- ►annals.org LM Levy, MC Dalakas, MK Floeter - Annals of internal medicine, 1999 - Am Coll Physicians The cause of the stiff-person syndrome is unknown; however, an autoimmune
pathogenesis is suspected because of 1) the presence of antibodies against
glutamic acid decarboxylase (GAD), the rate-limiting enzyme for the ... Cited by 67 - Related articles - BL Direct - All 6 versions
MC Dalakas, M Fujii, M Li, B McElroy - Neurology, 2000 - AAN Enterprises Address correspondence and reprint requests to Dr. Marinos C. Dalakas,
Neuromuscular Diseases Section, NINDS, National Institutes of Health, Building
10, Room 4N248, 10 Center Drive MSC 1382, Bethesda, MD 20892-1382. Cited by 66 - Related articles - BL Direct - All 3 versions
K Dinkel, HM Meinck, KM Jury, W Karges, W … - Annals of neurology, 1998 - interscience.wiley.com Stiff-man syndrome (SMS) is a rare disorder of the central nervous system
thought to result from an impairment of -aminobutyric acid (GABA)ergic
neurotransmission. Autoantibodies to the GABA-synthesizing enzyme glutamic ... Cited by 91 - Related articles - BL Direct - All 4 versions
MC Dalakas, M Li, M Fujii, DM Jacobowitz - Neurology, 2001 - AAN Enterprises Methods: — The authors studied 18 patients with SPS and positive serum
immunoreactivity to gamma-aminobutyric acid (GABA)-ergic neurons. The reactivity
of serum and CSF to purified GAD antigen was examined by Western blots, and ... Cited by 77 - Related articles - BL Direct - All 3 versions
P Brown, CD Marsden - Journal of neurology, 1999 - Springer Abstract Rigidity in the setting of continuous motor unit activity at rest can
be caused by a variety of central and peripheral conditions. A central origin is
suggested by the presence of painful reflex spasms. Focal spinal lesions ... Cited by 61 - Related articles - BL Direct - All 4 versions
MH Butler, A Hayashi, N Ohkoshi, C Villmann … - Neuron, 2000 - Elsevier Stiff-Man syndrome (SMS) is a rare disease of the central nervous system (CNS)
characterized by chronic rigidity, spasms, and autoimmunity directed against
synaptic antigens, most often the GABA-synthesizing enzyme glutamic acid ... Cited by 67 - Related articles - BL Direct - All 3 versions
HM Meinck, K Ricker, PJ Hülser, M Solimena - Journal of neurology, 1995 - Springer Abstract The neurophysiological findings in eight patients with the stiff man
syndrome (SMS), including four of six tested with autoantibodies against
glutamic acid decarboxylase, are presented. Neurophysiological findings did ... Cited by 47 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org F Sandbrink, NA Syed, MD Fujii, MC Dalakas, … - Brain, 2000 - Oxford Univ Press Muscle stiffness in stiff-person syndrome (SPS) is produced by continuous,
involuntary firing of motor units that is thought to be caused by an autoimmune
mediated dysfunction of GABA-ergic inhibitory neurones. We have postulated ... Cited by 28 - Related articles - BL Direct - All 4 versions
LM Levy, I Levy-Reis, M Fujii, MC Dalakas - Archives of Neurology, 2005 - Am Med Assoc Background Patients with stiff-person syndrome (SPS) have circulating antibodies
against glutamic acid decarboxylase, the rate-limiting enzyme responsible for
the synthesis of -aminobutyric acid (GABA). Although the patients' symptoms ... Cited by 23 - Related articles - All 4 versions
