- ►annals.org [PDF] KA Bauer - Annals of internal medicine, 2001 - Am Coll Physicians Discovery of the factor V Leiden and prothrombin G20210A mu- tations has greatly
increased the percentage of patients in whom venous thrombosis can be attributed
to hereditary thrombophilia. The first step in the diagnostic approach to ... Cited by 153 - Related articles - All 8 versions
[CITATION] The hypercoagulable state: evaluation and management
- ►hematologylibrary.org PM Mannucci - Blood, 2001 - bloodjournal.hematologylibrary.org Dahlback in 1993 and Bertina in 1994 made the landmark discovery that resistance
to activated protein C due to a point mutation in the factor V gene (G1691A in
exon 10, leading to Arg506Gln) is associated with a 6- to 8-fold increased ... Cited by 39 - Related articles - BL Direct - All 6 versions
S Eichinger, I Pabinger, A Stümpflen, M … - Thrombosis and haemostasis, 1997 - cat.inist.fr Thromboprophylaxis with oral anticoagulants up to six months is established in
patients after a first venous thromboembolic event(VTE). The risk of recurrent
VTE is still considerable thereafter, and it is uncertain whether some ... Cited by 170 - Related articles - BL Direct - All 3 versions
M Makris, FR Rosendaal, FE Preston - JOURNAL OF INTERNAL MEDICINE-OXFORD- …, 1997 - openaccess.leidenuniv.nl Abstract. There are now a number of potential candi- dates for inherited
thrombophilia but a definite causal relationship has been established for only a
proportion of these. Accepted causes of familial thrombophilia include the ... Cited by 51 - Related articles - View as HTML - BL Direct - All 4 versions
M Margaglione, G D'ANDREA, D Colaizzo, G … - Thrombosis and haemostasis, 1999 - cat.inist.fr Patients carrying the FV Leiden or the FII A 20210 mutation have a high
risk of venous thromboembolism. Among 542 patients with a documented diagnosis
of deep venous thrombosis in one leg consecutively referred for a ... Cited by 103 - Related articles - BL Direct - All 5 versions
JR Meinardi, S Middeldorp, PJ de Kam, MMW … - British journal of haematology, 2002 - dissertations.ub.rug.nl Johan R. Meinardi, Saskia Middeldorp, Pieter J. de Kam, Maria MW Koopman,
Elisabeth CM van Pampus, Karly Hamulyák, Martin H. Prins, Harry R. Büller, and
Jan van der Meer ... Background: The duration of anticoagulant treatment ... Cited by 43 - Related articles - View as HTML - BL Direct - All 9 versions
V De Stefano, I Martinelli, PM Mannucci, K … - The New England journal of medicine, 1999 - nejm.highwire.org Results Patients who were heterozygous for factor V Leiden alone had a risk of
recurrent deep venous thrombosis that was similar to that among patients who had
neither mutation (relative risk, 1.1; 95 percent confidence interval, 0.7 ... Cited by 393 - Related articles - BL Direct - All 7 versions
- ►bmj.com FP Sarasin, H Bounameaux - British Medical Journal, 1998 - bmj.com Before screening for any abnormality is advocated in more or less selected
groups of symptomatic or asymptomatic patients, however, data should demonstrate
that carriers of the mutation would benefit from the diagnosis. For ... Cited by 41 - Related articles - BL Direct - All 6 versions
C Kearon, M Crowther, J Hirsh - Annual review of medicine, 2000 - Annual Reviews ▪ Abstract The inherited hypercoagulable states can be divided into those that
are common and associated with a modest risk of thrombosis (ie factor V Leiden
and G20210A prothrombin gene) and those that are uncommon but asssociated ... Cited by 98 - Related articles - BL Direct - All 4 versions
