- ►annals.org SE Straus, M Sneller, MJ Lenardo, JM Puck, W … - Annals of internal medicine, 1999 - Am Coll Physicians The autoimmune lymphoproliferative syndrome (ALPS) affords novel insights into
the mechanisms that regulate lymphocyte homeostasis and underlie the development
of autoimmunity. This syndrome arises early in childhood in persons who ... Cited by 189 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] CE Jackson, RE Fischer, AP Hsu, SM Anderson … - The American Journal of Human Genetics, 1999 - Elsevier Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte
homeostasis and immunological tolerance. Most patients have a heterozygous
mutation in the APT1 gene, which encodes Fas (CD95, APO-1), mediator of an ... Cited by 115 - Related articles - BL Direct - All 9 versions
J Wang, L Zheng, A Lobito, FKM Chan, J Dale, … - CELL-CAMBRIDGE MA-, 1999 - cell.com Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte
homeostasis and immunological tolerance. Most patients have a heterozygous
mutation in the gene, which encodes Fas (CD95, APO-1), mediator of an ... Cited by 386 - Related articles - Cached - BL Direct - All 13 versions
- ►hematologylibrary.org U Dianzani, M Bragardo, D DiFranco, C … - Blood, 1997 - bloodjournal.hematologylibrary.org Fas (CD95) is a transmembrane molecule that induces programmed cell death (PCD)
of lymphocytes. We examined its function in children with chronic
thrombocytopenia, serum autoantibodies, and lymphadenopathy and/or ... Cited by 118 - Related articles - BL Direct - All 5 versions
- ►hematologylibrary.org F Rieux-Laucat, S Blachere, S Danielan, JP De … - Blood, 1999 - bloodjournal.hematologylibrary.org From the Department of Pediatric Immunology, Unit INSERM U429, Hôpital
Necker-Enfants-Malades, Paris, France; the Department of Pediatric Immunology,
Hospital Garrahan, Buenos-Aires, Argentina; the Department of Clinical ... Cited by 87 - Related articles - BL Direct - All 5 versions
- ►bloodjournal.org MC Sneller, J Wang, JK Dale, W Strober, LA … - Blood, 1997 - Am Soc Hematology Programmed cell death (apoptosis) of activated lymphocytes is critical to immune
homeostasis. The cell surface protein Fas (CD95) and its ligand play a pivotal
role in regulating lymphocyte apoptosis, and defective expression of either ... Cited by 228 - Related articles - BL Direct - All 6 versions
- ►amjpathol.org MS Lim, SE Straus, JK Dale, TA Fleisher, M … - American Journal of Pathology, 1998 - ASIP The defects in lymphocyte apoptosis that underlie the autoimmune
lymphoproliferative syndrome (ALPS) are usually attributable to inherited
mutations of the CD95 (Fas) gene. In this report, we present the ... Cited by 101 - Related articles - BL Direct - All 5 versions
VC Canale, CH Smith - The Journal of pediatrics, 1967 - Elsevier June, 1967 The Journal of PEDIATRICS 891 Chronic lymphadenopathy simulating
malignant lymphoma A new symptom-complex is described characterized by onset of
symptoms between 1 month and 2 years of age: significantgeneralized ... Cited by 120 - Related articles - All 6 versions
JW Ten Bosch, P Schotte, A Ferster, N Azzi, T … - British journal of haematology, 2002 - interscience.wiley.com Summary.Autoimmune lymphoproliferative syndrome (ALPS) is a paediatric disease
characterized by lymphoproliferation and autoimmunity. Most patients are known
to carry heterozygous mutations of the TNFRSF6 gene leading to diminished ... Cited by 42 - Related articles - BL Direct - All 5 versions