- ►annals.org [PDF] SM Albelda, R Wiewrodt, JB Zuckerman - Annals of internal medicine, 2000 - Am Coll Physicians Gene therapy, the treatment of any disorder or pathophys- iologic state on the
basis of the transfer of genetic infor- mation, was a high-priority goal in the
1990s. The lung is a major target of gene therapy for genetic disorders, ... Cited by 71 - Related articles - BL Direct - All 7 versions
JB Zuckerman, CB Robinson, KS M, R Shell, … - Human gene therapy, 1999 - liebertonline.com Page 1. HUMAN GENE THERAPY 10:2973–2985 (December 10, 1999) Mary Ann Liebert,
Inc. A Phase I Study of Adenovirus-Mediated Transfer of the ... Cited by 72 - Related articles - BL Direct - All 5 versions
- ►nih.gov RC Boucher - Journal of Clinical Investigation, 1999 - Am Soc Clin Investig Gene therapy for the treatment of cystic fibrosis should be a “natural”:
Cystic fibrosis (CF) is a recessive disease associated with loss of function
mutations in the CF transmembrane conductance regulator (CFTR) gene, which ... Cited by 92 - Related articles - BL Direct - All 13 versions
- Free from Publisher DC Look, SL Brody - American journal of respiratory cell and molecular …, 1999 - ncbi.nlm.nih.gov 1: Am J Respir Cell Mol Biol. 1999 Jun;20(6):1103-6. Engineering viral vectors
to subvert the airway defense response. Look DC, Brody SL. ... Cited by 26 - Related articles - BL Direct - All 4 versions
KS Frederiksen, A Petri, N Abrahamsen, HS … - Lung Cancer, 1999 - Elsevier In the pre-clinical research into the development of gene therapy for cancer,
different strategies have evolved and shown promising results in the laboratory.
However, most of these strategies will need further refinement to obtain ... Cited by 11 - Related articles - All 5 versions
JG Hay, NG McElvaney, J Herena, RG Crystal - Human Gene Therapy, 1995 - liebertonline.com Page 1. HUMAN GEN E THERAP Y 6:1487-1496 (November 1995) Mary Aim Liebert, Inc.
Modificatio nof N asal Epithelial Potential Differences of ... Cited by 80 - Related articles - BL Direct - All 2 versions
A Gautam, CL Densmore, B Xu, JC Waldrep - Molecular Therapy, 2000 - Elsevier Aerosol gene delivery to the pulmonary system has vast potential for many
diseases, including cystic fibrosis and lung cancer. We recently reported that
polyethyleneimine (PEI), a cationic polymer, holds promise as a gene ... Cited by 76 - Related articles - All 5 versions
M Stern, F Sorgi, C Hughes, NJ Caplen, JE … - Gene therapy, 1998 - ncbi.nlm.nih.gov Nebulisation is currently the most acceptable and practical delivery system for
repeated applications of gene therapy to the lower airways of cystic fibrosis
(CF) patients. We have assessed whether this route of administration offers ... Cited by 16 - Related articles - BL Direct - All 2 versions
Q Chu, JA St. George, M Lukason, SH Cheng … - Human gene therapy, 2001 - liebertonline.com Administration of recombinant adenoviral (AdV) vectors to animals can lead to
inflammatory and immune responses. For therapeutic indications in which repeated
treatment is necessary, such as cystic fibrosis (CF), these responses can ... Cited by 39 - Related articles - BL Direct - All 4 versions
YH Chow, J Plumb, Y Wen, BM Steer, Z Lu, M … - Molecular Therapy, 2000 - Elsevier Targeting therapeutic gene expression to disease-affected tissues is an
essential component of effective and safe gene therapy. After birth, CFTR gene
expression in human lungs is localized predominantly in the epithelial ... Cited by 19 - Related articles - All 5 versions
