- ►annals.org T Furuta, K Ohashi, T Kamata, M Takashima, K … - Annals of internal medicine, 1998 - Am Coll Physicians Add to CiteULike Add to Complore Add to Connotea Add to Del.icio.us Add to Digg
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Background: Omeprazole is metabolized by S-mephenytoin 4'-hydroxylase ... Cited by 237 - Related articles - BL Direct - All 4 versions
T Furuta, K Ohashi, K Kosuge, XJ Zhao, M … - Clinical Pharmacology & Therapeutics, 1999 - nature.com Methods: CYP2C19 genotype status for 2 mutations associated with the poor
metabolizer phenotype was determined by a polymerase chain
reaction–restriction fragment length polymorphism method in 16 healthy ... Cited by 160 - Related articles - BL Direct - All 3 versions
T Furuta, N Shirai, M Takashima, F Xiao, H … - Clinical Pharmacology & Therapeutics, 2001 - nature.com 1 First Department of Medicine, the Department of Photodynamic and Endoscopic
Medicine, the First Department of Pathology, and the Department of Clinical
Pharmacology, Hamamatsu University School of Medicine, Hamamatsu, Japan and ... Cited by 130 - Related articles - BL Direct - All 6 versions
T Furuta, N Shirai, M Takashima, F Xiao, H … - Pharmacogenetics and Genomics, 2001 - journals.lww.com Rabeprazole is a potent proton pump inhibitor and is mainly reduced to thioether
rabeprazole by a non-enzymatic pathway and partially metabolized to demethylated
rabeprazole by CYP2C19 in the liver. We intended to determine a cure rate ... Cited by 77 - Related articles - BL Direct - All 5 versions
T Kubota, K Chiba, T Ishizaki - Clinical Pharmacology & Therapeutics, 1996 - nature.com Methods: One hundred eighty-six unrelated, healthy Japanese subjects were
genotyped for S-mephenytoin 4'-hydroxylase (CYP2C19) according to a genotyping
technique to identify the wild-type (wt) gene and two mutations, CYP2C19 m1 ... Cited by 163 - Related articles - BL Direct - All 4 versions
Y Tanigawara, N Aoyama, T Kita, K … - Clinical Pharmacology & Therapeutics, 1999 - nature.com Present address: Department of Hospital Pharmacy, School of Medicine, Keio
University, Shinjuku-ku, Tokyo 160-8582, Japan. ... Present address: Department
of Drug Informatics, Faculty of Pharmaceutical Sciences, Josai University, ... Cited by 74 - Related articles - BL Direct - All 6 versions
[CITATION] CYP2C19 genotype-related efficacy of omeprazole for the treatment of infection caused by
- ►nih.gov [PDF] M Chang, G Tybring, ML Dahl, E Götharson, M … - British journal of clinical pharmacology, 1995 - pubmedcentral.nih.gov 1 Fourteen healthy Swedish Caucasian subjects were given 20 mg of omeprazole
orally each morning for 8 days. The subjects included five poor metabolisers
(PM) of S-mephenytoin, four heterozygous extensive metabolisers (hetEM) and ... Cited by 132 - Related articles - BL Direct - All 4 versions
N Aoyama, Y Tanigawara, T Kita, T Sakai, K … - Journal of gastroenterology, 1999 - sciencelinks.jp Abstract;Omeprazole is widely used for the treatment of Helicobacter pylori
infection. It is metabolized by cytochrome P450 2C19 enzyme (CYP2C19) in the
liver. Because this enzyme exhibits a genetic polymorphism, patients with ... Cited by 47 - Related articles - Cached - BL Direct - All 5 versions
T Furuta, K Ohashi, K Kobayashi, I Iida, H … - Clin Pharmacol Ther, 1999 - regis.sainz.free.fr Ever since the discovery of Helicobacter pylori, close relationships between H
pylori and upper gastrointesti- nal disorders have been made clear.1-3 Cure of H
pylori infection is extremely efficacious in treatment for these ... Cited by 74 - Related articles - View as HTML - BL Direct - All 4 versions
