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Diagnosis of familial Mediterranean fever by a molecular genetics method


S Eisenberg, I Aksentijevich, Z Deng, DL … - Annals of internal …, 1998 - Am Coll Physicians
Background: Familial Mediterranean fever is a recessively inherited disorder characterized by
episodes of fever with abdominal pain, pleurisy, or arthritis. The familial Mediterranean fever
gene, designated MEFV, was recently cloned, and at least three missense mutations ...
Cited by 70 - Related articles - BL Direct - All 6 versions

[PDF] Diagnosis of Familial Mediterranean Fever by a Molecular Genetics Method


F Mediterranean - Ann Intern Med, 1998 - Am Coll Physicians
Familial Mediterranean fever, or recurrent poly- serositis, is a recessively inherited disorder that
affects Sephardic Jews, Turks, Armenians, and Arabs. In these populations, the carrier frequency
has been estimated to be as high as 1 in 5 persons (1, 2). The disorder is characterized ...
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Assessment of pyrin gene mutations in Turks with familial Mediterranean fever(FMF …


X Chen, N Fischel-Ghodsian, A Cercek, M … - Human …, 1998 - interscience.wiley.com
Familial Mediterranean fever (FMF) is an autosomal recessive disease clinically characterized
by recurrent short self-limited attacks of fever accompanied by peritonitis, pleurisy, and arthritis
and can lead to amyloidosis and renal failure in the longer term. It is prevalent mainly in ...
Cited by 33 - Related articles - BL Direct - All 3 versions

Phenotype-genotype correlation in Jewish patients suffering from familial …


M Dewalle, C Domingo, M Rozenbaum, E … - European journal of …, 1998 - ncbi.nlm.nih.gov
Familial Mediterranean Fever is one of the most frequent recessive disease in non-Ashkenazi
Jews. The gene responsible for the disease (MEFV) has very recently been identified. The M694V
('MED') mutation was found in about 80% of the FMF Jewish (Iraqi and North African) ...
Cited by 103 - Related articles - BL Direct

Non-founder mutations in the MEFV gene establish this gene as the cause of …

- oxfordjournals.org
A Bernot, C Da Silva, JL Petit, C Cruaud, C … - Human Molecular …, 1998 - Oxford Univ Press
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurring
attacks of fever and serositis. It affects primarily North African Jews, Armenians, Turks and
Arabs, in which a founder effect has been demonstrated. The marenostrin-pyrin-encoding ...
Cited by 121 - Related articles - BL Direct - All 4 versions

Familial Mediterranean Fever: From the Clinical Syndrome to the Cloning of the …


M Pras - Scandinavian journal of rheumatology, 1998 - informahealthcare.com
Familial Mediterranean fever (FMF) is a genetic dis- order, transmitted as a recessive trait
(1). Unlike most genetic disorders, FMF is not a universal disease. It a¡ects mainly three nations
^ Jews, Armenians, and Turks ^ but also a¡ects Arabs and other minorities of the Middle ...
Cited by 51 - Related articles - BL Direct - All 8 versions

Familial Mediterranean fever: clinical and genetic characterization in a mixed …

- prontodiagnostics.com [PDF] 
R Brik, M Shinawi, I Kepten, M Berant, R Gershoni- … - Pediatrics, 1999 - Am Acad Pediatrics
Results. The M694V mutation, which is predominant in non-Ashkenazi Jews, was found in
92% of our Jewish patients and in only 30% of the Arab patients. All four mutations were identified
among 94% of the Arab patients, but with no particular prevalence for any one of them. ...
Cited by 61 - Related articles - BL Direct - All 6 versions

Familial Mediterranean fever at the millennium: clinical spectrum, ancient …


J Samuels, I Aksentijevich, Y Torosyan, M Centola, Z … - Medicine, 1998 - journals.lww.com
Skip Navigation Links Home > July 1998 - Volume 77 - Issue 4 > Familial Mediterranean Fever
at the Millennium: Clinical Spe... ... Samuels, Jonathan; Aksentijevich, Ivona; Torosyan,
Yelizaveta; Centola, Michael; Deng, Zuoming; Sood, Raman; Kastner, Daniel L.
Cited by 163 - Related articles - BL Direct - All 5 versions

Criteria for the diagnosis of familial Mediterranean fever


A Livneh, P Langevitz, D Zemer, N Zaks, S … - Arthritis Care & … - interscience.wiley.com
Methods. Twenty-seven features and manifestations typical of FMF were studied to determine
their prevalence in 105 patients with FMF and 106 controls. Diagnosis of FMF in the study group
was based on clinical judgment. Controls were patients with a variety of other diseases ...
Cited by 352 - Related articles - BL Direct - All 4 versions

Clinical versus genetic diagnosis of familial Mediterranean fever

- oxfordjournals.org
G Grateau, C Pecheux, C Cazeneuve, D Cattan, M … - QJM, 2000 - Oxford Univ Press
The diagnosis of familial Mediterranean fever (FMF) has until recently been based on clinical
signs alone. Discovery of the MEFV gene has enabled a molecular approach to diagnosis, which
is already well established for diagnosing typical clinical forms of FMF. We evaluated the ...
Cited by 34 - Related articles - BL Direct - All 4 versions


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