- ►annals.org [PDF] BF Gage, SD Fihn, RH White - Annals of internal medicine, 2001 - Am Coll Physicians In North America, atrial fibrillation is associated with at least 75 000
ischemic strokes each year. Most of these strokes occur in patients older than
75 years of age. The high incidence of stroke in very elderly persons ... Cited by 51 - Related articles - BL Direct - All 5 versions
RJ Beyth - Clinics in geriatric medicine, 2001 - Elsevier The elderly are the most rapidly growing segment of our society. They also
represent those most likely to have indications that require treatment with
anticoagulant therapy. The prevalence of many thromboembolic disorders, ... Cited by 20 - Related articles - BL Direct - All 3 versions
BF Gage, SD Fihn, RH White - The American journal of medicine, 2000 - Elsevier When initiating warfarin therapy, clinicians should avoid loading doses that can
raise the International Normalized Ratio (INR) excessively; instead, warfarin
should be initiated with a 5-mg dose (or 2 to 4 mg in the very elderly). ... Cited by 83 - Related articles - BL Direct - All 8 versions
G Palareti, J Hirsh, C Legnani, C Manotti, A … - Archives of Internal Medicine, 2000 - Am Med Assoc Results Bleeding rate was 9.9% and 6.6% patient-years in elderly and young
patients, respectively (P = .07), and 2.1% and 1.1% for major bleeding (P =
.19); 6 and 1 events, respectively, were fatal (all intracranial, relative ... Cited by 89 - Related articles - BL Direct - All 4 versions
W Ageno, A Squizzato, F Dentali, M Crowther - The American journal of medicine, 2005 - Elsevier This need to minimize the time required to achieve a therapeutic INR in the
outpatient setting, without causing overanticoagulation, has led to the testing
of various algorithms for the initiation of warfarin. Unfortunately, most ... Cited by 6 - Related articles - All 7 versions
MD Ezekowitz, KE James, MJ Radford, FR … - Journal of Cardiovascular Pharmacology and …, 1999 - cpt.sagepub.com Michael D. Ezekowitz, MD, PhD,* Kenneth E. James, PhD, † ... Martha J.
Radford, MD, ‡ Frederick R. Rickles, MD ‡ Nadia Redmond, MSPH
§ ... From the *Cardiology Section, VA Medical Center, West Haven, Cited by 13 - Related articles - BL Direct - All 2 versions
- ►temple.edu [PDF] BF Gage, E Birman-Deych, R Kerzner, MJ … - The American journal of medicine, 2005 - Elsevier Rates (95% confidence interval [CI]) of intracranial hemorrhage per 100
patient-years were 2.8 (1.9–4.1) in patients at high risk for falls and 1.1
(1.0–1.3) in other patients. Rates (95% CI) of traumatic intracranial ... Cited by 61 - Related articles - All 14 versions
V Siguret, I Gouin, M Debray, C Perret- … - The American journal of medicine, 2005 - Elsevier The predicted daily maintenance warfarin dose (3.1 ± 1.6 mg/d) correlated
closely with the actual maintenance dose (3.2 ± 1.7 mg/d; R 2 = 0.84). The
predicted dose was equal to the actual dose in 77 patients (73%; 95% ... Cited by 48 - Related articles - All 6 versions
MB O'Connell, PR Kowal, CJ Allivato, TL … - Pharmacotherapy, 2000 - PPI Although warfarin is effective and safe in the elderly, reluctance to treat
these patients with the drug exists. This results from warfarin being difficult
to dose coupled with concerns about bleeding and challenges with ... Cited by 17 - Related articles - BL Direct - All 3 versions
