (CGD) is an exaggerated and prolonged in-
flammatory response with frequent development of draining lymph nodes and ... Cited by 36 - Related articles - All 2 versions
