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Scholar Results 1 - 10 of about 101 related to Vadhan-Raj: Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopen.... (0.11 sec) 

Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia …

- annals.org [PDF] 
S Vadhan-Raj, CF Verschraegen, C Bueso- … - Annals of internal medicine, 2000 - Am Coll Physicians
Saroj Vadhan-Raj, MD; Claire F. Verschraegen, MD; Carlos Bueso-Ramos, MD; Hal E.
Broxmeyer, PhD; Andrzej P. Kudelka, MD; Ralph S. Freedman, MD, PhD; Creighton L.
Edwards, MD; David Gershenson, MD; Dennie Jones, MD; Mark Ashby, PhD; and ...
Cited by 92 - Related articles - BL Direct - All 4 versions

[PDF] Table. Effect of Recombinant Human Thrombopoietin Treatment on Carboplatin-Induced …


P Count - Ann Intern Med, 2000 - hem-aids.ru
Saroj Vadhan-Raj, MD; Claire F. Verschraegen, MD; Carlos Bueso-Ramos, MD; Hal E.
Broxmeyer, PhD; Andrzej P. Kudelka, MD; Ralph S. Freedman, MD, PhD; Creighton L.
Edwards, MD; David Gershenson, MD; Dennie Jones, MD; Mark Ashby, PhD; and ...
Related articles - View as HTML

Enhancement of platelet recovery after myelosuppressive chemotherapy by recombinant …

- jcojournal.org
RL Basser, C Underhill, I Davis, MD Green, J … - Journal of Clinical Oncology, 2000 - jcojournal.org
PATIENTS AND METHODS: In this open-label study, 68 patients with advanced cancer
were randomized to receive PEG-rHuMGDF subcutaneously at different doses and
durations before administration of carboplatin 600 mg/m 2 , ...
Cited by 30 - Related articles - BL Direct - All 7 versions

A double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte …

- hematologylibrary.org
CA Schiffer, K Miller, RA Larson, PC Amrein, … - Blood, 2000 - bloodjournal.hematologylibrary.org
Lineage-specific preparations of thrombopoietin have been known to produce
marked increases in the megakaryocyte mass and the platelet count after
subcutaneous dosing. 1 , 2 After promising results in preclinical murine 3 ...
Cited by 59 - Related articles - BL Direct - All 3 versions

A randomized, double-blind, placebo-controlled study with pegylated recombinant human …

- bloodjournal.org
E Archimbaud, OG Ottmann, JAL Yin, K … - Blood, 1999 - Am Soc Hematology
To determine the safety, biologic, and clinical benefits of pegylated
recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF;
Amgen, Thousand Oaks, CA) after myelosuppressive chemotherapy in acute ...
Cited by 67 - Related articles - BL Direct - All 5 versions

Stimulation of megakaryocyte and platelet production by a single dose of recombinant human …

- annals.org
S Vadhan-Raj, LJ Murray, C Bueso-Ramos, S … - Annals of internal medicine, 1997 - Am Coll Physicians
Background: Thrombocytopenia is frequently encountered in patients with cancer.
It is associated with an increased risk for clinically important bleeding
episodes, which increases the demand for platelet transfusion.
Cited by 157 - Related articles - BL Direct - All 6 versions

Thrombopoietin therapy increases platelet yields in healthy platelet donors

- bloodjournal.org
DJ Kuter, LT Goodnough, J Romo, J DiPersio, … - Blood, 2001 - Am Soc Hematology
Platelet transfusions are essential to prevent morbidity and mortality in
patients who are severely thrombocytopenic. Platelets for transfusion are
currently obtained either by fractionation of whole blood or by platelet ...
Cited by 43 - Related articles - BL Direct - All 4 versions

Thrombocytopenia caused by the development of antibodies to thrombopoietin

- bloodjournal.org
J Li, C Yang, Y Xia, A Bertino, J Glaspy, M … - Blood, 2001 - Am Soc Hematology
In these clinical studies, both recombinant TPOs were safe and not associated
with thrombosis. However, PEG-rHuMGDF was paradoxically associated with the
development of persistent thrombocytopenia (platelet count 100 × 10 9 /L) ...
Cited by 222 - Related articles - BL Direct - All 4 versions

A phase I trial of recombinant human thrombopoietin in patients with delayed platelet …

- cjp.com [PDF] 
RA Nash, R Kurzrock, J DiPersio, J Vose, C … - Biology of Blood and Marrow Transplantation, 2000 - Elsevier
Delayed platelet recovery is a significant complication after both autologous
and allogeneic hematopoietic stem cell transplantation (HSCT). A multicenter,
phase I dose-escalation study of recombinant human thrombopoietin (rhTPO) ...
Cited by 38 - Related articles - BL Direct - All 7 versions

Phase 1 study of pegylated recombinant human megakaryocyte growth and development factor …


B Bolwell, J Vredenburgh, B Overmoyer, C … - Bone marrow transplantation, 2000 - ncbi.nlm.nih.gov
Forty-seven patients with stage II, III, or IV breast cancer undergoing
autologous peripheral blood progenitor cell (PBPC) transplantation were
randomized to placebo (n = 13) or to one of five sequential dose cohorts of ...
Cited by 24 - Related articles - BL Direct - All 2 versions


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