J Raedle, J Trojan, A Brieger, N Weber, D … - Annals of internal medicine, 2001 - Am Coll Physicians Background: Microsatellite instability is a hallmark of mismatch repair
deficiency in hereditary nonpolyposis colorectal cancer and results from
mutations in the mismatch repair genes MLH1 or MSH2 or from gene ... Cited by 59 - Related articles - BL Direct - All 5 versions
JP Terdiman, TR Levin, BA Allen, JR Gum, A … - Gastroenterology, 2002 - Elsevier Forty-three probands were enrolled from UCSF and 23 from KP. The UCSF and KP
probands had similar median age of onset of CRC (30 vs. 31 years) and the
percentage with any personal or family history of another HNPCGrelated ... Cited by 20 - Related articles - BL Direct - All 9 versions
- ►nih.gov G Plotz, J Raedle, A Brieger, J Trojan, S … - Nucleic acids research, 2002 - Oxford Univ Press The DNA binding properties of hMutS and hMutL and complex formation of hMutS
with hMutL and hMutLß were investigated using binding experiments on magnetic
bead-coupled DNA substrates with nuclear extracts as well as purified ... Cited by 18 - Related articles - BL Direct - All 5 versions
- ►aacrjournals.org SS Wahlberg, J Schmeits, G Thomas, M Loda, … - Cancer research, 2002 - AACR Forty-eight hereditary nonpolyposis colorectal carcinoma (HNPCC) familiesfor
which a tumor sample was available were evaluated for the presence of germ-line
mutations in MSH2 and MLH1, tumor microsatellite instability (MSI), and ... Cited by 133 - Related articles - BL Direct - All 4 versions
HP Wüllenweber, C Sutter, F Autschbach, F … - Diseases of the Colon & Rectum, 2001 - Springer PURPOSE: The Bethesda guidelines were developed for selection of patients whose
tumors should be tested for high microsatellite instability. This study examined
the va- lidity of the different Bethesda criteria in relation to micro- ... Cited by 24 - Related articles - BL Direct - All 4 versions
JP Terdiman, JR Gum, PG Conrad, GA Miller, … - Gastroenterology, 2001 - Elsevier The optimal strategy for the detection of hereditary nonpolyposis colorectal
cancer (HNPCC) gene carriers remains uncertain. We evaluated whether
microsatellite instability (MSI) analysis or MSH2 and MLH1 protein ... Cited by 124 - Related articles - BL Direct - All 12 versions
P Hutter, A Couturier, V Membrez, F Joris, … - International Journal of Cancer, 1998 - interscience.wiley.com Lynch syndrome, or hereditary non-polyposis colorectal cancer (HNPCC), is a
consequence of a dominantly inherited susceptibility to accumulate somatic
mutations. The disorder is manifested as a familial aggregation of ... Cited by 33 - Related articles - BL Direct - All 4 versions
W Kievit, J de Bruin, EMM Adang, MJL … - Clinical genetics, 2004 - interscience.wiley.com Present guidelines to identify hereditary non-polyposis colorectal cancer
(HNPCC) families are criticized for limitations in accuracy. The Amsterdam
criteria I and II (AC I and AC II) are used to predict a germline mutation ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►bmj.com [PDF] JG Stone, D Robertson, RS Houlston - British Medical Journal, 2001 - jcp.bmj.com Page 1. doi:10.1136/jcp.54.6.484 2001;54;484-487 J. Clin. Pathol. JG Stone,
D Robertson and RS Houlston colorectal cancer method ... Cited by 47 - Related articles - BL Direct - All 8 versions
D Sources, T Horizon - Ann Intern Med, 2001 - Am Coll Physicians Cost-Effectiveness of Microsatellite Instability Screening as a Method ...
Scott D. Ramsey, MD, PhD; Lauren Clarke, MS; Ruth Etzioni, PhD; Mitchell
Higashi, MBA; Kristin Berry, MS; and Nicole Urban, ScD Cited by 78 - Related articles - BL Direct - All 8 versions
