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Scholar Results 1 - 10 of about 101 related to Strober: The pathogenesis of mucosal inflammation in murine models of inflammatory bowel.... (0.10 sec) 

The pathogenesis of mucosal inflammation in murine models of inflammatory …

- annals.org
W Strober, BR Ludviksson, IJ Fuss - Annals of internal medicine, 1998 - Am Coll Physicians
In recent years, it has become apparent that overproduction of the Th1 cytokines interleukin-12
and interferon- is the probable driving force behind murine models of intestinal inflammation
resembling Crohn disease and intestinal inflammation in humans with Crohn disease. In ...
Cited by 114 - Related articles - BL Direct - All 3 versions

The Role of IL-10 in Inflammatory Bowel Disease:" Of Mice and Men"

- sagepub.com [PDF] 
MW Leach, NJ Davidson, MM Fort, F Powrie, DM … - Toxicologic …, 1999 - tpx.sagepub.com
The Role of IL-10 in Inflammatory Bowel Disease: ... MICHAEL W. LEACH, 1 NATALIE J.
DAVIDSON, 2 MADELINE M. FORT, 2 ... FIONA POWRIE, 3 AND DONNA M. RENNICK 2 ...
1 Schering-Plough Research Institute, Lafayette, New Jersey 07848,
Cited by 39 - Related articles - BL Direct - All 3 versions

Concepts in the treatment of experimental granulomatous colitis with Th1 inhibitory …


IJ Fuss, T Marth, W Strober, M Neurath - Induction and modulation of …, 1999 - books.google.com
15 Concepts in the treatment of experimental granulomatous colitis with Th1 inhibitory therapeutic
modalities IJ FUSS, T. MARTH, W. STROBER and M. NEURATH INTRODUCTION Inflammatory
bowel disease (IBD) encompasses Crohn's disease (CD) and ulcerative colitis, the ...
Related articles - BL Direct

Inflammatory bowel diseases: a breakdown of central and peripheral …


W Strober, RO Ehrhardt, BR Ludviksson - Induction and modulation …, 1999 - books.google.com
10 Inflammatory bowel diseases: a breakdown of central and peripheral immunological homeostasis
W. STROBER, RO EHRHARDT AND BR LUDVIKSSON INTRODUCTION: GENERALIZATIONS
CONCERNING MOUSE MODELS OF MUCOSAL INFLAMMATION Until recently, ...
Cited by 1 - Related articles - BL Direct

Induction of colitis in IL2-deficient-mice: the role of thymic and peripheral …


RO Ehrhardt, B Ludviksson - Research in Immunology, 1997 - Elsevier
[see comments]P. Mombaerts et al., Spontaneous development of inflammatory bowel disease
in T cell recep-tor mutant mice, Cell 75 (1993) (2), pp. 274–282. ... W. Strober and SP
James, The immunopathogenesis of gastrointestinal and hepatobiliary dis-eases, Jama ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Oxazolone colitis: a murine model of T helper cell type 2 colitis treatable with …

- nih.gov
M Boirivant, IJ Fuss, A Chu, W Strober - Journal of experimental …, 1998 - jem.rupress.org
In this study we describe oxazolone colitis, a new form of experimental colitis. This model is induced
in SJL/J mice by the rectal instillation of the haptenating agent, oxazolone, and is characterized
by a rapidly developing colitis confined to the distal half of the colon; it consists of a mixed ...
Cited by 259 - Related articles - BL Direct - All 6 versions

Oxazolone Colitis: A Murine Model of $# x02009; T Helper Cell Type 2 Colitis …


M Boirivant, IJ Fuss, A Chu, W Strober - The Journal of Experimental …, 1998 - ukpmc.ac.uk
In this study we describe oxazolone colitis, a new form of experimental colitis. This model is induced
in SJL/J mice by the rectal instillation of the haptenating agent, oxazolone, and is characterized
by a rapidly developing colitis confined to the distal half of the colon; it consists of a mixed ...
Related articles

Animal models of inflammatory bowel disease: insights into the …


IJ Fuss, W Strober - Current Opinion in Gastroenterology, 1998 - journals.lww.com
478 Immunology Yet another generalization relating to the murine models of mucosal inflammation
concerns the remarkable fact that although the underlying defects in the various models are exceedingly
diverse, the models resolve them- selves into only two kinds of inflammatory processes. ...
Cited by 8 - Related articles - BL Direct - All 2 versions

Anti–interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental …


IJ Fuss, T Marth, MF Neurath, GR Pearlstein, A Jain, W … - Gastroenterology, 1999 - Elsevier
Given the nature of the T-cell response in TNBS-induced colitis, it is not unexpected that in situ
staining of inflamed intestinal tissue in this disease reveals the presence of an increased number
of IL-12–secreting cells, the cytokine that drives Th1 T-cell differentiation. 10 This finding ...
Cited by 183 - Related articles - BL Direct - All 8 versions

II. The yin and yang of T cells in intestinal inflammation: pathogenic and protective …

- physiology.org
H de Winter, H Cheroutre, M … - American Journal of …, 1999 - Am Physiological Soc
Inflammatory bowel disease (IBD) is a multifactorial immune disorder of uncertain etiology. The
advent of several mouse models of mucosal inflammation that resemble IBD has provided insight
into the mechanisms governing both normal and pathological mucosal immune function. ...
Cited by 52 - Related articles - BL Direct - All 3 versions


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