- ►annals.org [PDF] S Middeldorp, JR Meinardi, MMW Koopman, E … - Annals of internal medicine, 2001 - Am Coll Physicians Background: The factor V Leiden mutation is a common genetic defect associated
with an increased risk for venous thromboem- bolism. The clinical implications
for asymptomatic carriers of this mutation and, consequently, the ... Cited by 120 - Related articles - All 11 versions
- ►hematologylibrary.org P Simioni, D Tormene, P Prandoni, P Zerbinati … - Blood, 2002 - bloodjournal.hematologylibrary.org Factor V Leiden mutation (factor V Arg506 Gln) is the most common genetic defect
associated with an increased risk for venous thromboembolism (VTE). 1-3 Its
prevalence in the white population is approximately 5% and is as high as ... Cited by 71 - Related articles - BL Direct - All 6 versions
- ►annals.org S Middeldorp, C Henkens, MMW Koopman, E … - Annals of internal medicine, 1998 - Am Coll Physicians Background: The factor V Leiden mutation is a genetic defect associated with an
increased incidence of venous thromboembolism. When the incidence of venous
thromboembolism in relatives of patients known to have the mutation ... Cited by 150 - Related articles - BL Direct - All 8 versions
WW Grody, JH Griffin, AK Taylor, BR Korf, JA … - Genetics in Medicine, 2001 - journals.lww.com Recommendation 1 When appropriate clinical care requires testing for the factor
V Leiden allele, either direct DNA-based genotyping or a factor V
Leiden-specific functional assay is recommended. Patients who test positive ... Cited by 124 - Related articles - BL Direct - All 4 versions
P Simioni, BJ Sanson, P Prandoni, D Tormene, … - Thrombosis and haemostasis, 1999 - cat.inist.fr The risk of spontaneous or risk-period related venous thromboembolism in family
members of symptomatic carriers of antithrombin(AT), protein C(PC) or protein
S(PS) defects, as well as of the Factor V Leiden mutation is still ... Cited by 224 - Related articles - BL Direct - All 4 versions
FR Rosendaal - openaccess.leidenuniv.nl The factor VLeiden mutation (FVL) leads to a seven-fold increased risk of venous
thromboembolism (VTE). In thrombophilic families, 25% of carriers have
experienced thrombosis before the age of 40 years. Aim of our study was to ... Related articles - View as HTML - All 2 versions
I Martinelli, P Bucciarelli, M Margaglione, V … - British journal of haematology, 2000 - ingentaconnect.com Page 1. British Journal of Haematology, 2000, 111, 1223±1229 The risk of
venous thromboembolism in family members with mutations ... Cited by 92 - Related articles - BL Direct - All 5 versions
RPM Lensen, RM Bertina, H De Ronde, JP … - Thrombosis and haemostasis, 2000 - cat.inist.fr The factor V Leiden mutation(FVL) leads to a seven-fold increased risk of venous
thromboembolism(VTE). In thrombophilic families, 25% of carriers have
experienced thrombosis before the age of 40 years. Aim of our study was to ... Cited by 56 - Related articles - BL Direct - All 3 versions
- ►annals.org [PDF] K Juul, A Tybjaerg-Hansen, P Schnohr, BG … - Annals of internal medicine, 2004 - Am Coll Physicians Factor V Leiden and the Risk for Venous Thromboembolism in the ... Klaus Juul,
MD; Anne Tybjærg-Hansen, MD, DMSc; Peter Schnohr, MD; and Børge G.
Nordestgaard, MD, DMSc ... Background: Odds ratios for venous ... Cited by 65 - Related articles - All 8 versions
T Baglin, R Luddington, K Brown, C Baglin - The Lancet, 2003 - Elsevier At 2 years, the cumulative recurrence rate in 570 patients was 11%. Incidence
was lowest after surgery-related VTE (0%) and highest after unprecipitated VTE
(19·4%) (p<0·001). 85% of patients were tested for heritable ... Cited by 207 - Related articles - All 8 versions
