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Scholar Results 1 - 10 of about 101 related to Straus: An inherited disorder of lymphocyte apoptosis: the autoimmune lymphoproliferative syndrome. (0.12 sec) 

An inherited disorder of lymphocyte apoptosis: the autoimmune lymphoproliferative …

- annals.org
SE Straus, M Sneller, MJ Lenardo, JM Puck, W … - Annals of internal medicine, 1999 - Am Coll Physicians
The autoimmune lymphoproliferative syndrome (ALPS) affords novel insights into
the mechanisms that regulate lymphocyte homeostasis and underlie the development
of autoimmunity. This syndrome arises early in childhood in persons who ...
Cited by 189 - Related articles - BL Direct - All 5 versions

Autoimmune lymphoproliferative syndrome with defective Fas: genotype influences …

- nih.gov [PDF] 
CE Jackson, RE Fischer, AP Hsu, SM Anderson … - The American Journal of Human Genetics, 1999 - Elsevier
Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte
homeostasis and immunological tolerance. Most patients have a heterozygous
mutation in the APT1 gene, which encodes Fas (CD95, APO-1), mediator of an ...
Cited by 115 - Related articles - BL Direct - All 9 versions

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell …


J Wang, L Zheng, A Lobito, FKM Chan, J Dale, … - CELL-CAMBRIDGE MA-, 1999 - cell.com
Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte
homeostasis and immunological tolerance. Most patients have a heterozygous
mutation in the gene, which encodes Fas (CD95, APO-1), mediator of an ...
Cited by 386 - Related articles - Cached - BL Direct - All 13 versions

Deficiency of the Fas apoptosis pathway without Fas gene mutations in pediatric patients …

- hematologylibrary.org
U Dianzani, M Bragardo, D DiFranco, C … - Blood, 1997 - bloodjournal.hematologylibrary.org
Fas (CD95) is a transmembrane molecule that induces programmed cell death (PCD)
of lymphocytes. We examined its function in children with chronic
thrombocytopenia, serum autoantibodies, and lymphadenopathy and/or ...
Cited by 118 - Related articles - BL Direct - All 5 versions

Lymphoproliferative syndrome with autoimmunity: a possible genetic basis for dominant …

- hematologylibrary.org
F Rieux-Laucat, S Blachere, S Danielan, JP De … - Blood, 1999 - bloodjournal.hematologylibrary.org
From the Department of Pediatric Immunology, Unit INSERM U429, Hôpital
Necker-Enfants-Malades, Paris, France; the Department of Pediatric Immunology,
Hospital Garrahan, Buenos-Aires, Argentina; the Department of Clinical ...
Cited by 87 - Related articles - BL Direct - All 5 versions

Clinical, immunologic, and genetic features of an autoimmune lymphoproliferative …

- bloodjournal.org
MC Sneller, J Wang, JK Dale, W Strober, LA … - Blood, 1997 - Am Soc Hematology
Programmed cell death (apoptosis) of activated lymphocytes is critical to immune
homeostasis. The cell surface protein Fas (CD95) and its ligand play a pivotal
role in regulating lymphocyte apoptosis, and defective expression of either ...
Cited by 228 - Related articles - BL Direct - All 6 versions

Pathological findings in human autoimmune lymphoproliferative syndrome

- amjpathol.org
MS Lim, SE Straus, JK Dale, TA Fleisher, M … - American Journal of Pathology, 1998 - ASIP
The defects in lymphocyte apoptosis that underlie the autoimmune
lymphoproliferative syndrome (ALPS) are usually attributable to inherited
mutations of the CD95 (Fas) gene. In this report, we present the ...
Cited by 101 - Related articles - BL Direct - All 5 versions

Chronic lymphadenopathy simulating malignant lymphoma*


VC Canale, CH Smith - The Journal of pediatrics, 1967 - Elsevier
June, 1967 The Journal of PEDIATRICS 891 Chronic lymphadenopathy simulating
malignant lymphoma A new symptom-complex is described characterized by onset of
symptoms between 1 month and 2 years of age: significantgeneralized ...
Cited by 120 - Related articles - All 6 versions

Reversion of autoimmune lymphoproliferative syndrome with an antimalarial drug: preliminary …


JW Ten Bosch, P Schotte, A Ferster, N Azzi, T … - British journal of haematology, 2002 - interscience.wiley.com
Summary.Autoimmune lymphoproliferative syndrome (ALPS) is a paediatric disease
characterized by lymphoproliferation and autoimmunity. Most patients are known
to carry heterozygous mutations of the TNFRSF6 gene leading to diminished ...
Cited by 42 - Related articles - BL Direct - All 5 versions

Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative …

- nih.gov [PDF] 
J Wu, J Wilson, J He, L Xiang, PH Schur, JD … - Journal of Clinical Investigation, 1996 - pubmedcentral.nih.gov
J. Clin. Invest. © The American Society for Clinical Investigation, Inc.
0021-9738/96/09/1107/07 $2.00 Volume 98, Number 5, September 1996, 1107–1113
... Fas Ligand Mutation in a Patient with Systemic Lupus Erythematosus and ...
Cited by 296 - Related articles - BL Direct - All 10 versions


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