DT Price, PM Ridker - Annals of Internal Medicine, 1997 - Am Coll Physicians Background: A single point mutation in the gene coding for coagulation factor V results in a form
of factor Va that is resistant to degradation by activated protein C and leads to a relative hypercoagulable
state. This mutation, factor V Leiden, is found in 4% to 6% of the US population. Cited by 241 - Related articles - BL Direct - All 7 versions
ДТ Прайс, ПМ Ридкер - Ann. Intern. Med.–1997.–127.–P - mediasphera.ru Точечная мутация гена, кодирующего V фактор свертывания крови, приводит к тому, что
активированная форма фактора V (Va) становится устойчивой к расщепляющему действию
активированного протеина С, и возникает состояние относительной ... Related articles
PM Ridker, JP Miletich, CH Hennekens, JE Buring - Jama, 1997 - Am Med Assoc OBJECTIVE: To estimate ethnic-specific prevalence rates of factor V Leiden, an inherited defect
of hemostasis associated with risk of venous thrombosis. DESIGN: Survey of 4047 American
men and women participating in the Physicians' Health Study (PHS) or in the Women's ... Cited by 391 - Related articles - BL Direct - All 4 versions
- ►annals.org PM Ridker, RJ Glynn, JP Miletich, SZ … - Annals of internal …, 1997 - Am Coll Physicians Add to CiteULike Add to Complore Add to Connotea Add to Del.icio.us Add to Digg Add to Facebook
Add to Reddit Add to Technorati Add to Twitter What's this? ... Background: Previous reports
suggest that younger carriers of the factor V Leiden mutation are at greater risk for venous ... Cited by 122 - Related articles - BL Direct - All 4 versions
B Dahlbäck - ishapd.org Procoagulant factors, which activate platelets and initiate blood coagulation, are exposed upon
vascular damage. (1,2) In a series of sequential proteolytic reactions, proenzymes are
activated, culminating in the formation of thrombin. Several of the reactions are greatly ... Related articles - View as HTML - All 2 versions
GA Otterson, BP Monahan, N Harold, SM Steinberg … - The American Journal of …, 1996 - Elsevier We detected a germline mutation in 5.4% (19 of 353) of patients, of whom 18 were heterozygous
and 1 was homozygous for the FY-Q 506 mutant allele. In 17 of 18 heterozygous patients, there
was no history of venous thrombosis or catheter-associated thrombosis. These ... Cited by 32 - Related articles - BL Direct - All 5 versions
R I. Baker, John Eikelboom, Alison Street - Pathology, 1999 - informahealthcare.com *Clinical Thrombosis Unit, Haematology Department, Royal Perth Hospital, University of Western
Australia, Perth, Australia; †The Preventive Cardiology and Therapeutics Program, McMaster
University, Canada and ‡Haematology Department, Alfred Hospital, Melbourne, Australia Related articles - All 6 versions
- ►ahajournals.org PM Ridker, JP Miletich, MJ Stampfer, SZ Goldhaber, K … - Circulation, 1995 - Am Heart Assoc Methods and Results Among 14 916 apparently healthy men who provided DNA samples and
were followed in the Physicians' Health Study through August 1994, 77 suffered an idiopathic
VTE. These 77 men were followed for an additional average period of 68.3 months, ... Cited by 226 - Related articles - BL Direct - All 5 versions
V Thrombosis - origin.cdc.gov Following myocardial infarction and stroke, venous thromboembolism (VTE) is the third most
common cardiovascular disease in the United States. The mortality and morbidity of VTE is significant
with an annual incidence of approximately 1:1000 individuals and pulmonary embolism is ... Related articles - Cached - All 3 versions
